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bpt > Neurology > Flashcards

Neurology Flashcards

1
Q

Phenytoin - indications + AE

A

Focal sezuires
Common: sedation, tremor, ataxia, dizziness, headache, bradycardia, hypotension, asystole, vertical nystagmus
Serious: SJS, gingival hyperplasia, peripheral neuropathy, pancytopenia, osteoporosis, hepatotoxicity

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2
Q

Valproate - indications + AE

A

Generalised seizures
Common: sedation, tremor, ataxia, dizziness, headache, weight gain, hair loss, PCOS, parkinsonians with dementia
Serious: pancytopenia, osteoporosis, hepatotoxicity, pancreatitis, hyperammonemia

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3
Q

Carbamazapine - indications + AE

A

Focal seizures
Common: Sedation, nausea, ataxia, tremor, diplopia, dizziness
Serious: Hyponatraemia, SJS, pancytopenia, osteoporosis, hepatotoxicity, agranulocytosis

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4
Q

Lamotrigine - indications + AE

A

Focal/generalised seizures, pregnancy (**not myoclonic), older patients
Common: Sedation, nausea, ataxia, tremor, diplopia, dizziness, insomnia
Serious: SJS

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5
Q

Gabapentin/pregabalin - indications + AE

A

Focal seizures

Common: Sedation, weight gain, oedema, dizziness

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6
Q

Topiramate - indications + AE

A

Broad spectrum
Common: Sedation, nausea, ataxia, tremor, diplopia, dizziness, poor concentration, paraesthesia, weight loss, anhidrosis, dizziness
Serious: Nephrolithiasis (calcium phosphate), glaucoma, psychosis

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7
Q

Levetiracetam - indications + AE

A

Broad spectrum - focal/generalised seizures, pregnancy, older patients
Common: Sedation, irritability, psychosis, depression
Serious: suicidal ideation and thrombocytopenia (rare)

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8
Q

Lacosamide - indications + AE

A

Focal serizures
Common: Sedation, nausea, ataxia, tremor, diplopia, dizziness, PR prolongation
Serious: AV block, AF

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9
Q

Ethosuximide - indications + AE

A

Absent seizures

Serious: SJS, agranulocytosis, sleep disturbance

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10
Q

Status epilepticus treatment

A

IV benzodiapine + IV AEDs (IV phosphenytoin - IV valproac acid in patients allergic to phenytoin) or IV levetiracetam)

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