Neuronal communication Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

What are sensory receptors for? (2)

A

Detecting changes in its environment (1) and converting the stimulus into a nervous impulse (1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does it mean when sensory receptors are referred to as ‘transducers’? (1)

A

They convert stimuli into nervous impulses (1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Each sensory receptor is specific to a single type of stimulus. Describe the stimuli and an examplery sensory organ attached to each of these types of sensory receptors (8) :

  • Mechanorecptor
  • Chemoreceptor
  • Thermoreceptor
  • Photoreceptor
A
  • Mechanorecptor; pressure and movement, skin. (2)
  • Chemorecptor; chemicals, nose/tongue. (2)
  • Thermoreceptor; heat, tongue/skin. (2)
  • Photoreceptor; light, eyes. (2)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Order the following components (1) : relay neurone, effector, sensory neurone, motor neurone, receptor

A

Receptor -> sensory neurone -> relay neurone -> motor neurone -> effector (1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Schwann cells produce membranous layers that grow around the axon of neurones (myelin sheath). What is the purpose of this? (2)

How does it work? (2)

A

Acts as an insulating layer (1). Myelinated neurones conduct electrical impulses at a faster rate (1).

Works by gaps in the mylelin sheath called nodes of Ranvier (1). The electrical impulse ‘jumps’ from node to node (1).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The resting potential of an axon is -70mv. Describe how this is maintained. (6)

A
  • Sodium-potassium pumps (carrier proteins) are in the membranes of neurones. (1)
  • Pumps use ATP to actively transport 3 sodium ions out and 2 potassium ions in. (1)
  • More positive ions outside axon than inside/maintains electrochemical gradient. (1)
  • The membrane contains channel proteins that allow potassium and sodium ions to move through by facilitated diffusion. (1)
  • The protein channels are less permeable to sodium ions (1), resulting in potassium ions diffusing out (down the concentration gradient) at a faster rate than the diffusion of sodium ions into the axon. (1)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Fill in the blanks about producing an action potential (9) :

Stimuli cause ___ ion channels to open, allowing the ions to diffuse ___ the electrochemical gradient. Once the potential ___ has reached a certain threshold, the neurone is said to be de___ and an action potential is generated. As the inside of the axon becomes less ___, more channels open (___ feedback). Once the p.d has reached around 30mv the sodium ___-gated channel proteins close, while potassium channels open (___ feedback). As potassium ions diffuse out the axon and sodium ions are prevented from diffusing in, ___ occurs.

A
  • Sodium (1)
  • Down (1)
  • Difference (1)
  • Depolarised (1)
  • Negative (1)
  • Positive (1)
  • Voltage (1)
  • Negative (1)
  • Repolarisation (1)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Following repolarisation, potassium voltage-gated channels are slow to close. What does this result in?

A

Hyperpolarisation/the p.d becomes lower than the resting potential (1), as too many potassium ions diffuse out the axon (1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does ‘refractory period’ refer to? (2)

A

The period of time starting from repolarisation (1) and ending once the resting potential is established again (1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Describe the transmission of a nerve impulse along the axon. (3)

A
  • Depolarisation moves in one direction across the axon. (1)
  • Depolarisation of one section of the axon triggers sodium channels to open further down the axon. (1)
  • The previous section of the axon is in the repolarisation stage (sodium channels closedm potassium channels open). (1) This makes it unresponsive. (1)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the all or nothing principle? (2)

A

The stimulus must depolarise the receptors beyond the threshold level to trigger the sensory neurone to transmit a nervous impulse. (1)
No matter how strong the stimulus, the size of the action potential is the same (however, stimulus strength may affect frequency). (1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

State two purposes of the refractory period. (2)

A
  • Ensuring action potentials are discrete events/prevents them from merging. (1)
  • Prevents current from travelling backwards. (1)
  • Ensures that impulse travels in one direction. (1)
  • Determines the frequency at which impulses can be transmitted across an axon. (1)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Explain saltatory conduction. (4)

A
  • It is the transmission of nervous impulses in myelinated neurones. (1)
  • In the sections of the axon surrounded by a myelin sheath, depolarisation cannot occur. (1)
  • Action potentials only occur at the nodes of Ranvier. (1)
  • The attraction between sodium ions and the negative potential difference at the next node of Ranvier produces a localised electrical circuit. (1)
  • This induces the opening of sodium voltage-gated channels at the next node, causing the nervous impulse to ‘jump’. (1)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How does diameter of an axon affect the speed of conduction? (3)

How does temperature affect the speed of conduction? (2)

A
  • Thicker axons have a greater speed of conduction. (1)
  • The axon membrane has a larger surface area over which diffusion of ions can occur. (1)
  • Therefore, the rate at which action potentials and depolarisation occurs is higher. (1)
  • There is less electrical resistance in the cytoplasm of wider axons. (1)
  • Colder temperatures mean potassium and sodium ions have less kinetic energy in facilitated diffusion. (1)
  • Rate of diffusion, therefore, is slower. (1)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Define ‘synapse’. (1)

A

The junction where two neurones meet (1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What neurotransmitter do cholinergic synapses use? (1)

A

Acetylcholine (1)

17
Q

Fill in the blanks about synapses in neurotransmission (10) :

An electrical impulse arrives at the end of the ___ neurone, also referred to as the synaptic ___. The membrane becomes ___, causing calcium ion channels to open. The diffusion of calcium ions into the neurone causes ___ containing neurotransmitters to ___ with the presynaptic membrane. The neurotransmitters are released and diffuse across the ___ ___. The neurotransmitters bind to ___ molecules on the ____ membrane. This causes sodium ion channels to ___, leading to an action potential in the ___ neurone.

A
  • Presynaptic (1)
  • Knob (1)
  • Depolarised (1)
  • Vesicles (1)
  • Fuse (1)
  • Synaptic cleft (1)
  • Receptor (1)
  • Postsynaptic (1)
  • Open (1)
  • Postsynaptic (1)
18
Q

Why must neurotransmitters be destroyed/recycled? (1)

A

Prevents repeated impulses from continued stimulation of postsynaptic neurone. (1)

19
Q

Describe nervous transmission across a cholinergic synapse. (5)

A
  • Action potential arrives at end of presynpatic neurone/synaptic knob, depolarising the section. (1)
  • Voltage-gated calcium ion channels are stimulated to open. (1)
  • Calcium ions diffuse down the electrochemical gradient into the synaptic knob. (1)
  • Vesicles that contain acetylcholine (ACh) are triggered to fuse with the presynaptic membrane and release it into the synaptic cleft by exocytosis. (1)
  • ACh diffuses across synaptic cleft and binds to cholinergic receptors in the postsynaptic membrane. (1)
  • Sodium ion channels open, leading to the postsynaptic membrane becoming depolarised, inducing an action potential. (1)
20
Q

How do synapses prevent multi-way transmission? (1)

A
  • Neurotransmitters are only released from one side. (1)
21
Q

Explain the importance of summation (3)

A
  • Summation adds multiple impulses together. (1)
  • Enables a combination of different stimuli to trigger one response. (1)
  • If multiple nervous impulses arrive in quick succession (temporal summation), a larger amount of ACh is released into the synaptic cleft. (1)
  • If multiple nervous impulses arrive simultaneously at different synaptic knobs (spacial summation), a larger amount of ACh is released into the synaptic cleft. (1)
  • This means more sodium ion channels open in the postsynaptic membrane, making it easier to reach the threshold potential. (1)
22
Q

What are the differences between inhibitory and excitatory synapses? (4)

A

Inhibitory synapses release inhibitory neurotransmitters that prevent the generation of an action potential in the postsynaptic membrane. (1) They do this by causing potassium ion channels to open, causing hyperpolarisation. (1)

Excitatory synapses release excitatory neurotransmitters that stimulate the generation of an action potential in the postsynaptic membrane. (1)
They do this by causing sodium ion channels to open, causing depolarisation. (1)

23
Q
A