neurodegenerative disorders Flashcards

1
Q

Alzheimer’s disease

A

A-beta (beta amyloid) extracellularly

tau in neurons

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2
Q

frontotemporal lobar degeneration

A

tau in neurons

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3
Q

progressive supranuclear palsy

A

tau in neurons and glia

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4
Q

corticobasal degeneration

A

tau in neurons and glia

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5
Q

Parkinson disease

A

a-synuclein in neurons

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6
Q

multiple system atrophy

A

a-synuclein in glia and some neurons

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7
Q

amyotrophic lateral sclerosis

A

TDP-43 or SOD-1 (familial) in neurons

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8
Q

Huntington disease

A

huntingtin in neurons

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9
Q

spinocerebellar ataxias

A

ataxins (various) in neurons

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