Neurons Flashcards

0
Q

Metabotropic receptors

A

Ligand binds to the receptor and activates intracellular events.
Insulin receptor-activates tyrosine kinase
Janus kinase-the receptor is different from the
GPCRs

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1
Q

Ionotropic receptor

A

Ligand gated ion channels that changes shape when a ligand binds.

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2
Q

Corticospinal neurons

A

Neurons that run the brain to the spinal chord. Cross over in the brain stem.

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3
Q

Increased diameter

A

Increased conductance.

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4
Q

Nernst equation

A

RT/ZF*ln(out/in)

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5
Q

Increased Nernst potential

A

Increased resting potential

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6
Q

Sodium potassium pump

A

Uses ATP to pump potassium in and sodium out. Creates the Na/K gradient which acts as a voltage source.

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7
Q

Voltage

A

(GnaEna+GkEk)/(Gna+Gk)

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8
Q

Curare

A

Antagonist to nicotine binding.

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9
Q

Excitatory

A

More likely to induce action potential

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10
Q

Inhibitory

A

Makes it less to have an action potential

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11
Q

Excitatory postsynaptic potential

A

Voltage increase in postsynaptic neuron.
Ech>T
A single EPSP will not always cause t to cross threshold instead they will have to sum

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12
Q

Synaptic Delay

A

The delay between the action potential in the presynaptic neuron and the EPSP in the postsynaptic neuron.
About 1ns

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13
Q

Inhibitory Postsynaptic Potential

A

Released neurotransmitter makes it harder for the postsynaptic neuron the fire.

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14
Q

Voltage gated Ca Channel

A

Tetramere
Sensitive to voltage and therefore opens with an AP.
Located in the presynaptic neuron and causes Ca to come in which causes the release of neurotransmitter from vesicles.

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15
Q

Firing Rate

A
The action potential frequency. The unit is Hz. 
#impulses/second
16
Q

Excitatory Neuron

A

A presynaptic neuron that affects the postsynaptic neuron in an excitatory way.
Increase A=increase B
Decrease A=decrease B

17
Q

Inhibitory neuron

A

A presynaptic neuron that has inhibitory effects on the postsynaptic neuron.
Increase A = Decrease B
Decrease A = Increase B

18
Q

Skin mechanoreceptor

A

A neuron located on the surface of your skin that is sensitive to touch. It is activates by applied pressure.
Afferent
Tactile neuron

19
Q

IA muscle spindle stretch receptor

A

Neuron embedded within the muscle that detects when a muscle changes length. The length change causes a change in firing rate.

20
Q

Carotid artery baroreceptor

A

This measures the pressure in the carotid artery (aka blood pressure). This acts as the sensor in a negative feedback loop that ensures adequate blood to the brain.

21
Q

Knee extensor muscle

A

The muscle connected to the top of the patellar tendon. This is the muscle that causes the knee reflex because of the activation of the spindle stretch receptors within the muscle.