Neurodegenerative Diseases/SCI Flashcards
What is Huntington’s disease?
Slowly progressive, hereditary neurodegenerative disorder that causes cognitive,
psychiatric, and motor problems
Classified as:
*Genetic brain disorder
○ Progressive breakdown of brain cells
○ Deteriorates physical and mental abilities
○ No cure
○ Can affect personality, relationships, ability to work, manage household tasks,
finances
*Loss of ability to walk, speak, eat; full time care required
A 45-year-old patient diagnosed with Huntington’s disease is experiencing early cognitive, psychiatric, and motor impairments, which are beginning to impact their ability to manage household tasks and personal finances. Which of the following occupational therapy interventions would best address the patient’s current and future needs as the disease progresses?
A. Focus solely on memory exercises and cognitive retraining to maintain financial independence long-term
B. Prioritize progressive motor exercises to prevent further physical decline without considering cognitive or emotional needs
C. Implement a combination of task simplification for household management, adaptive equipment for mobility, and caregiver training, along with emotional support resources
D. Provide minimal intervention now and prepare for intensive physical therapy only when the patient reaches the advanced stages of the disease
Correct Answer:
C. Implement a combination of task simplification for household management, adaptive equipment for mobility, and caregiver training, along with emotional support resources.
What is Parkinson’s Disease?
- Loss of cells in the substantia nigra. The substantia nigra cells produce dopamine, a chemical messenger responsible for transmitting signals within the brain that allow for coordination of movement.
- Loss of dopamine causes neurons to fire without normal control, leaving patients less able to direct or control their movement
Which of the following are motor symptoms of Parkinson’s disease?
A) Bradykinesia
B) Anosmia
C) Freezing of Movement
D) Postural Instability
A, C, D
Parkinson’s Motor Symptoms
○ Bradykinesia
○ Rigidity
○ Tremor
○ Postural Instability
○ Gait complications
○ Freezing of Movement
A 68-year-old patient with Parkinson’s disease is experiencing bradykinesia, rigidity, tremor, postural instability, and episodes of freezing during gait, which interfere with daily activities and mobility. What would be the most effective combination of interventions to help the patient manage these motor symptoms and maintain functional independence?
A. Focus on strengthening exercises alone to reduce rigidity and improve muscle tone
B. Teach the patient compensatory strategies, such as the use of external cues (e.g., rhythmic counting or visual markers) to assist with gait and reduce freezing, along with exercises for balance and postural control
C. Advise the patient to perform all daily activities seated to avoid postural instability and prevent falls
D. Emphasize hand exercises exclusively to decrease tremor, without addressing gait or postural instability
B. Teach the patient compensatory strategies, such as the use of external cues (e.g., rhythmic counting or visual markers) to assist with gait and reduce freezing, along with exercises for balance and postural control.
A 65-year-old client with Parkinson’s disease demonstrates non-motor symptoms, including executive dysfunction, REM sleep behavior disorder, and sensory deficits such as anosmia. The client has reported difficulty with household management tasks and experiences frequent mood fluctuations that interfere with their daily routine and social interactions. Which of the following interventions would most effectively target the client’s non-motor symptoms, supporting both safety and functional engagement?
A. Introduce cognitive aids such as memory notebooks to improve executive function, create a sleep hygiene program to address REM sleep behavior disorder, and incorporate strategies to enhance olfactory cues for meal preparation.
B. Use cognitive-behavioral therapy (CBT) techniques independently to manage mood fluctuations and delegate all complex household tasks to a caregiver for improved safety.
C. Focus on physical exercises to enhance motor function, implement daily journaling for mood tracking, and recommend frequent breaks during tasks to improve focus and engagement.
D. Design a structured daily schedule with visual prompts to aid in task completion, introduce relaxation techniques to manage mood and improve sleep quality, and recommend compensatory safety strategies in the kitchen given the anosmia.
D. Design a structured daily schedule with visual prompts to aid in task completion, introduce relaxation techniques to manage mood and improve sleep quality, and recommend compensatory safety strategies in the kitchen given the anosmia.
Which of the following are non-motor symptoms for Parkinson?
A) Autonomic
B) Cognitive
C) Neuropsych
D) Sleep Dysfunction
E) Sensory Deficits
All of the above
Non-Motor Symptoms
○ Autonomic
○ Cognitive
■ Executive Dysfunction
■ Dementia ○ Neuropsych
■ Mood Disorders ○ Sleep Dysfunction
■ REM Behavioral Disorder ○ Sensory Deficits
■ Anosmia
A 52-year-old client diagnosed with Huntington’s disease is being evaluated using the Unified Huntington’s Disease Rating Scale (UHDRS). The occupational therapist uses this assessment to gather information across multiple domains impacted by the disease. Which of the following areas are included in the UHDRS to provide a comprehensive evaluation of the client’s symptoms?
A. Motor function, cognitive ability, behavioral symptoms, and functional capacity.
B. Motor function, sensory processing, social skills, and vocational skills.
C. Cognitive processing, sensory integration, visual-perceptual skills, and ADL performance.
D. Physical strength, vocational interests, emotional resilience, and memory recall.
Correct Answer:
A. Motor function, cognitive ability, behavioral symptoms, and functional capacity.
Explanation:
Huntington’s Disease Rating Scale (UHDRS)
○ Motor
■ Oculomotor function
■ Dysarthria
■ Chorea
■ Dystonia
■ Gait
■ Postural stability ○ Cognitive
■ Verbal Fluency
■ Symbol Digit Modalities
■ Stroop Interference Test
○ Behavioral
■ Depressed mood
■ Apathy
■ Suicidal thoughts
■ Anxiety
■ Delusions
■ Hallucinations
○ Functional
■ Independence scale
■ Functional capacity
■ Functional assessment
Which of the following treatment approaches is commonly used to manage symptoms and improve quality of life for individuals with Huntington’s and Parkinson’s disease?
A) Medications to manage movement and psychiatric symptoms.
B) Physical therapy (PT), occupational therapy (OT), exercise, speech therapy, and swallowing therapy to improve mobility, communication, and nutrition.
C) Social support interventions to help individuals cope with change, manage crises, and address difficult behaviors.
D) All of the above.
Correct Answer:
D) All of the above.
Explanation:
A comprehensive approach for managing Huntington’s and Parkinson’s disease includes medications to address both movement and psychiatric symptoms, rehabilitation therapies like PT, OT, exercise, speech therapy, and swallowing therapy to improve functional abilities, as well as social support to help patients and families cope with the emotional and behavioral challenges of these diseases.
For a client with Parkinson’s disease experiencing postural instability, tremors, and cognitive decline, which combination of interventions would best address both the motor and cognitive symptoms?
A. Medications to control motor symptoms, social support for coping with cognitive changes, and physical therapy for balance.
B. Exercise to improve strength, cognitive training exercises, and nutritional counseling to support general health.
C. Medication for movement symptoms, occupational therapy to enhance daily functioning, and social support for managing behavioral challenges.
D. Speech therapy for communication, occupational therapy for daily tasks, and an individualized exercise program to support mobility.
Correct Answer:
C. Medication for movement symptoms, occupational therapy to enhance daily functioning, and social support for managing behavioral challenges.
A client with Parkinson’s disease (PD) is receiving gait training to improve mobility. Which of the following visual cues have been shown to improve gait speed, stride length, and/or stride frequency in individuals with PD?
A) Transverse lines that increase gait speed and stride length.
B) Participants’ footprints that increase gait speed and stride length.
C) Rhythmic flashing light that lowers stride frequency and increases stride length.
D) All of the above.
Correct Answer:
D) All of the above.
Explanation:
Use of Visual Cues in PD
○ Transverse lines –
■ Increased gait speed
■ Increased stride length
○ Participants’ footprints –
■ Increased gait speed
■ Increased stride length
○ Rhythmic flashing light –
■ Lowered stride frequency
Visual cues are effective in improving gait performance in individuals with Parkinson’s disease because they:
A) Improve kinesthetic feedback and increase reliance on automatic motor control by stimulating the basal ganglia.
B) Function primarily as “static cues” that only provide step length markers without influencing motor control.
C) Provide “static cues” that act as markers for step length and “dynamic cues” that enhance optic flow, bypassing the damaged basal ganglia circuitry.
D) Only reduce the need for goal-directed motor control while bypassing the basal ganglia circuitry.
C) Provide “static cues” that act as markers for step length and “dynamic cues” that enhance optic flow, bypassing the damaged basal ganglia circuitry.
Explanation:
Why Visual Cues Work -
○ Function as ”static cues” – markers of step length
○ Function as “dynamic cues” – optic flow
○ Decrease reliance on impaired kinesthetic feedback
○ Switch from automatic to goal-directed motor control
○ Bypass damaged basal ganglia circuitry
When developing an intervention plan for a client with Parkinson’s disease, which of the following treatment approaches is most likely to yield the greatest benefits for improving motor function and overall well-being?
A) Encouraging participation in regular physical activity focused solely on aerobic exercise.
B) Focusing exclusively on flexibility exercises to improve range of motion.
C) Recommending strength training exercises as the sole form of physical activity.
D) Incorporating complex, multimodal exercise routines with an interpersonal component to promote motor control, balance, and social interaction.
D) Incorporating complex, multimodal exercise routines with an interpersonal component to promote motor control, balance, and social interaction.
Treating Parkinson’s disease
○ Recommendations to engage in regular physical activity *complex, multimodal
forms of exercise with an interpersonal component may confer the broadest
benefits.
When developing an occupational therapy intervention plan for a client with Parkinson’s disease, which home modification strategy is most likely to improve safety, independence, and overall quality of life?
A) Installing grab bars and ensuring adequate lighting in key areas to improve safety during mobility and reduce fall risk.
B) Redesigning the home to include a more minimalist aesthetic, prioritizing visual appeal over functionality.
C) Focusing on high-tech smart home devices that require complex learning, disregarding the client’s cognitive abilities.
D) Making changes to the home environment to promote relaxation and stress reduction, without addressing mobility or physical safety concerns.
Correct Answer:
A) Installing grab bars and ensuring adequate lighting in key areas to improve safety during mobility and reduce fall risk.
When working with a client with Parkinson’s disease (PD), which of the following interventions would most effectively improve daily physical performance, participation in meaningful activities, and overall quality of life, while considering the impact of PD-related nonmotor symptoms (e.g., cognitive impairment, depression)?
A) Focus solely on medication management for movement symptoms, ignoring the impact of nonmotor dysfunction on daily activities.
B) Implement targeted external cues, such as visual or auditory prompts, to regulate movement during daily activities and provide social support through group therapy sessions with other individuals living with PD.
C) Design a physical exercise routine that includes only high-intensity aerobic activity, disregarding cognitive or emotional factors.
D) Recommend complete lifestyle changes, including dietary restrictions, without addressing mobility, cognitive, or social needs.
B) Implement targeted external cues, such as visual or auditory prompts, to regulate movement during daily activities and provide social support through group therapy sessions with other individuals living with PD.
Correct Answer:
B) Implement targeted external cues, such as visual or auditory prompts, to regulate movement during daily activities and provide social support through group therapy sessions with other individuals living with PD.
A 28-year-old patient is diagnosed with transverse myelitis, resulting in inflammation and damage to the spinal cord. Which of the following causes of spinal cord dysfunction is most associated with infections like transverse myelitis?
A) Neoplasm
B) Infections such as syphilis or transverse myelitis
C) Spinal cord abscess
D) ALS (Amyotrophic Lateral Sclerosis)
Correct Answer:
B) Infections such as syphilis or transverse myelitis
Rationale:
Transverse myelitis is an inflammatory condition of the spinal cord often linked to viral or bacterial infections. Syphilis can also cause spinal cord damage. Neoplasms and ALS are not typically caused by infections, while spinal cord abscesses are another form of infection that could lead to similar symptoms.
A patient presents with a mass located near the spinal cord that is exerting pressure on the cord, leading to weakness and sensory changes in the affected areas. This mass is identified as a tumor. Which of the following conditions is this most likely to be?
A) Spinal cord abscess
B) Thrombosis
C) Spondylitic OA
D) Neoplasm (Tumor)
D) Neoplasm (Tumor)
Rationale:
A neoplasm, or tumor, can put direct pressure on the spinal cord, leading to neurological symptoms such as weakness and sensory changes. Spinal cord abscesses can cause similar symptoms, but they are typically due to infection rather than a mass. Spondylitic OA involves degenerative changes in the spine, and thrombosis refers to a blood clot, neither of which are directly related to tumor growth.
A 35-year-old patient with a history of motor neuron disease is experiencing progressive muscle weakness, especially in the extremities. They are also reporting difficulty with speech and swallowing. Which of the following conditions is most likely related to their spinal cord dysfunction?
A) ALS (Amyotrophic Lateral Sclerosis)
B) Transverse Myelitis
C) Syphilis
D) Spondylitic OA
Correct Answer:
A) ALS (Amyotrophic Lateral Sclerosis)
Rationale:
ALS is a neurological disease that affects motor neurons, causing progressive weakness, loss of motor function, and symptoms like difficulty with speech and swallowing, which aligns with the patient’s presentation. Transverse myelitis and syphilis can also affect the spinal cord, but they typically present with different patterns of symptoms. Spondylitic OA affects the spine but is less likely to cause the same pattern of motor neuron dysfunction.
A 45-year-old patient is diagnosed with a spinal cord condition that is linked to the development of a blood clot which then cuts off the blood supply to the spinal cord. Which of the following terms describes the mechanism that leads to spinal cord ischemia in this patient?
A) Embolus
B) Spondylitic osteoarthritis
C) Thrombosis
D) Spinal cord abscess
Correct Answer:
C) Thrombosis
Rationale:
Thrombosis refers to the formation of a blood clot that obstructs the blood supply to the spinal cord, leading to ischemia and potential spinal cord damage. An embolus is a clot that becomes lodged in a vessel, whereas spondylitic OA involves degeneration of spinal structures, and a spinal cord abscess is an infection.
A 60-year-old patient with a history of chronic back pain presents with progressive weakness in the lower extremities, difficulty breathing, and reduced sensation below the waist. The physician suspects a neurological condition affecting the spinal cord. Given the following potential causes, which of the following conditions is most likely to contribute to the patient’s symptoms based on the presentation of weakness, sensory loss, and breathing difficulty?
A) Hemorrhage resulting in ischemia or pressure on the cord
B) Spinal cord abscess due to bacterial infection
C) Thrombosis, leading to the development of a blood clot cutting off blood supply to the cord
D) Spondylitic osteoarthritis (OA) of the spine causing mechanical compression
Correct Answer:
A) Hemorrhage resulting in ischemia or pressure on the cord
Rationale:
Hemorrhage can lead to spinal cord ischemia or pressure, causing neurological deficits such as weakness, sensory loss, and difficulty breathing, particularly if the hemorrhage is in the cervical or upper thoracic region. The other options (abscess, thrombosis, spondylitic OA) may contribute to similar symptoms but are less likely to cause the same acute, widespread neurological dysfunction in this context.