neuronal pigments/inclusions associated with disease Flashcards

1
Q

intranuclear inclusions seen in herpes simplex encephalitis

A

Cowdry type A

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2
Q

cytoplasmic inclusions diagnostic of rabies

A

Negri bodies

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3
Q

neuronal inclusions characteristic of parkinson disease

A

Lewy bodies

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4
Q

cytoplasmic inclusion bodies associated with aging

A

Lipofuscin granules

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5
Q

dark cytoplasmic pigment in neurons of substantia nigra and locus coeruleus, not seen in patients with Parkinson

A

melanin

Parkinson- loss of melanin (dopamine is a precursor)

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6
Q

eosinophilic, rod-like inclusions in hippocampus of Alzeihmer patient

A

Hirano bodies

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7
Q

diagnostic of Alzheimer disease

A

Neurofibrillary plaques + tangles

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8
Q

filamentous inclusions that stain with silver, don’t survive neuronal death

A

Pick bodies

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9
Q

filamentous inclusions that stain with PAS and ubiquitin

A

Lewy bodies

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