Neurolocalization Flashcards

1
Q

What do the various parts of this diagram indicate?

A
  1. Intracranial
  2. C1-C5
  3. C6-T2
  4. T3-L3
  5. L4-S3
  6. PNS/LMN
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2
Q

What are the various parts involved in intracranial lesions?

A
  • Forebrain
    • cerebrum & diencephalon
  • Cerebellum
  • Brainstem
    • midbrain (mesencephalon)
    • pons (ventral metencephalon)
    • medulla (myelencephalon)
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3
Q

What are the various lobes of the forebrain associated with?

A
  • Frontal - motor
  • Temporal - auditory/vestibular
  • occipital - visual
  • parietal - somatosensory (proprioception)
  • pyriform - olfactory
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4
Q

Intracranial lesions localized to the cerebrum would result in what deficits?

A
  • seizures
  • behavior and/or mentation changes
  • circling
  • head pressing
  • menace deficits - contralateral side
  • blind with normal PLRs
  • hemi-neglect
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5
Q

Intracranial lesions localized to the diencephalon would result in what deficits?

A
  • signs similar to cerebral lesions
  • circle - either side (towards lesion)
  • endocrine dysfunction
    • PU/PD
    • abnormal eating/thermregulation
    • thalamic pain syndrome
  • decr to absent menace & vision
    • involvement of optic n. or lateral geniculate nucleus
  • stupor/coma due to Asc. Reticular Activating Syst.
    • midbrain to medulla
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6
Q

When you have a brainstem lesion in the midbrain, what are the deficits you see? What CN originate here?

A
  • CN III and IV
  • Disturbances in consciousness (ARAS)
  • UMN paresis to plegia (uni or bilateral)
  • Lesion of caudal midbrain/cranial pons = ipsilateral deficits (due to decussation)
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7
Q

When there’s a lesion in the pons, what types of deficits will you see? What CN originates here?

A
  • CN V originates
  • Change in consciousness
  • UMN paresis to plegia
  • Abnormal resp activity - major resp centers (Pons < medulla)
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8
Q

If your patient has a lesion in the medulla oblongata, what type of deficits might you see? What CNs originate here?

A
  • CN VI, VII, VII, IX, X, XI, XII
  • Alterations in consciousness
  • Rostral lesion = central vestibular
  • Caudal lesion = dysphonia, dysphasia, tongue paresis
  • Abnormal resp activity - major resp centers (pons < medulla)
  • Autonomic dysfunction - HR and BP
  • UMN paresis to plegia - ipsilateral
  • UMN for resp mm vs. LMN in phrenic n. (C5-C7)
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9
Q

If your patient has a lesion in the cerebellum, what type of deficits might you see?

A
  • Coordinates and regulates movement - does NOT initiate
  • Hypermetria -exaggerated movements
  • Ataxia WITHOUT paresis
  • Intention tremors
  • Vestibular signs - head tilt, nystagmus, circling
  • Decr menace with normal vision
  • Anisocoria - normal pupil usually dilated with slow PLRs
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10
Q

If you have a lesion at high cervical or high thoracic (C1-C5;T3-L3), limbs immediately behind it are going to have _______

A

Intact UMN reflexes

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11
Q

If you have a lesion at low cervical or low thoracic (C6-T2; L4-S3), the limbs immediately after it will _________

A

Have LMN reflexes (decreased or absent)

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12
Q

What would you expect to see with a patient who has a C1-C5 myelopathy?

A
  • Hemiparesis to hemiplegia vs. tetraparesis to tetraplegia
  • +/- pain
  • CP deficits x 4
  • +/- low head carriage; decr ROM
  • All 4 limbs affected
  • UMN reflexes x 4 Ataxia
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13
Q

What would you expect to see with a patient who has a C6-T2 myelopathy?

A
  • +/- pain
  • CP deficits x 4
  • +/- low head carriage; decr ROM
  • All 4 limbs affected
  • LMN reflexes to FLs
  • UMN reflexes to the HLs
  • +/- Horner’s - symp fibers in T1-T3
  • Don’t forget phrenic n. (C5-C7)
  • Ataxia and paresis - may look worse in HLs
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14
Q

What would you expect to see with a patient who has a T3-L3 myelopathy?

A
  • Normal FLs
  • CP deficits HL
  • +/- pain
  • Kyphosis
  • Paresis to plegia
  • UMN reflexes to HLs
  • UMN bladder (sphincters still intact, may be hyperactive)
  • Ataxia & paresis (para or mono)
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15
Q

What would you expect to see with a patient who has a L4-S3 myelopathy?

A
  • Normal FLs
  • CP deficits HL
  • LMN reflexes to HL
  • LMN bladder
  • +/- pain
  • Low tail carriage
  • Ataxia (para or mono)
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16
Q

What would you expect to see with a patient who has a PNS neuropathy?

A

Nerve = neuropathy

  • No ataxia
  • Decr to absent reflexes - patellar = ONLY reliable reflex
  • Decr to absent muscle tone
  • Varied distribution - poly vs. mononeuropathy
  • Neurogenic atrophy (very quick onset)
  • Variable CP deficits
17
Q

What would you expect to see with a patient who has a PNS myopathy?

A

Muscle = myopathy

  • Normal reflexes
  • +/- decr withdrawals
  • Normal CPs
  • Generalized weakness - exercise intolerance
  • Usually bilaterally symmetrical
  • +/- myalgia
18
Q

What would you expect to see with a patient who has a PNS junctionopathy?

A

NMJ = junctionopathy

  • Generalized weakness - interference of nerve-muscle communication
  • Varied reflexes - normal to absent
  • Usually diffuse distribution
  • +/- exercise intolerance