Neurobio introduction Flashcards

1
Q

neurons make up circuits that as a whole are a neural system what are the 3 neural systems and their functions?

A

sensory systems: brings in information such as the state of organisms and the environment

associational systems: higher orders function of cognition such as perception, memory, attention, emotion, language, and thinking.

Motor system: organize and generate movements and actions

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2
Q

Regulator sequences are made up of promoters and introns what is its functions.

A

they determine when and where and how readily a gene will be expressed.

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3
Q

scientists such as Camillo Golgi and Santiago Ramon and Charles Sherringtion studied the brain and came up with theories as to how neurons are connected. Name and describe both.

A

The reticular theory says that the nervous system is not made up of discrete cells but by a web of cells all connected through cytoplasmic links

The neuron doctrine says that the nervous system is made up of discrete cells that communicate at specific points of contact called synapses.

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4
Q

how do neurons work

A

they receive and transmit information through action potentials.

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5
Q

how do dendrites work

A

they receive information from other neurons by binding to chemical neurotransmitters from other neurons.

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6
Q

how do axons work

A

conducts electrical impulses away from a neuron in order to release a chemical neurotransmitter from its terminal.

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7
Q

what are the two types of neurons

A

local circuit neurons; (interneurons) that have short axons and communicate only with their nearest neighbors.

Projections neurons: have very long axons that communicate to a distant target

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8
Q

what is convergence

A

a neuron with lots of dendrites ad a lot of dendritic branching will receive more information from many different neurons

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9
Q

what is integration

A

all of the inputs are summed and contribute to a single output from the axon

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10
Q

what is divergence

A

although there is typically only 1 axon exiting a neuron cell body the axon can branch to connect to other neurons

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11
Q

synaptic vesicles

A

membrane-bound structures that contain chemical neurotransmitters and releases neurotransmitters at the synapse to communicate with post-synaptic cell.

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12
Q

synaptic cleft

A

extracellular space between pre- and post-synaptic surfaces

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13
Q

myelin sheath

A

insulated (lipid-rich) wrapping around axon

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14
Q

what two cells wrap around the axons

A

oligodendrocytes or Schwann cells

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15
Q

the soma contains all organelles what do dendrites contain and axons contain

A

dendrites contain ribosomes and axons contain mitochondria in the axon terminals

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16
Q

nodes of ranvier

A

patches of uninsulated axon

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17
Q

what courses through the axons and dendrites

A

microtubules

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18
Q

what does tau do

A

bundles the microtubules together

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19
Q

what is located at the tip of dendrites and why

A

actin and because they are actively growing and they can change shapes

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20
Q

what is the functions of dendrite spine on the dendrites

A

to increase surface area of the dendrite so that more synapses can form.

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21
Q

spiny neurons contain alot or little amounts of spines

A

alot

22
Q

does aspinous neurons contain none or alot, or a little spines

A

none

23
Q

what do spines of the neurons contain

A

actin

24
Q

what is neuromuscular junction

A

synapses between a motorneuron axon and a muscle cell

25
Q

what is dystrophin and its function

A

an intracellular scaffolding protein that links receptors to actin cytoskeleton and localizes them to synapses

26
Q

what does mutations in the dystrophin gene lead to

A

leads to muscular dystophy

27
Q

what do each of these stains do
golgi
fluorescence
nissl stain

A

golgi- impregnation with silver salts
fluorescence- injection, expression, or immune labeling with fluorescent markers
nissl stain- stain with cresyl violet which marks ribosomes and nucleolus

28
Q

where are astrocytes located and its function

A

found in the CNS
function is to maintain ionic and chemical environment of brain for optimal neuronal function
forms the blood brain barrier
forms new synapses
some retain stem cell characteristics

29
Q

where are oligodendrocytes located and its function

A

located in the CNS
function is to form the myelin sheath around the CNS axons by wrapping tightly around them
some retain stem cell characteristics
schwann cells have the same function in the PNS

30
Q

what is the function of microglia

A

act like brain macrophages
come from hematopoietic stem cells
they clean up debris by phagocytosis from sites of neuronal turnover or injury
when activated will move to site of injury and release cytokines that regulate inflammation

31
Q

stem cells function

A

cells that can divide
1 daughter cell remains a stem cell while the other daughter can differentiate into a more specialized cell type

32
Q

glial stem cells function

A

can give rise to neurons or glia and have greater potential

33
Q

why are oligodendrocyte stem cells sometimes called precursors

A

sometimes called precursors because the other daughter cells will almost become an oligodendrocytes

34
Q

afferent pathway

A

a pathway of neurons that carry sensory information toward the brain or spinal chord

35
Q

local pathway

A

a pathway of interneurons that convey information between different regions within the brain and spinal chord (receives information from the afferent

36
Q

efferent pathway

A

a pathway of neurons that carry motor information or effector information away from the brain or spinal chord to elicit a response

37
Q

gray matter function

A

regions within the CNS that have a high density of neuronal cell bodies

38
Q

nucleus

A

a collection of neuronal cell bodies that are located deep in the brain

39
Q

cortex

A

a sheet of neuronal cell bodies arranged in a layer

40
Q

white matter

A

regions within the CNS that contain mostly myelinated axons

41
Q

tracts

A

bundles of axons that connect distinct regions within the brain and or spinal chord

42
Q

commissures

A

bundles of axons that connect neurons on one side of the brain to the other side

43
Q

columns

A

bundles of axons within spinal cord that convey sensory Info to brain or motor info away from the brain

44
Q

ganglion

A

collection of neurons that reside in the peripheral nervous system

45
Q

nerve

A

a bundle of axons within the peripheral nervous system that travel between a ganglion and a particular target

46
Q

autonomic branch PNS

A

not under conscious control, control cardiac muscles, smooth muscles , glands

47
Q

somatic branch of PNS

A

under conscious control, controls skeletal muscles

48
Q

parasympathetic

A

controls rest and digest functions

49
Q

sympathetic

A

controls fight and flight functions

50
Q

enteric

A

controls gut motility and secretions