Neuromuscular Unit 3 Exam Flashcards
an alteration in brain function or evidence of brain pathology caused by external force
traumatic brain injury (TBI)
what are some common causes of TBI?
falls
firearm injuries
motor vehicle crashes
assaults
what is a common cause of TBI that accounts for nearly half of TBI related hospitalization?
falls
leading cause of injury related death and disability
TBI
TBI incidence is highest in older ______ followed by infants and young adults/adolescents
older adults (>75)
men are ______ as likely as women to be hospitalized following a TBI
2x
do men or women have a higher rate of TBI related deaths?
men
what is the pathophysiology of a TBI?
result of a high velocity or high impact hit to the head leading to brain tissue damage
2 categories of brain tissue damage
primary injury
secondary injury
what the two mechanisms of primary injuries of TBI?
direct contact with an object
rapid acceleration/deceleration
primary injury mechanism that leads to focal brain damage
direct contact
TBI due to direct contact is between what two things?
skull and penetrating object
what are the four common areas of primary injury that result from direct contact mechanisms?
anterior temporal poles
frontal poles
lateral inferior temporal cortices
orbital frontal cortices
primary injury mechanism that causes sheer, tensile, and compressive forces in the brain
rapid acceleration/deceleration
sheer, tensile, and compressive forces in the brain lead to what injury?
traumatic axonal injury (TAI)
what other injury can occur with a TAI that signifies a severe brain injury where not only the axons are damaged but also the functional regions of the cortex are disrupted, often leading to significant cognitive impairments and neurological deficits
cortical disruption
why are changes in the brain due to a TAI difficult to view on a MRI or CT scan?
they are microscopic
common areas of TAI occurrence in the brain
corpus callosum
internal capsule
cerebral peduncle
brainstem
cell death following brain tissue damage
secondary injury of TBI
what are some examples of secondary injuries of TBI?
hypoxemia
hypotension
ischemia
edema
elevated ICP
what is the pathophysiology of a secondary TBI injury?
brain tissue damage triggers a cellular cascade causing cell death
release of glutamate and other excitatory neurotransmitters lead to increased brain swelling and therefore increased _____
ICP
blood pooling in the brain following a head injury
hematoma
3 hematoma classifications
epidural
subdural
intracerebral
what causes ICP to elevate?
swelling in the brain is confined by the rigidity of the skull
injuries that result from lack of oxygen to the brain caused by anoxia, hypotension, and damage to vascular areas of the brain
hypoxic ischemic injuries
main goal of early medical management of a TBI
maintain blood flood and oxygen delivery to the brain to reduce the risk of secondary injury
normal systolic BP
> 90 mmHg
normal O2 sats
> 90%
______ spine stabilized until ligamentous and/or bony injury can be ruled out
cervical
normal cerebral perfusion pressure (CPP)
> 60 mmHg
normal intracranial pressure (ICP)
< 20 mmHg
3 ways to monitor ICP
external ventricular drain
subdural bolt
fiber optic catheter
ICP should be monitored for individuals with any of these four things
GCS less than 8
acute findings on CT scan
systolic BP < 90 mmHg
> 40 years of age
way to treat elevated ICP pharmacologically?
sedating medications
(example: Barbituates)
ways to treat an elevated ICP
HOB at 30 degrees
hypothermia
medically induced coma
surgical decompression
shunt placement
osmotherapy
imaging used initially following a TBI because it is fastest
CT scan
imaging used 24-48 hours following a TBI for higher sensitivity OR if initial scan was negative
MRI
3 neurosurgeries that may be needed for subdural hematomas or other lesions for ICP management
craniotomy
craniectomy
burr holes
removal of part of the skill bone with immediate replacement during the same surgery
craniotomy
a portion of the skull bone is removed and not immediately replaced
craniectomy
replacement surgery of the skull using the patient’s or other material such as titanium
cranioplasty
small holes are drilled in the skull to relieve pressure on the brain
burr holes
continued overactivity of the sympathetic nervous system following a TBI
paroxysmal sympathetic hyperactivity (PSH)
paroxysmal sympathetic hyperactivity (PSH) is also known as what?
sympathetic storming
% incidence of PSH
30%
symptoms of PSH
elevated HR, RR, and BP
diaphoresis
decerebrate/decorticate posturing
hypertonia
teeth grinding
abnormal development of bone
osteogenesis
abnormal development of bone in areas of soft tissue
heterotrophic ossification (HO)
HO most often occurs in what two joints?
hip and knee
clinically significant HO occurs in what percentage range of adult patients with TBI?
10-20%
individuals with _______ are at an increased risk of developing HO
spasticity
early symptoms of HO
swelling
ROM limitations
joint pain
redness/warmth
low grade fever
how can HO be managed pharmacologically?
NSAIDs
what limitation is important to address with physical therapy for patients with HO?
range of motion