Neurological System Pt. 2 Flashcards

Myasthenia gravis, Guillain-Barre Syndrome, Multiple Sclerosis, Epilepsy, Parkinson's Disease

1
Q

What is a stroke?

A

Disruption of the blood supply to an area of the brain resulting in tissue necrosis and sudden loss of brain function.

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2
Q

Ischemic stroke

A

Blood supply to an area of the brain is reduced resulting in ischemia.

Causes include embolism and thrombosis

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3
Q

Hemorrhagic stroke

A

occurs secondary to rupture of a blood vessel often associated with hypertension

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4
Q

Transient Ischemic Attack

A

Brief episode, less than 24 hours. Resolves within 30 - 60 mins. Warning of impending stroke.

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5
Q

Hemiplegia

A

Paralysis of one side of the body

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6
Q

Hemiparesis

A

Weakness of one side of the body

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7
Q

Aphasia

A

loss of inability to comprehend or express speech

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8
Q

Hemianopsia

A

Blindness in half of the vision field

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9
Q

Agnosia

A

Loss of the ability to recognize objects

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10
Q

How long do you have to give TPA to a stroke patient?

A

3 hours from stroke onset.

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11
Q

Nursing mangement of acute phase of stroke

A

1) Maintain a patent airway and administer O2 as prescribed.
2) Monitor V/S
3) Suction secretions to prevent aspiration but never nasally or longer than 10 secs.
4) Monitor for  ICP
5) Position the client on the side to prevent aspiration with the HOB elevated to 15 - 30°
6) Monitor LOC, pupillary response, motor and sensory response, cranial nerve function, and reflexes.
7) Maintain a quiet environment.
8) Insert a urinary cath as prescribed
9) Administer IVF as prescribed
10) Maintain fluid and electrolyte balance

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12
Q

Nursing mangement of post-acute phase of stroke

A

1) Position on the unaffected side for 2 hours and 20 minutes on the affected side; prone may also be prescribed
2) Provide mouth, skin and eye care
3) Monitor gag reflex and ability to swallow
4) Perform ROM exercises to prevent contractures
5) Place TED stocking on the client
6) Provide sips of fluids and slowly advance to solids.
7) Provie soft and semi-soft foods, thicken fluids for better toleration.

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13
Q

Myasthenia Gravis

A

Autoimmune disease which results from antibodies blocking/destroying acetylcholine at the junction between nerves and muscle.

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14
Q

What test is done to dx Myasthenia Gravis

A

Positive Tensilon Test - Edrophonium Chloride administration resulting in alleviation of symptoms.

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15
Q

A patient arrives to AED presenting with diplopia, ptosis and dysphagia. She gave a positive result on the Tensilon Test. What first line medication would she be given?

A

Pyridostigmine Bromide (acetylcholinesterase inhibitor)

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16
Q

On your rounds you recognize the patient in bed 4 has a B/P 97/49 mmHg, nausea, vomitting and diarrhea. On further assesment Tensolin has no effect. What do these symptoms represent?

A

Cholingeric Crisis

Occurs due to overmedication, Rest + Digest.

17
Q

You observe that James with Myasthenia Gravias exhibits a low urine output and bowel incontinence. Further investigations shows that his V/S were HR 110 bpm, RR 26 bpm and B/P 130/59 mmHg. What do these symptoms represent?

A

Myasthenic Crisis

Occurs due to overmedication and is a flight-or-fight response

Exacerbation characterized by severe generalized muscle weakness and respiratory weakness that may result in respiratory faiilure

18
Q

Guillain-Barre Syndrome

A

Autoimmune attack on myelin sheath of peripheral nerves resulting in demyelination and some craniel nerves leading to hyporeflexia, parestheia and ascending weakness with dyskinesia.

19
Q

Ataxia

A

poor muscle control that causes clumsy movements.

20
Q

Medical management

A

1) Administer TPE & IVIG which directly affects myeline antibody level
2) Provide respiratory therapy or mechanical ventilation
3) ECG monitoring
4) Alpha-adrenergic blocking agents
5) Anticoagulant agents

21
Q

Multiple Sclerosis

A

Progressive demyelinating disease of CNS

Immune-mediated

22
Q

Relapsing-remitting MS

A

Clearly, acute attacks with full recover or residual deficit with recovery

23
Q

Beta-Interferons

Multiple Sclerosis

A

Decreases no. of relapses of symptoms by decreasing inflammation & immune system’s response

Decreases WBC’s

e.g., Avonex

24
Q

What would ordered if patient has a relapse of MS?

A

Methylprednisolone IV

25
Q

Given to MS patients with bladder dysfunction

A

Oxybutynin by relaxing bladder muscles to prevent contractions

26
Q

Kim has multiple sclerosis and complained of issues emptying her bladder. What medication would the nurse expect to be prescribed.

A

Bethanecol

27
Q

Frank experiences fatigue attributed to Multiple Sclerosis? What medication is given for this symptom?

A

Amantadine

28
Q

Margaret has Multiple Sclerosis. During an exacerbation, she experiences muscle spasms. To improve spasticity, what medication would be given?

A

Baclofen, skeletal muscle relaxant
or
Diazepam (Valium)

29
Q

What drug masks tremors in MS?

A

Propanolol

30
Q

Seizure

A

Abnormal electrical signals are being rapidly fired by neurons in the brain.

31
Q

Epilepsy

A

Defined as a group of syndromes characterized by unprovoked reccurent seizures.

32
Q

What drug causes enlarged and bleeding gums, used to treat seizures?

Also causes osteomalacia (softening of the bones)

A

Hydantoins e.g., Phenytoin

33
Q

Prodromal phase

A

Sensation before the actual seizure

Headache, confusion, anxiety, anger and tremors

34
Q

Aura

A

Warning of an on-coming seizure and beginning of the ictal phase.

bitter/acidic taste, deja vu, flickering vision, hallucinations, buzzing sounds

35
Q

Ictal phase

A

Beginning and the end of the seizure

Arm or leg stiffening, confusion, lip smacking, dyspnea, drooling, inability to speak or move.

36
Q

Post-ictal phase

A

Is the recovery period post-ictal phase.

Extremity weakness, body soreness, drowsiness, fear

37
Q

Parkinson’s Disease

A

Chronic degenerative disorder that primary affects the neurons of the basal ganglia resulting in tremors, rigidity, bradykinesia and postural changes.

38
Q

What foods can not be given to a patient taken Levodopa & Carbidopa?

A

High in protein