Neurology Flashcards
Ganglia
Collections of nerve cell bodies outside the CNS
Nuclei
Collection of nerve cell bodies with a similar function in the CNS
Synapses
Chemical = NT = 1-way
Electrical = gap junctions = 2-way
Chemical synapses depend on which electrolyte
Calcium: voltage-gated Ca channels
NT receptor types
Ionotropic receptors - directly gate ion channels.
Metabotropic receptors - 2nd messenger system: ion channels, cAMP activation, IC enzyme activation, gene transcription activation
In an electrical synapse what ions are moved to create the membrane potential
Na, K, Cl
What is the rmp of electrical synapses?
Spinal motor neuron: -65mV
Peripheral n fibers: -90mV
What results in an excitatory pre-synaptic potential (EPSP)?
Na influx
What results in an inhibitory post-synaptic potential (IPSP)?
Cl influx. K efflux.
Rapidly acting NT
Acetylcholine
Norepinephrine
Epinephrine
Gamma-aminobutyric acid (GABA)
Glycine
Glutamate
Nitric oxide