neurology Flashcards

1
Q

a 47 yo IVDU comes in requesting hydromorphone for back pain. His pain is worse w/ valsalva and his L4 vertebra is TTP. His LE have 4-/5 strength bilaterally, his has flaccid rectal tone and plantar response if upgoing… next best step?

if same clinical picture in a patient w/ hx of prostate ca… next best step?

A

MRI of the spine. 2nd choice is CT myelogram

if the same clinical picture in a patient w/ hx of prostate ca… next best step? IV dexamethasone then MRI then radiation therapy

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2
Q

Pt s/p MCV w/ whiplash has loss of pain/temp on neck and arms + intact sensation

A

syringomelia. MRI to dx, surgery to tx

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3
Q

Pt w/ high cholesterol presents w/ acute onset flaccid paralysis below the waist, loss of pain/temp w/ preserved vibration of position

A

anterior spinal artery occlusion

tx- supportive

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4
Q

most common cause of stroke? best 1st step? most accurate test? treatment if w/in 3-4.5 hr? tx if later than 4.5hr? CI ? tx if stroke on aspirin? tx for subarachnoid hemorrhage?

A

most common cause of stroke- 80% ischemic, 20% hemorrhagic
best 1st step- non contrast CT to r/o hemorrhage
most accurate test- diffusion weighted MRI for ischemic. CT can be neg 1st 48 hrs
treatment if w/in 3-4.5 hr- TPA
tx if later than 4.5hr- aspirin. heparin only for those in a-fib, basilar clot
CI - stroke w/in 3 mo, surg w/in 2 wek, LP w/ 1 wk
tx if stroke on aspirin- add dipyridamole or switch to clopidorgel. do not use ticlopidine
tx for subarachnoid hemorrhage- nimodipine to reduce ischemic stroke from Vasoconstriction (MC cause of M&M)

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5
Q

when to clip an aneurysm?

A

w/ in days or rupture or when <10mm

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6
Q

when to do endarterectomy?

A

when occlusion >70% and is symptomatic (>60% if >60 yo)

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7
Q

total paralysis except for vertical eye movements

A

paramedial branches of basilar artery

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8
Q

Vertigo, vomiting, nystagmus, and clumsiness with the right arm

A

major R cerebellar arteries

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9
Q

L hemisensory loss + horners + R facial sensory loss

A

R wallenburg (RCA)

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10
Q

falling to the L + R ptosis + eye deviated to the right and down

A

R Benedikt’s

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11
Q

L hemiplegia +R ptosis + eye deviated to the right and down

A

R Webbers

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12
Q

L hemiplegia/hemisensory loss in the leg>arm. confusion, behaviroal disturbance

A

R ACA stroke

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13
Q

L hemiplegia/hemisensory loss, L homonomous hemianopsia w/eyes deviated towards the R + apraxia

A

R MCA stroke

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14
Q

status epilepticus tx

A

loraxepam + LD of phenytoin. then phenobarbital then anesthesia

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15
Q

partial seizures begin focally (arm twitch, de ja vu, burning rubber smell)

tx?

A

simple if no LOC and complex if LOC (may have lip smacking) both can generalize

tx- carbamazepine or phenytoin. then valporate or lamotrigine

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16
Q

generalized seizures begin from both hemispheres @ once

tx. for kiddos
tx for alduties?

A

either grand mal or absence (5-10sec unresponsivenss in kiddos),myoclonic, atonic

tx. for kiddos- absence- ethosuximide
tx for alduties- valproic acid, then lamotrigine, carbamezepine, phenytoin

17
Q

3 hz spike and wave

A

absence seizures

tx w/ ethosuxamide

18
Q

triphasic bursts

A

creutzfeldt Jakob. dementia and myoclonus

19
Q

Diffuse background slowing

A

delirium. contrast w/ psychosis that has no EEG changes

20
Q

Hypsarrhythmia

A

infantile spasms. tx w/ ACTH

most are associated with mental retardation

21
Q

worse headache of my life… first step

A

subarachnoid hemorrhage…noncontrast CT

22
Q

new onset severe headche + fever and nuchal rigidity… first step

A

meningitis. abx then CT then LP

23
Q

new onset severe headche + deep pain that wakes up at night. worse w/ coughing or bending forwards

A

consideer brain tumor. most important prognostic factor is grade (degree of anaplasia)

24
Q

new onset severe headche + unilateral pounding headache w/ changes in vision and jaw claudication… what to do?

A

temporal arteritis… Check EXR + give streoids then do temporal artery biopsy. can lead to blindness

25
Q

new onset severe headche + fat lady on minocycline ow how takes isotreintoin w/ abducens nerve palsy/diplopia

A

pseudomoto cerebry. also assoc. w/ OCPs. normal CT, elevated pressure on LP.

Tx- weight loss then acetazolamide then shunt ot optic nerve sheath fenestration

26
Q

diarrhea 3wks ago, now areflexia and ascending paralysis? most likely bug? best tx?

A

Guillain-barre- CFS shows albumino-cytolotic dissociation

bug- campylobacter, HHV, CMV, EBV
best tx- IVIG or plasmapheresis. monitor VC for intubation req

27
Q

nasal voice, ptosis, dysphagia, resp. acidosis… 1st test? Most accurate test?acute tx? chronic tx? meds to avoid?

A

Myasthenia Gravis
1st test- Ach-ab/
most accurate- EMG:decrease in muscle fibers contraction
acute tx-IVIG or plasmapheresis. monitor VC for intubation req
chronic tx-pyridostigmine, GCs/AZA, thymectomy (<60)
meds to avoid- aminoglycosides and beta blockers

28
Q

urinary retention, babinski on R. episode of double vision 6mo ago… best dx test? acute tx? chronic tx?

A

Multiple slcerosis- neuro-deficits separated by time and space
best dx test- MRI of the brain. incr T2 @ periventricular white matter
acute tx- steroids (3 days IV then 4wks oral) plasma exchange is second in line
chronic tx- IFN-beta1b, glatiramer reduces exacerbations