Neuropharmacology

Question 1

What are 4 common features of most neurons?

Answer 1

They all have:
Dendrites
Cell body (Soma)
Axon
Axon Projections

Question 2

Function of dendrites

Answer 2

Communication

These “antennas” of the neuron receives inputs (afferent signals) from adjacent cells

Question 3

Soma (cell body) functions

Answer 3

1. The basic machinery of life
   -contains all organelles found in animal cells
   (nucleus, rough/smooth ER, golgi apparatus, lots of mitochondria)
2. The metabolic center- the site of protein synthesis & packaging

Question 4

Do all neurons have dendrites?

Answer 4

No

Question 5

Does branching of dendrites vary?

Answer 5

Yes. While the average neuron receives 10,000 synaptic inputs to its dendritic tree, the purkinje cells receive about 150,000

Question 6

On avergage, how many synaptic inputs does the dendritic tree receive?

Answer 6

10,000 synaptic inputs

Question 7

Do all cells have membrane potentials?

Answer 7

Yes

Question 8

What are leak channels most permeable to in a resting cell membrane?

Answer 8

K+, because

Question 9

what are inputs?

Answer 9

neurotransmitters interacting with receptors

Question 10

The electrical signals that are generated in response to neurotransmitters in the dendrites are usually referred to as what?

Answer 10

Graded

Question 11

What is the resting membrane potential of a neuron?

Answer 11

-60 to -80mV

Question 12

what limits the leakage of K+ through K+ leak channels?

Answer 12

Ion concentration gradient

Question 13

What is responsible for re-establishing the concentration gradient after an action potential?

Answer 13

Na+/K+ ATPase pump

Question 14

What alllows for rapid changing of membrane potential in a neuron?

Answer 14

Voltage-gated and ligand-gated channels