neurodegenerative disorders Flashcards
1
Q
Alzheimer’s disease
A
A-beta (beta amyloid) extracellularly
tau in neurons
2
Q
frontotemporal lobar degeneration
A
tau in neurons
3
Q
progressive supranuclear palsy
A
tau in neurons and glia
4
Q
corticobasal degeneration
A
tau in neurons and glia
5
Q
Parkinson disease
A
a-synuclein in neurons
6
Q
multiple system atrophy
A
a-synuclein in glia and some neurons
7
Q
amyotrophic lateral sclerosis
A
TDP-43 or SOD-1 (familial) in neurons
8
Q
Huntington disease
A
huntingtin in neurons
9
Q
spinocerebellar ataxias
A
ataxins (various) in neurons