Neurones and Synaptic Transmission Flashcards

1
Q

How many neurones are in the human nervous system? How many of those are located in the brain?

A

100 billion

80%

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2
Q

What is the purpose of a neurone? What does this provide the nervous system?

A

Transmit signals electrically and chemically which provides nervous system its primary means of communication

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3
Q

Name the three types of neurones

A

Sensory
Relay
Motor

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4
Q

Describe the function of a sensory neurone and its structure

A

Carry messages from PNS to CNS

Long dendrites and short axons

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5
Q

Describe the function of a relay neurone and its structure

A

Connect sensory neurons to motor or other relay neurones

Short dendrites and short axons

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6
Q

Describe the function of a motor neurone and its structure

A

Connect CNS to effectors

Short dendrites and long axons

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7
Q

How does the size of neurones vary?

A

Less than a mm to a metre

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8
Q

Name the seven basic structures of a neurone

A
Cell body
Nucleus
Dendrites
Axon
Myelin sheath
Nodes of Ranvier
Terminal buttons
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9
Q

Describe the structure of dendrites and their function

A

Branch like structures that protrude from the cell body Carry nerve impulses from neighbouring neurones towards cell body

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10
Q

Describe the function of an axon

A

Carries impulses away from cell body down neurone

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11
Q

What is the myelin sheath and two of their functions?

A

Fatty layer that covers the axon

Protection and speeds up electrical transmission of impulse

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12
Q

What are the nodes of Ranvier and their function?

A

Gaps in the myelin sheath

To speed up transmission by forcing it to ‘jump’ across gaps along the axon

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13
Q

Where are terminal buttons on a neurone and what is their function?

A

End of an axon

Communicate with next neurone in chain across a gap (synapse)

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14
Q

Describe the process of firing a neuron (3)

A

When a neuron is in a resting state the inside of the nerve cell is negatively charged compared to the outside
When neuron activated by a stimulus, inside of cell becomes positively charged for a split second causing an action potential to occur
Creates an electrical impulse than travels down the axon towards end of neuron

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15
Q

Define neurotransmitter

A
Brain chemicals 
released from synaptic vesicles 
relay signals 
across synapse 
from one neuron to another
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16
Q

Define synaptic transmission

A

Process by which neighbouring neurons communicate with each other by sending chemical messages across the synapse

17
Q

Describe the process of electrical transmission (6)

A

Electrical impulse reaches presynaptic terminal
Triggers release of neurotransmitters from the synaptic vesicles
Neurotransmitter crosses the synapse
Taken up by postsynaptic receptor site on next neuron
Chemical message converted back to electrical impulse
Process of electrical transmission can begin

18
Q

How do the type of signals vary depending on where they are happening in the neuron?

A
Inside = electrical
Between = chemically
19
Q

What two effects can neurotransmitters have?

A

Excitatory and inhibitory

20
Q

Describe the excitatory effect of a neurotransmitter

A

Binds with postsynaptic receptor
causes electrical change in the membrane of that cell
results in excitatory post-synaptic potentional postsynaptic cell is more likely to fire

21
Q

Describe the inhibitory effect of a neurotransmitter

A

Binds with postsynaptic receptor causes
electrical change in the membrane of that cell
results in inhibitory post-synaptic potential
postsynaptic cell is more less to fire

22
Q

Describe the effect of summation

A

Excitatory and inhibitory influences summed
Must reach a certain threshold for the action potential for the post synaptic neuron to be triggered
If net effect of neurotransmitter is inhibitory then post synaptic neuron is less likely to fire, excitatory net effect, more likely to

23
Q

Describe the reflex arc

A

E.g. Knee-jerk reflex
Stimulus detected by sense organs in PNS
Conveys message along a sensory neuron
Message reaches CNS where it connects with a relay neuron
Transfers message to motor neuron
Carries message to effector which brings about the response