Neuromuscular System & Exercise Flashcards

1
Q

What is a brain neurotransmitter

A
  • chemical messenger that diffuse across the synapse to combine with a targeted receptor molecule on the postsynaptic membrane to facilitate depolarization or hyperpolarization
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2
Q

What does the peripheral nervous system include

A
  • afferent nerves that relay sensory information from muscles, joints, skin, & bones toward the brain
  • efferent nerves that transmit information away from the brain to glands & muscles
  • somatic & autonomic nervous systems
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3
Q

What does the somatic nervous system do

A
  • innervates skeletal muscle
  • somatic efferent nerve firing excites muscle activation
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4
Q

What does the autonomic nervous system do

A
  • innervates smooth muscle in intestines, sweat & salivary glands, myocardium, & some endocrine glands
  • includes the sympathetic & parasympathetic nervous systems
  • sympathetic nerve fibers mediate excitation
  • parasympathetic activation inhibits excitation
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5
Q

What does the sympathetic nervous system supply & do

A
  • supplies the heart, smooth muscle, sweat glands, & viscera
  • excitation occurs during fight-or-flight situations that require whole body arousal for emergencies
  • accelerates breathing & heart rate, pupils dilate, & blood flows from the skin to deeper tissues
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6
Q

What does the parasympathetic nervous system supply & do

A
  • supplies the thorax, abdomen, & pelvic regions
  • releases acetylcholine
  • the postganglionic parasympathetic nerve fibers produce effects opposite of sympathetic fibers
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7
Q

What does a motor unit consist of

A
  • cell body houses the control center
  • axon extends from the cord & delivers an impulse to the muscle fibers it innervates
  • dendrites receive impulses through spinal cord connections & conduct them toward the cell body
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8
Q

What allows for higher transmission velocity in a motor unit

A
  • nodes of ranvier
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9
Q

What encases the bare axon of a motor unit

A
  • Schwann cells in the peripheral nervous system encase the bare axon & then spiral around it
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10
Q

Describe the roles of the neuromuscular junction/motor end plate

A
  • provides interface b/w the end of a myelinated motoneuron & a muscle fiber
  • functions to transmit nerve impulses to muscle fibers
  • presynaptic terminals lie close to with the sarcolemma
  • synaptic cleft is the region where neural impulse transmission occurs
  • excitation occurs at the neuromuscular junction
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11
Q

What is the all-or-none principle

A
  • if a stimulus triggers an action potential in the motoneuron then all of the accompanying muscle fibers contract synchronously
  • once the neuron fires & the impulse reaches the neuromuscular junction, the muscle cells always contract to the fullest extent
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12
Q

What is gradation of force principle

A
  • the force of muscle action varies from slight to maximal in one of two mechanisms
  • increasing the number of motor units recruited
  • increasing the frequency of motor unit discharge (to create a summation of muscle contraction)
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13
Q

What is motor unit recruitment & size principle

A

Motor unit recruitment: the process of adding motor units to increase muscle force
Size principle: motoneurons with larger axons become recruited as muscle force increases

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14
Q

What provides the mechanism to produce the desired coordinated response

A
  • selective recruitment & firing pattern of the fast-twitch & slow-twitch motor units that control movement
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15
Q

Define neuromuscular fatigability

A
  • the decline in muscle tension or force capacity with repeated stimulation during a given time period
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16
Q

What factors decrease the force-generating capacity

A
  • exercise induced alterations in levels of CNS neurotransmitters serotonin, 5-hyroxytryptamine, dopamine, & ACh
  • reduced glycogen content in active muscle fibers during prolonged exercise
  • increased level of blood & muscle lactate
  • fatigue at the neuromuscular junction
17
Q

Describe proprioceptors

A
  • specialized sensory receptors sensitive to stretch, tension, & pressure in the muscles, joints, & tendon
  • allows continual monitoring of the progress of any movement or sequence of movements
18
Q

Describe muscle spindles

A
  • they provide mechanic-sensory information about changes in muscle fiber length & tension
  • primarily respond to muscle stretch through reflex action by initiating a stronger muscle action to counteract the stretch
19
Q

Describe the stretch reflex

A
  • muscle spindle responds to stretch
  • afferent nerve fiber carries sensory impulse from the spindle to the spinal cord
  • efferent spinal cord motor neuron activates the stretched muscle fibers
20
Q

Describe Golgi tendon organs (GTOs) & their function

A
  • located in ligaments of joints to primarily detect differences in muscle tension
  • protect muscle & its connective tissue harness from injury by sudden excessive load or stretch
21
Q

Describe pacinian corpuscles & their function

A
  • found in the subcutaneous tissue on the nerves of the sole of the foot, palm of the hand, mucous membranes, genital organs, & in close proximity with the nerves of joints
  • they respond to quick movement & deep pressure
22
Q

Describe the purpose of skeletal muscle capillarization

A
  • capillary microcirculation expedites removal of heat & metabolic byproducts from active tissues
  • provides a large surface area to exchange metabolically generated heat, fluids, electrolytes, gases, & macromolecules
23
Q

What is the functional unit of movement

A
  • the motor unit
24
Q

What is the functional unit of the muscle cell

A
  • the sarcomere
25
Q

Define the H band of a sarcomere

A
  • area of the sarcomere that only contains myosin
26
Q

Define the I band of a sarcomere

A
  • area of a sarcomere that only contains actin
27
Q

Define the A band of a sarcomere

A
  • area of the sarcomere that contains the overlap of actin & myosin
28
Q

Define the Z line of a sarcomere

A
  • it’s the zig-zag line at the end of the sarcomere
29
Q

Define the M line of the sarcomere

A
  • it’s the line in the very middle of the sarcomere
30
Q

What happens to the different bands when the sarcomere contracts

A
  • H band/zone decreases
  • A band increases
  • I band decreases
31
Q

Describe the steps of the sliding filament theory

A
  • tropomyosin covers the binding sites for myosin to attach to the actin
  • calcium binds to the troponin complex which opens the myosin binding sites
  • myosin attaches to the actin
  • ATP is used to detach the myosin heads from the actin
32
Q

Characteristics of fast-twitch muscle fibers

A
  • rapidly transmit action potentials
  • high activity level of myosin ATPase
  • rapid rate of calcium release & uptake by the sarcoplasmic reticulum
  • generate rapid crossbridge turnover
33
Q

Describe Type I fibers

A
  • generate energy for ATP resynthesis predominantly by aerobic energy transfer
  • possess a low activity level of myosin ATPase
  • resist fatigue & power prolonged aerobic exercise
  • slow oxidative fibers
  • max duration of use is hours for aerobic activity
  • slow twitch fiber/hard to fatigue
34
Q

Describe Type IIa fibers

A
  • exhibits fast shortening speed & moderately well-developed capacity for energy transfer from both aerobic & anaerobic sources
  • represents the fast oxidative glycolytic fibers
  • max duration of use is <30 minutes for long term anaerobic activity
  • moderately fast twitch fiber/fairly hard to fatigue
35
Q

Describe Type Ilx fibers

A
  • possess the greatest anaerobic potential & most rapid shortening velocity
  • represents the fast glycolytic fiber
  • max duration of use is <5 minutes for short term anaerobic activity
  • fast twitch fiber/less hard to fatigue
36
Q

Describe muscle fiber type distribution differences

A
  • genetic code largely determines a person’s predominant fiber type
  • specific exercise training improves the metabolic capacity (ability for the body to uptake O2/VO2 max) of each fiber type but you can not create more of any fiber types