Neurodevelopment Disorders Flashcards

1
Q

dx in individuals under 5 who fail to meet expected developmental milestones in several areas of functioning

A

Global Developmental Delay

at least 2 SD below the mean

may not be ID when they are older

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2
Q

significant limits in intellectual functioning AND everyday adaptive functioning

onset before 18

A

Intellectual Disability

2 SD below mean (less than 70)

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3
Q

3 areas of adaptive functioning

A

conceptual (academic) skills
social skills
practical skills

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4
Q

t/f ID (mild ID in particular) more prevalent in developing countries or areas with lower SES

A

true

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5
Q

3 possible ID causes

A

perinatal insult
postnatal insult
prenatal

(in addition to chromosome)

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6
Q

__ is most common heritable etiology of ID

A

Fragile X

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7
Q

4 main early signs of ID

A
  1. delayed receptive / expressive language development
  2. adaptive delay
  3. . sings of cognitive delay/difficulty
  4. lack of appropriate play skills
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8
Q

what counts as lack of appropriate play skills?

A

playing with toys for younger children

functional play at an age where imaginative play would be expected

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9
Q

3 main interventions for ID

A
  1. systematic instruction within the school system
  2. peer tutors
  3. use of technology
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10
Q

a disability characterized by pervasive deficits in social communication functioning in addition to restricted and repetitive behavior patterns

A

ASD

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11
Q

prevalence of ASD

A

1 in 68 kids

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12
Q

t/f higher prevalence of asd in males

A

true

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13
Q

PDD

A

pervasive developmental disorders

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14
Q

HFA

A

high functioning autisim

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15
Q

AS

A

Asperger syndrome

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16
Q

PDD-NOS

A

pervasive developmental disorder not otherwise specified

17
Q

prevalence of ID

A

1/91

18
Q

t/f nearly half of individuals with ASD have ID average or above ID

A

true

19
Q

common co problem with ASD

A

depression and anxiety

20
Q

ASD full diagnostic evaluation

A
  1. comprehensive dev interview
  2. cognitive assessment
  3. adaptive assment
  4. structured dx testing
21
Q

t/f ASD can be diagnosed reliably as young as ___months

A

18 months

yet no longer tell a family that autism dx must wait until a child is 3 or older

22
Q

3 subtyps of ADHD

A
  1. inattentive type ADHD-1
  2. hyperactive impulsive type ADHD 2
  3. combined type ADHD C
23
Q

ADHD brings what 2 increased risk

A

TBI

Suicide attempt by early adulthood

24
Q

ADHD brings what 2 increased risk

A

TBI

Suicide attempt by early adulthood

25
Q

3 environment adhd risk

A
  1. VLBW
  2. lead exposureo
  3. teratogenic substance in uteru
26
Q

trisomy 21

A

downs syndrome

27
Q

most common genetic disorder with ID
usually mild-mod range

not typically inherited

A

downs

1/800 kids

28
Q

brushfield spot on iris

A

down syndrome

29
Q

50% of downs kids will have abnormalities__

A

cardiac

30
Q

FMR1 gene mutation X

inherited x linked dominant pattern

A

fragile X syndrome

31
Q

fragile X more severe in men or women?

A

men

32
Q

long narrow face, prominent jaw and forehead, large ears, very flexible fingers, flat feet, high arched palate, enlarged testes in males after pubery

A

fragile x

33
Q

co-occurring dz with fragil x

A

ASD
ADHD
anxiety
mood disorders

34
Q

FMR1 gene mutation

inherited x linked dom. ptn

A

prader willi syndrome

35
Q

most common inherited genetic disorder associated with ID

A

prader willi syndrome

36
Q

loss of UBE3A gene function

A

angelman syndrome

37
Q

tx asd with adhd

A

psychostimulant

38
Q

asd with anxiety/depression tx

A

SSRI

39
Q

asd with aggression / irritability

A

atypical antipsychotics