Neuromuscular Transmission Flashcards
What is myasthenia gravies
Autoimmune disorder where the body produced antibodies that block or alter acetycholine rejectors at the neuromuscular junction
Impaired communication between nerve and muscle
Muscle wreak eSS which worsens with activity, improves with rest
Drooping eyelid and double vision
Dysphagia
What is lambert Eaton myasthenia syndrome
Autoimmune disorder, body attacks voltage gated calcium channels on the presynaptyic nerve terminal and NMJ
Reduces amount of acetylcholine release
Proximal muscle weakness
Dry mouth, ED, constipation
Muscle weakness improved with repetitive activity
Double vision
Cancer of the small cell lung
What is botulism
Toxin produced by a bacteria that inhibits the release of acteylcholine and NMJ, FLACCID PARALYSIS
Double vision
Dropping eyelids
Flaccid paralysis behind in face and moved down body
Dysphagia
Respiratory sucked weakness
No sensory affects
Contaminated foods wound infection
What is GBS
Autoimmune condition that affects peripheral nerves after an infection
Demyelination of peripheral nerve axons
Ascending weakness
Flaccid paralysis
Difficulty breathing
Cranial nerve involvement like facial weakness
What is polio
Virus affecting motor neurons in spinal cord and brainstem leading to paralysis
Childhood disease tho adults can be affected
Acute flaccid paralysis
Respiratory failure
Muscle atrophy
