Neurological Disorder Medical Management Flashcards
what are the neurological diseases dentists should be aware of?
Stroke (Cerebrovascular accident)
Parkinson’s Disease
Dementia and Alzheimer’s
Epilepsy
Multiple Sclerosis
Cerebrospinal Fluid Shunts
what are the risk factors for a stroke that dentists should be aware of?
◦ Hypertension
◦ Congestive heart failure
◦ Diabetes mellitus
◦ TIA or previous CVA
◦ Increasing age >75 years
◦ Elevated blood cholesterol or lipid levels
◦ Coronary atherosclerosis/Atrial fibrillation
◦ Cigarette smoking
what should be asked if a patient has a history of strokes?
- Date of the Stroke Event
- Type of Stroke
- Current Status
- Current Medical Therapy
- Residual Disabilities
- MD Consultation: if dental treatment is needed within 90 days
- Routine Dental Care Timing: should be delayed to 90 days after stroke
What analgesic is recommended for pain control in stroke patients, and which should be avoided?
- Acetaminophen is recommended because it does not increase bleeding risk
- ASA (aspirin) and NSAIDs due to increased bleeding risk
What is the recommended anesthetic dose and formulation for stroke patients?
a maximum of 2 cartridges of 2% lidocaine with epinephrine concentrations of 1:100,000 or 1:200,000
*reduce epinephrine use
what antibiotics should be avoided in stroke patients?
metronidazole and tetracyclines in patients taking Warfarin (decreases warfarin metabolism)
What is the purpose of INR in patients taking warfarin?
INR (International Normalized Ratio) measures blood clotting ability and is used to monitor anticoagulant levels in patients taking warfarin
At what INR value is it generally safe to proceed with routine dental treatment without modifying warfarin dosage?
If the INR is ≤ 3.5, routine dental care or simple oral surgery can usually proceed without modifying the warfarin dose
Is INR useful for monitoring antiplatelet drugs like aspirin or clopidogrel?
No, INR is not useful for monitoring antiplatelet drugs or NOACs
What local measures can be taken to minimize hemorrhage during dental procedures?
Use good surgical technique, suture, apply prolonged pressure, and use hemostatic agents like Gelfoam + thrombin, stents, or electrocautery
Why must bleeding risk be assessed in patients on antiplatelet or anticoagulant therapy before dental treatment?
Because these medications impair blood clotting and can increase the risk of prolonged bleeding during or after procedures
What are some common antiplatelet drugs that may increase bleeding risk?
Aspirin (ASA)
Plavix (clopidogrel)
Aggrenox (aspirin + dipyridamole)
discontinued Ticlopidine (Ticlid)
What are New Oral Anticoagulants (NOACs) and examples of them?
Apixaban (Eliquis)
Rivaroxaban (Xarelto)
Edoxaban (Savaysa)
Dabigatran (Pradaxa)
are there any issues with devices for stroke patients?
no
What drug-related precautions should be taken during dental treatment for stroke patients?
- Minimize the amount of anesthetic with vasoconstrictor—use no more than 2 cartridges of 2% lidocaine with 1:100,000 or 1:200,000 epinephrine.
- Avoid epinephrine in retraction cords to reduce cardiovascular risk.
- Avoid prescribing metronidazole or tetracyclines
What are emergency dental care guidelines for patients at risk of stroke or cardiovascular events?
- Keep appointments short and low-stress.
- Use nitrous oxide/oxygen sedation (N₂O/O₂) if needed.
- Monitor blood pressure and oxygen saturation.
- Recognize stroke symptoms (e.g., facial droop, speech issues).
- Provide oxygen and call EMS immediately if stroke is suspected.
what is the acronym for quick stroke diagnosis?
FAST
face
arm
speech
time
What are the key features of a generalized tonic-clonic (grand mal) seizure?
- Starts with aura in 1/3 of patients (unusual sensory perception).
- Tonic phase: muscle stiffness, pupil dilation, loss of consciousness.
- Clonic phase: jerking of limbs/head, possible incontinence.
- Seizure lasts ~60 seconds.
- Followed by confusion, drowsiness, and need for rest to regain function.
what should be asked if a patient has a history of seizures?
◦ Type of seizures
◦ Age at time of onset
◦ Cause of seizures
◦ Medications
◦ Regularity of MD visits
◦ Degree of control
◦ Frequency of seizures, date of last seizure
◦ Precipitating factors
◦ Prodromal symptoms – can you alert us if they occur?
◦ History of seizure related injuries
How should dental care be managed in epileptic patients?
- Well-controlled patients can receive normal dental care.
- Poorly controlled patients require MD consultation, may need additional meds, and sometimes referral for care under general anesthesia.
What is the concern with using antiepileptic drugs during pregnancy, and which are safer options?
- main concern is teratogenicity
- valproic acid and phenytoin pose higher risks (Category D)
- levetiracetam (Keppra) and lamotrigine (Lamictal) are considered safer (Category C)
What are the major dental and medical concerns associated with Dilantin (Phenytoin)?
- Causes gingival hyperplasia—manage with good oral hygiene and possibly surgery.
- Leads to bone marrow suppression—increased infection risk, delayed healing, and bleeding.
- May cause osteoporosis and serious conditions like Stevens-Johnson syndrome
- Classified as Pregnancy Category D due to teratogenic effects.
What are the major concerns and precautions for patients on Tegretol (carbamazepine)?
- Causes xerostomia, ataxia, and bone marrow suppression (increased infection risk, delayed healing, bleeding).
- Avoid ASA/NSAIDs due to bleeding risk.
- Avoid erythromycin, which can increase carbamazepine to toxic levels.
- Watch for osteoporosis and Stevens-Johnson Syndrome.
What are the key dental and systemic considerations for a patient taking Depakene (valproic acid)?
- Bleeding risks; petechiae, bone marrow suppression, decreased platelet aggregation
- Avoid ASA and NSAIDs
- Drowsiness
- Pregnancy concerns (D for seizures, X for migraines)