Neurologie

Question 0

Amantadin

Answer 0

Antiparkinsonikum
Antagonista NMDA glut. rec. 
zvysuje uvolnovani dopaminu, 5-HT
inhibitor MAO-A
Inhibuje reuptake
Anticholinergni ucinek

Question 1

Alteplasa

Answer 1

Akutni terapie CMP
Tkanovy aktivator plasminogenu
Podat co nejdrive

Question 2

Atropin

Answer 2

Lecba srdecni zastavy

Ocni lekarstvi - mydriatikum, cykloplegikum

Question 3

Baclofen

Answer 3

Centralni myorelaxans
Agonista presynaptickych GABA B rec.
Terapie spasticit u RS

Question 4

Benserazid

Answer 4

Antiparkinsonikum

Levodopa + inhibitor periferni dekarboxylazy

Question 5

Bezatropin

Answer 5

Antiparkinsonikum

Anticholinergikum

Question 6

Biperiden

Answer 6

Antiparkinsonikum

Anticholinergikum

Question 7

Karbidopa

Answer 7

Antiparkinsonikum

Levodopa + inh. Periferni dekarboxylazy

Question 8

Levodopa

Answer 8

Antiparkinsonikum

50-800 mg

Question 9

Ropinirol

Answer 9

Antiparkinsonikum

Selektivni agonista D

Question 10

Selegilin

Answer 10

Antiparkinsonikum

Ireverzibilni inhibitor MAO-B

Question 11

Tolkapon

Answer 11

Antiparkinsonikum

Inihibitor KOMT

Question 12

Donepezil

Answer 12

Kognitivum u AD

Inhibitor AChE

Question 13

Rivastigmin

Answer 13

Kognitivum u AD

Inhibitor AChE

Question 14

Galantamin

Answer 14

Kognitivum u AD

Inhibitor AChE

Question 15

Memantin

Answer 15

Kognitivum u AD

Nekompetitivni antagonista NMDA

Question 16

Lecithin

Answer 16

AD

Prekurzor ACh

Question 17

Pilokarpin

Answer 17

AD, glaukom
Agonista AChR
Miotikum pri lecbe glaukomu

Question 18

Methylprednisolon

Answer 18

Aktivni RS

I.v. 3 g

Question 19

Interferon

Answer 19

Chorobu modifikujici lecba RS
Beta 1A + 1B
Sy podobne chripce, hepatotoxicita

Question 20

Natalizumab

Answer 20

Chorobu midifikujici lecba RS
Monoklonalni protilatka
Selektivni imunosupresivum
Nereagujici relabujici-remitujici RS

Question 21

Tizanidin

Answer 21

Centralni myorelaxans
Lecba spasticity u RS
Alfa 2 agonista

Question 22

Tetrazepam

Answer 22

Centralni myorelaxans
Lecba spasticity u RS
Agonista GABA A

Question 23

Carbamazepin

Answer 23

Antiepileptikum
Na+
4-12 mg/l
Nauzena, poruchy visu
Agranulocytoza, aplasticka anemie

Question 24

Fenytoin

Answer 24

Antiepileptikun
Na+, Ca 2+, K+
Ataxie, nystagmus
Kognitivni poruchy
Hirsutismus
Gingivalni hyperplasie
Fetalni hydantoinovy syndrom

Question 25

Lamotrigin

Answer 25

Antiepileptikum
Na+
Vertigo, bolest hlavy…

Question 26

Topiramat

Answer 26

Antiepileptikum
Na+
Somnolence, unava,…

Question 27

Valproat

Answer 27

Antiepileptikum
Na+
Blok reuptaku GABA
Hepatotxicita
Spina bifida

Question 28

Vigabatrin

Answer 28

Antiepileptikum

Ireverzibipni blok GABA transferazy

Question 29

Phenobarbital

Answer 29

Antiepileptikum

Prodlouzeni doby otevreni Cl- kanalu (GABA)

Question 30

Clonazepam

Answer 30

Antiepileptikum

Zvysuje frekvenci otevirani Cl- kanalu (GABA)

Question 31

Diazepam

Answer 31

Antiepileptikum
Febrilni krece
Zvysuje frekvenci otevirani Cl- kanalu

Question 32

Etosuximid

Answer 32

Antiepileptikum

V oblasti thalamu blok napetove ovladanych Ca 2+ kanalu T-typu (NRT)

Question 33

Gabapentin

Answer 33

Antiepileptikum
Strukturni analog GABA, neinteraguje s rec.
Vazba na podjednotku napetove rizenych Ca kanalu - omezeny influx
Silnejsi nez pregabalin

Question 34

Pregabalin

Answer 34

Antiepileptikum
Strukturni analog GABA, nevaze se na rec.
Na podjednotku napetove rizenych Ca kanalu - omezuje influx Ca

Question 35

Ziconotid

Answer 35

Antiepileptikum

Analgetikum - neurogenni bolest

Question 36

Primidon

Answer 36

Antiepileptikum

Question 37

Zolpidem

Answer 37

Hypnotikum 3. generace

Polocas 2 hodiny