Neuropathies + Developmental/birth injuries Flashcards
Peripheral neuropathy causes
o diabetes (most common) o Lyme disease o HIV o Shingles o Guillain-Barre
What is a peripheral neuropathy
injury to peripheral N due to injury or illness
Are diabetic neuropathies focal, diffuse, or both
Can be either
What nervous systems do diabetic neuropathies effect
Somatic or autonomic PNS
Diabetic neuropathy Presentation
symmetrical distal pattern (diabetic polyneuropathy)
Diabetic neuropathy Causes
- hyperglycemia leading to abnormal microcirculation
- change in insulin levels alter gene-regulation
- loss of myelinated + non-myelinated fibers
- vascular changes
- nerve growth reduced
Diabetic Neuropathy S&S
- burning pain
- symmetrical sensory changes (paresthesia, burning)
- can be slow or rapid onset (people may not notice it)
- paresthesia: impaired proprioception, touch, pressure
- minimal motor weakness
Diabetic neuropathy Rx
- control hyperglycemia
- symptoms management
- skin care checks* (risk of wound and amputation)
- exercises:
• strength (ankle, hips: strategies for prevention of falling)
• balance
• prevention of damage to skin, joint, muscle, CT
What is complex regional pain syndrome (CRPS)
chronic pain condition
What may cause CRPS
Dysfunction in central or peripheral NS
CRPS presentation
o change in color/temp of the skin over the affected limb or body part
o intense burning pain
o skin sensitivity
o sweating
o swelling
o stiffness
o usually occurs after trauma or immobilization (cast)
CRPS Stages + corresponding presentation
Stage 1 (0-3 months) puffy swelling, redness, warmth, stiffness, allodynia, pos bone scan
Stage 2 (3-6 months) Increased P and stiffness, firm edema, cyanosis, atrophy, osteopenia on xray
Stage 3 (6 months +) tight, smooth, glossy, cool, pale skin - stiffness and contractures, nail and hair changes, severe osteopenia
CRPS Rx
Prevention and early detection
- early ROM, P/edema management (desensitization, contrast baths, modalities), education
What is cerebral palsy (CP)?
Non-progressive lesion of brain, occurs before 2yrs
CP Comorbities
o hearing and speech problems o hydrocephalus o microcephaly o scoliosis o hip dislocation o mental retardation
CP Risk Factors
o prenatal (maternal infection, malnutrition, maternal seizures)
o perinatal (prematurity 27-30 weeks gestation, obstetric complications (breech)
o small for gestational age
o rupture of membranes
o intrauterine infection
o low APGAR
o multiple births
o post-natal: infection, environmental toxins, brain tumor, anoxia, CVA
o loss of autonomic regulation of CNS blood flow until full term
• (cycle of perfusion and reperfusion)