Neurophysiology Flashcards

1
Q

Where does the initial innervation of the tooth originate?

A

Sensory Trigeminal Ganglia

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2
Q

Development of dental innervation is tightly related to ____ and ____

A

The advancing tooth morphogenesis

Dental cell differentiation

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3
Q

During which stages of tooth development do the nerve fibers establish a nerve plexus beneath the apical foramina

A

Cap and Bell

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4
Q

Nerve fibers innervate the ____, the ____, and ____

A

Subodontoblastic layer
Coronal odontoblast layer
Predentin layer

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5
Q

What is the most common form of pain in the orofacial region

A

Odontologia

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6
Q

Which nerves evoke pain sensations?

A

Interdental nerves

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7
Q

What percentage of US adults do not seek routine dental care for fear of pain?

A

50%

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8
Q

Pulpal nerve fibers contain ____

A

Neuropeptides

  • Calcitonin Gene-Related Peptide (CGRP)
  • Substance P (SP)
  • Neuropeptide Y
  • Neurokinin A
  • Vasoactive Intestinal polypeptide (VIP)
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9
Q

What causes neuropeptide release?

A

Tissue injury
Complement activation
Antigen-antibody reactions
Stimulation of the inferior alveolar nerve

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10
Q

Vasoactive peptides, Mechanical stimulation, and electrical stimulation produce vaso____

A

Vasodilation

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11
Q

Substance P and CGRP ____ and ____ and ____

A

Cause vasodilation
Contribute to hyperalgesia
Promote wound healing

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12
Q

How does the pulp react when insult causes activation of intradental nociceptors

A

Neurogenic vasodilation

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13
Q

Which nerve fibers function in motor and proprioception?

A

A-alpha

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14
Q

Which nerve fibers function in pressure and touch?

A

A-beta

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15
Q

Which nerve fibers function in motor to muscle spindles?

A

A-gamma

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16
Q

Which nerve fibers function in pain, temperature, touch?

A

A-delta

17
Q

Which nerve fibers function in preganglionic autonomics?

A

B

18
Q

Which nerve fibers function in pain only

A

C dorsal root

19
Q

Which types of nerves innervate the pulp?

A

A-delta

C

20
Q

A-delta fibers of the pulp are responsible for:

A

Having their nerve endings at the pulp-dentin border
Dentinal pain/sensitivity
Sharp, well localized pain

21
Q

C fibers of the pulp are responsible for:

A

Heat sensitivity
Dull, poorly localized pain
Pain associated with tissue damage

22
Q

What can alter the function of A-delta fibers?

A

Changes in microcirculation

- Decreased blood flow due to activation of sympathetic vasoconstrictor fibers depresses the dentinal responsiveness