Neurological System Flashcards

1
Q

How many neurons are present in the human brain?

A

86 billion

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2
Q

Place the following species in descending order

1) Chimpanzee
2) Gorilla
3) Human
4) Elephant

A

4-3-2-1

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3
Q

What is the order of process of a nervous signal?

A

Reception -> treatment -> transmission

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4
Q

What is the structure of a cell membrane?

A

thin, elastic structure composed entirely of:

  • lipid barrier (bilayer)
  • Proteins
  • Carbohydrates
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5
Q

What is the lipid bilayer impermeable to?

A

It is impermeable to water and the usual water-soluble substances but permeable to lipid-soluble substances

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6
Q

What are the two types of membrane proteins?

A

Integral proteins & peripheral proteins

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7
Q

Describe an integral protein.

A

Protrudes through the membrane, acts as pores and channels, substance carriers

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8
Q

Describe peripheral proteins.

A

attached to only one surface of the membrane (often attached to the integral protein). Act as enzymes, controller of transport channels

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9
Q

What are the two basic processes of transport?

A

Diffusion and active transport

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10
Q

Describe simple diffusion.

A

it requires no energy, molecules move through interstices of lipid bilayer (lipid-soluble substances) and through protein channels for water and lipid-insoluble molecules

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11
Q

Protein channels are selectively permeable to one or more specific ions or molecules based on:

A
  • the diameter of the channel
  • the diameter of the substance
  • the shape of the channel
  • the nature of electrical charges along the surface of the channel
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12
Q

What are the two types of gates that regulate the opening and closing of protein channels?

A

Voltage-gated channels: gate responds to electrical potential, participates in the generation of AP
Chemical-gated (ligand-gated) channels: channel responds to the binding of another molecule with the channel, participates in the synaptic transmission (receptor)

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13
Q

Describe the process of facilitated diffusion

A

Molecule diffuses by using a specific carrier protein, it enters the pore and binds to the binding point of the protein. A conformational change occurs so that the pore opens to the opposite side. At this position, the molecule is released.

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14
Q

What is the role of facilitated diffusion?

A

Carrying large molecules like glucose and amino acids

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15
Q

True or False. (simple diffusion) Diffusion rate speed is proportional to the concentration of the transported substance (i.e. the higher the concentration, the faster the rate of diffusion)

A

True, it is false for facilitated diffusion where the diffusion rate approaches a max when the concentration of the substance increases

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16
Q

What are the factors that affect the net rate of diffusion?

A
  • Concentration difference (concentration gradient): from high concentration to low concentration
  • Electrical Potential Difference: electrical charges of ions causes them to move across the membrane even though there is no concentration gradient
17
Q

Define Active Transport

A

It requires energy. molecules or ions move across the membrane through a carrier protein against their concentration gradient and/or electrical gradient

18
Q

What are the two types of active transport according to the source of energy used?

A

Primary Active Transport (energy is directly driven from ATP) & Secondary Active Transport (2 different substances are transported, energy driven from concentration gradient of one of the transported substances)

19
Q

How many sodium and potassium ions are pumped in and out of the cell in the sodium-potassium pump?

A

3 Na+ pumped out

2 K+ pumped in

20
Q

What does the Sodium-potassium pump establish inside the cell?

A

it establishes a negative electrical potential

21
Q

What are the two substances transported in secondary active transport?

A

Principal & co-transported

22
Q

Where does the energy required to move the substances comes from?

A

It is from the concentration gradient of the principal transported substance (gradient energy)

23
Q

What are the two forms of secondary active transport according to the direction of diffusion of the two substances?

A

Symport (co-transport): the 2 substances move in the same direction
Antiport (countertransport): the 2 substances move in opposite direction

24
Q

What is the main goal of secondary active transport?

A

To maintain homeostasis in cell

25
Q

Example of Symport (glucose and sodium)

A

Na+ is the principal substance, glucose is the co-transported. Both substances move together into the cell

26
Q

Example of Antiport ( Sodium & Calcium or hydrogen)

A

the principal and co-transported are located on opposite sides of the membrane.
The principal moves from outside to inside while the co-transported goes from the inside to the outside

27
Q

True or False. Molecules are constantly kept with unequal concentrations inside and outside of the cell.

A

True