Neurology Flashcards

1
Q

what is carotid disease caused by?

A

atherosclerosis

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2
Q

what’s a major cause of stroke?

A

carotid disease

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3
Q

what’s the most common location of emboli causing CVA?

A

carotid bifurcation

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4
Q

what’s the RFs for carotid disease?

A

h/o TIA, HTN, high cholesterol, DM, age, obesity, sleep apnea, lack of exercise

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5
Q

what are sx’s of carotid disease?

A

maybe TIAs & CVAs

carotid bruits (“cervical bruit), Hollenhorst plaques (small, yellow particles on retinal vessel)

can be asx

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6
Q

what is the classic finding in a pt with carotid stenosis?

A

cervical bruit (high-pitched systolic murmur)

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7
Q

what’s the GOLD STANDARD dx for carotid artery disease?

A

CTA

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8
Q

what imaging can you do to dx carotid artery disease?

A

Doppler U/S to evaluate blood flow

CTA = definitive study & gold standard

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9
Q

what’s the tx for carotid artery disease?

A

Meds: low dose ASA & statin

Surgery: Carotid endarterectomy OR Carotid angioplasty & stenting

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10
Q

when is Carotid endarterectomy indicated for tx?

A

if pt has 70-99% occlusion & if peri-op morbidity & mortality risk is <6% & easily surgical

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11
Q

when is carotid stenting done?

A

for pts w/ carotid lesion w/ poor surgical accessibility, previous endarterectomy, or other concerning comorbidities

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12
Q

what kind of bleed is a subarachnoid hemorrhage and what’s the location? what’d it due to?

A

arterial bleed b/w arachnoid & Pia mater in subarachnoid space

d/t rupture of an intracranial aneurysm (MC saccular “berry” aneurysms)

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13
Q

what are the MC causes of subarachnoid hemorrhage?

A

MCC = berry aneurysm rupture, AVM

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14
Q

what are risk factors for subarachnoid hemorrhage?

A

fam hx, smoking, HTN, heavy drinking, h/o AVM

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15
Q

what are the s/s of a subarachnoid hemorrhage

A

SUDDEN THUNDERCLAP HEADACHE “WORST HA OF MY LIFE”

Meningeal sx’s: stiff neck, photophobia, delirium

No focal neurologic deficits (usu.)

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16
Q

how do you dx a subarachnoid hemorrhage?

A

CT performed first
-If CT negative -> LP: xanthochromia (RBC’s), incr. CSF pressure

CTA (performed after initial dx w/CT)
-if negative then do MRA

17
Q

what’s the first dx imaging test for subarachnoid hemorrhage?

18
Q

what does LP for subarachnoid hemorrhage show?

A

xanthochromia (Hgb breakdown), increased CSF pressure

19
Q

what’s the tx for subarachnoid hemorrhage?

A

surgical clipping or endovascular coiling of rupture aneurysm

Supportive: bed rest, lower ICP

Admin Nicardipine*, Nimodipine -> lower BP gradually

***ALWAYS RE-IMAGE HEAD AFTER TX

20
Q

what should be done after tx of subarachnoid hemorrhage?

A

re-imaging of head

21
Q

what’s the MC arterial bleed?

A

epidural hematoma (hemorrhage)

22
Q

where does epidural hematoma occur?

A

b/w skull & dura

23
Q

what’s the MC mechanism of an epidural hematoma?

A

Temporal bone fracture -> middle meningeal artery lacerated

24
Q

what artery is MC ruptured in epidural hematoma?

A

middle meningeal artery

25
what are the s/s of epidural hematoma?
brief loss of consciousness at the time of injury, followed by a normal mental status that progressively decreases over time as the hematoma expands
26
how do you dx epidural hematoma?
CT -> CONVEX (LENS-SHAPED) BLEED (the separation of the dura mater from the skull) Does NOT cross suture lines and usu. in TEMPORAL AREA
27
what is seen on CT for dx of epidural hematoma?
CONVEX (LENS-SHAPED) BLEED usu. in temporal area
28
what area is epidural hematoma usually in?
temporal area (b/c that's where middle meningeal artery is located)
29
what's the tx for an epidural hematoma?
observation if small Limit incr. ICP - keep HOB elevated and pt in neural position - sedation - removal of CSF IVFs, monitor for seizures surgical evacuation of hematoma
30
what's the MC venous bleed?
subdural hematoma (hemorrhage)
31
what's the location of a subdural hematoma? d/t what?
b/w dura mater and brain d/t tearing of cortical bridging veins
32
who is subdural hematoma MC in?
elderly or alcohol abuse
33
what's the MC cause of subdural hematoma?
blunt trauma (often causes bleeding on other side of injury "contra-coup")
34
what type of bleed is subdural hematoma?
MC venous bleed
35
what's the s/s of subdural hematoma?
varies, may have focal neuro sx
36
how do you dx subdural hematoma?
CT: concave (crescent-shaped) bleed ***Bleeding CAN cross suture lines (vs epidural can't)
37
what is seen on CT for dx of subdural hematoma?
concave (crescent-shaped) bleed
38
what's the tx of subdural hematoma?
hematoma evacuation vs supportive evacuation if massive or >/= 5mm midline shift
39
what's Amaurosis fugax?
transient monocular blindness d/t emboli in the ophthalmic artery