Neurological disease in exotics Flashcards

1
Q

What is the general approach to diagnosing health issues in small mammals?

A

• Detailed history (including husbandry)
• Detailed clinical exam
• Create a prioritised list of differentials
• Discussion with owner
• Diagnostic tests
• Treatment plan

This approach ensures a comprehensive evaluation of the animal’s health.

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2
Q

List some clinical signs observed in small mammals.

A

• Head tilt
• Weakness
• Paresis
• Swaying
• Tremor
• Seizures
• Circling
• Exophthalmos
• Ocular discharge
• Mydriasis
• Nystagmus
• Urinary incontinence
• Loss of anal tone
• Faecal impaction

These signs can indicate various health issues in small mammals.

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3
Q

What are the clinical signs of vestibular disease in small mammals?

A

• Nystagmus (vertical or horizontal)
• No Horner’s or facial nerve paralysis
• Can show other CNS signs

Central vestibular disease is characterized by these signs.

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4
Q

What are the differential diagnoses for small mammals presenting with neurological signs?

A

• Viruses
• Fungal
• Bacterial
• Parasitic
• Degenerative
• Trauma
• Husbandry issues
• Toxicity
• Metabolic
• Other (e.g. neoplasia, hypoxia)

A range of conditions can lead to similar clinical presentations in small mammals.

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5
Q

True or False: Otitis media is more common in lop rabbits.

A

True

Lop rabbits are predisposed to otitis media due to ear anatomy.

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6
Q

What is Encephalitozoon Cuniculi?

A

A fungus spread in rabbit urine, with over 50% of healthy rabbits being carriers.

Clinical signs include CNS damage and kidney damage, often leading to severe health issues.

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7
Q

Fill in the blank: The clinical signs of E. cuniculi include _______.

A

• Hind limb paralysis/weakness
• Torticollis
• Urinary incontinence
• Tremors

These signs indicate CNS damage caused by the pathogen.

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8
Q

What are the clinical signs associated with rabbit Fipronil toxicity?

A

• Seizures
• Tremors
• Hyperactivity
• Diarrhea
• Hypersalivation
• Hypothermia
• Death 11-14 days post-exposure

Fipronil affects the CNS by blocking GABA receptors.

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9
Q

What are some differential diagnoses for reptiles presenting with neurological signs?

A

• Viruses
• Fungal
• Bacterial
• Parasitic
• Degenerative
• Trauma
• Husbandry issues
• Toxicity
• Metabolic
• Other (e.g. egg binding)

Similar to small mammals, reptiles can have a variety of underlying causes for neurological symptoms.

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10
Q

What are the neurological signs of Inclusion Body Disease (IBD) in snakes?

A

• Head tremor
• Uneven pupils
• Muscle spasms
• Lethargy
• Reduced mental activity
• Poor righting reflex
• Reduced muscle tone
• Constipation

IBD can severely affect the neurological function of affected reptiles.

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11
Q

What is Marek’s disease and its clinical signs?

A

A viral disease in chickens characterized by:
• Lameness/leg paralysis
• Wing paralysis
• Weight loss/wasting
• Eye changes
• Tumours

Marek’s disease is caused by a herpes virus and can lead to significant health issues in poultry.

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12
Q

What is a common diagnostic test for heavy metal toxicity in birds?

A

• History and clinical signs
• Blood work
• Radiographs to identify metal in the GIT

A thorough diagnostic approach is essential to confirm heavy metal toxicity.

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13
Q

Fill in the blank: The treatment for E. cuniculi eases symptoms by reducing inflammation, but does not _______.

A

reverse damage already done

Supportive care is crucial, but recovery may be limited.

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14
Q

What are some general treatment principles for treating animal illnesses?

A

• Supportive care
• Remove toxins
• Pain relief
• Kill/treat the pathogen/infection
• Euthanasia if necessary
• Prevention is better than cure

Effective treatment often requires a multifaceted approach.

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15
Q

What are the clinical signs of heavy metal toxicity in birds?

A

• Regurgitation
• Lethargy
• Weakness
• Anorexia
• Weight loss
• Anaemia
• Polydipsia
• Diarrhea
• CNS signs: depression, seizures, head tilt, blindness

Heavy metal toxicity can have serious implications for both the GIT and CNS.

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16
Q

What diagnostic options are available for pathogen testing?

A

• Antibody testing
• Antigen testing
• PCR, ELISA
• Bacteriology
• Histology
• Samples (blood, urine, swabs, FNA/aspirate, biopsies)

These tests help identify specific pathogens causing illness.

17
Q

What is the primary method for preventing the spread of parasites in new rabbits?

A

Quarantine new rabbits and treat with fenbendazole.

Fenbendazole is an anthelmintic used to treat parasitic infections.

18
Q

How should diet changes be made to prevent hepatic lipidosis in rabbits?

A

Diet changes should be made slowly over 6 months.

Sudden changes in diet can lead to starvation and fat release from the liver.

19
Q

What are some liver supplements that can be used for hepatic lipidosis?

A

Milk thistle, Hepatosyl, lactulose.

These supplements may support liver function.

20
Q

What is the supportive treatment for heavy metal toxicity in rabbits?

A

Fluids, warmth, crop feeds.

Supportive care is crucial for recovery.

21
Q

What is the commonly used chelating drug for heavy metal toxicity?

A

Calcium EDTA.

It is administered BID until asymptomatic and then twice weekly.

22
Q

What is the expected passage time for small metal particles in the gastrointestinal tract?

A

4-5 days.

Larger pieces may require endoscopic or surgical removal.

23
Q

What is the treatment for Psittacosis in rabbits?

A

Doxycycline for 45 days.

Psittacosis is a bacterial infection that requires antibiotic treatment.

24
Q

What is the recommended approach for viral infections in rabbits?

A

Supportive care and prevention of spread.

There are no specific treatments for viral infections.

25
Q

What are the key components of good husbandry for rabbits?

A

Correct environment and diet, avoid access to toxins, good biosecurity.

Good husbandry practices help prevent disease.

26
Q

What does good biosecurity entail for rabbit care?

A

Good hygiene, keep ‘closed’ collections, quarantine and test new animals, prevent wildlife contact.

These measures help control disease spread.