Neurological Disorders - CNS: Brain Flashcards
1
Q
Parkinson’s Disease - Pathophysiology
A
- Loss of dopamine stores
- Results in more excitatory neurotransmitters
- Imbalance affects voluntary movement
- Males greater than women
- 15% early onset genetic mutation
2
Q
Parkinson’s Disease - CMs
A
-
4 Cardinal Signs
> tremor
> rigidity
> bradykinesia/akinesia
> postural instability - Types:
> tremor dominate
> non-tremor dominate; a kinetic-rigid & postural instability
3
Q
Parkinson’s Disease - Stage 1
A
-
Initial Stage
> unilateral limb involvement
> minimal weakness
> hand & arm trembling
4
Q
Parkinson’s Disease - Stage 2
A
-
Mild Stage
> bilateral limb involvement
> masklike face
> slow, shuffling gain
5
Q
Parkinson’s Disease - Stage 3
A
-
Moderate Disease
> postural instability; not able to walk very well
> incr gait disturbances
6
Q
Parkinson’s Disease - Stage 4
A
-
Severe Disability
> akinesia
> rigidity
7
Q
Parkinson’s Disease - Stage 5
A
-
Complete ADL Dependence
> in later stages, psychiatric components come into play
> psychosis
> hallucinations
8
Q
Parkinson’s Disease - Diagnostics
A
- Hx
- 4 cardinal signs (2 of 4)
- Diagnosis confirmed by a positive response to levodopa trial
- PET scan; rule out
- Single-photon emission CT; rule out
9
Q
Parkinson’s Disease - Medical Management
A
-
Pharmacotherapy
> Levodopa; most effective; converts to dopamine; relieves manis -
Surgical Treatment
> deep brain stimulation (DBS)
> electrode implanted/blocks anticholinergic release
10
Q
Parkinson’s Disease - Nursing Diagnosis
A
- Impaired physical mobility
- Self-care deficits
- Constipation; due to lack of mobility
- Impaired nutrition
- Risk for injury
- Impaired verbal communication
- Knowledge deficit; family & pt
11
Q
Parkinson’s Disease - Nursing Interventions
A
- Improve mobility (w/in safety)
- Enhancing self care activities
- Improved bowel elimination; mobility & stool softeners
- Improved nutrition; aspiration risk
- Enhanced swallowing
- Assistive devices
- Family/pt education; PT/OT/Speech
12
Q
Dementia - Pathophysiology
A
-
Cognitive, functional, & behavioral changes eventually destroy a person’s ability to function
> subtle in onset; progress slowly - Not a normal part of aging
- Non-Alzheimer dementias
> vascular dementia
13
Q
Alzheimer’s
A
- Specific neuropathologic & biochemical changes tht interfere w/ neurotransmission
- Most common dementia
- Early onset (familial 40-65yrs)
- Late onset (>65yrs)
- Risk factors:
> age
> gender
> genetics
14
Q
Dementia (Alzheimer’s) - CMs
stage 1
A
- Early (mild), Stage I
-
first symptoms up to 4yrs
> independent in ADLs
> denies presence of symptoms
> forgets names; misplaces household items
> has short-term memory loss & difficulty recalling new info
> shows subtle changes in personality & behavior
> loses initiative & is less engaged in social relationships
> has mild impaired cognition & problems w/ judgement
> Demonstrates dcrd performance; especially when stressed
> unable to travel alone to new destinations
> often has dcrd sense of smell
15
Q
Dementia (Alzheimer’s) - CMs
stage 2
A
- Middle (moderate), Stage II
-
2-3yrs
> has impairment of all cognitive funcs
> demonstrates problems w/ handling or unable to handle money & finances
> is disoriented to time, place, & event
> is possibly depressed and/or agitated
> is incringly dependent in ADLs
> has speech & language deficits; less talkative, dcrd use of vocab, incringly nonfluent, & eventually aphasic
> incontinent
> psychotic behaviors; delusions, hallucinations, paranoia
> has episodes of wandering; trouble sleeping
16
Q
Dementia (Alzheimer’s) - CMs
stage 3
A
- Late (severe)
-
Stage III
> completely incapacitated; bedridden
> totally dependent in ADLs
> has loss of mobility & verbal skills
> possibly has seizures & tremors
> has agnosia
17
Q
Dementia (Alzheimer’s) - CMs
extra info
A
- Pts can show manis from any stage
- Pts can have issues from any stages at anytime
> mix & match
> slide btwn stages