Neurology Embryology Flashcards

1
Q

the notocord induces overlying ________to differentiate into neuroectoderm and form the neural plate

A

ectoderm

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2
Q

the neural plate gives rise to

A

neural tube and neural crest cells

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3
Q

alar plate is

A

sensory (DORSAL) think of DRG

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4
Q

the basal plate is

A

motor (ventral)

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5
Q

what does the notochord become

A

nucleus pulposis of the intervertebral disks in adults

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6
Q

telencephalon gives rise to

A

cerebral hemispheres and lateral ventricles

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7
Q

diencephalon gives rise to

A

thalamus and third ventricle

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8
Q

mesencephalon gives rise to

A

mid brain and aqueduct

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9
Q

metencephalong gives rise to

A

pons, cerebellum, and upper part of the fourth ventricle

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10
Q

myelencephalon gives rise to

A

medulla and LOWER part of the fourth ventricle

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11
Q

mid brain is also called

A

mesencephalon

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12
Q

hind brain is also called the ____-and consists of the _______and ___________

A

metencephalon, myelencephlon

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13
Q

the forebrain is also called

A

prosencephalon

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14
Q

the prosencephlong gives rise to

A

telencephalon and diencephalon

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15
Q

the neural crest cells give rise to

A

PNS neurons and schwann cells

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16
Q

mesoderm gives rise to what parts of CNS/PNS

A

microglia

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17
Q

the neuroectoderm gives rise to what

A

CNS neurons, ependymal cells, oligodendroglia and astrocytes

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18
Q

neuroectoderm for ________and neural crest for ________

19
Q

when time period do the neuralpores close

20
Q

when alpha fetoprotein (AFP) is elevated what should you be thinking

A

neural tube defect

21
Q

when alpha fetoprotein (AFP) is elevated and then you find they also have elevated acetylcholinesterase then what do you highly suspect with great accuracy

A

neural tube defect

22
Q

low folic acid intake is assoc with

A

neural tube defects

23
Q

associated with a tuft of hair or skin dimple at the level of bony defect

A

spina bifida occulta

24
Q

meninges but NOT the spinal cord herniate through the spinal canal defect, normal AFP

A

meningocele

25
meninges AND spinal cord herniate through the spinal canal defect
meningomyelocele
26
malformation of the anterior neural tube resulting in NO forebrain, open calvarium
anencephaly
27
what are the clinical findings in anencephaly
increased AFP, polyhydramnios, assoc with maternal diabetes type 1 and maternal folate supplementation helps to decreased risk
28
what is holoprosencephaly
failure of the left and the right hemispheres to separate' usually weeks 5-6
29
what is the mutations associated with holoprosencephaly
sonic hedgehock signaling patways
30
what is arnold chiariri malforamtion
signiciant herniation of cerebellar tonsils and vermis through the foramen magnum with aqueduct stenosis and hydrocephalus which often presents with lumbosacral myelomeningocele and paralysis below the defect
31
what are the clinical associations with dandy walker syndrome
hydrocephalus and spinabifida
32
what is dandy walker syndrome
agenesis of cerebellar vermis with cystic enlargement of the 4th ventricle (fills the enlarged posterior fossa)
33
a cystic cavity (syrinx) within the spinal cord)
syringomyelia
34
what is the loss from a syringomyelia
cape-like bilateral loss of pain and temperature sensation in the UPPER extremities but FINE touch sensation is preserved
35
where is the most common region for a syringomyelia
C8-T1
36
what is syringomyelia associated with
chiari 1 malformation
37
what arches help contribut to the tongue innervation
1st and 2nd branchial arches
38
sensation to tongue anterior 2/3
CN V3
39
tast to anterior 2/3
Cn VII
40
3rd and 4th branchial arches help innervate and sensate the
posterior 1/3 of tonugue ( Cn IX, and X)
41
muscles of the tongue are derived from
occipital myotomes
42
the taste receptors synapse in what nucleus
solitary nucleus
43
nerves responsible for pain to the tongue
CN V3, IX, and X