Neuroanatomy & Neuroplasticity Flashcards
produce, store and circulate CSF
ventricles
3 layers of the brain meninges
pia mater (innermost), arachnoid, dura mater (outermost)
hint: meninges PAD the brain
this layer of the meninges molds around sulci and gyri. what is?
pia mater (innermost, beneath sub-arachnoid space)
subdural space
beneath dura mater, above arachnoid layer
bleed = subdural hematoma
central point for all incoming and outgoing information and basic life functions of brain
Brain stem
3 components of brain stem
medulla, pons, midbrain
control center for involuntary reflexes such as breathing, HR, BP, swallowing, vomiting
medulla (lowermost part of brain stem)
essential for facial movements, facial sensation, hearing, eye movements
pons - connects cerebellum and cerebral cortex
part of brain stem involved in vision, hearing, alertness, and arousal
midbrain
these nuclei modulate arousal, alertness, concentration, biological rhythms
reticular activating system
which sense does NOT pass through diencephalon
smell
all others relay through thalamus
controls autonomic nervous system (temp, hunger, thirst, endocrine, sleep-wake, emotion, behavior)
hypothalamus (diencephalon)
injury to this brain region affects voluntary motor nerves, causing slowness and muscular rigidity
basal ganglia - regulates motor and premotor cortex
controls direction, rate, force, steadiness of movements
cerebellum
result of injury to basal ganglia vs cerebellum
basal ganglia - slowness, loss of movement, muscular rigidity
cerebellum - trouble with fine motor movement, trajectory, balance, proprioception
gyri vs sulci vs fissures
gyri - elevated ridges
sulci- small grooves
fissures - deep grooves
injury to this region of the cortex causes difficulty making decisions, organizing and prioritizing, initiating and inhibiting actions, controlling emotions
prefrontal cortex
a patient presents with reduced motivation, impaired attention, and poor judgement following a TBI. What area of their cortex is likely affected?
frontal lobe
match:
Broca’s area and Wernicke’s area
parietal and frontal lobe
Broca’s - frontal (L)
Wernicke’s - parietal (L)
a patient presents with agraphia, acalculia, and aphasia after a TBI. The area of the cortex most likely affected is ____
somatosensory cortex, parietal lobe
atlas and axis
first (atlas) and second (axis) vertebra (cervical)
atlas - up and down skull movement
axis - side to side skull movement
spinal cord passes through ____ into vertebral canal
foramen magnum
central cord syndrome
cervical injury site, incomplete injury
often result of fall in person with neck arthritis or spondylosis
presents as weak/numb arms and often accompanied by bowel/bladder incontinence
Brown-Sequard syndrome
only one side of spinal cord is injured
ipsilateral paralysis/ loss of touch sensation
contralateral loss of pain/temp
anterior cord syndrome
loss of muscle control, pain/ temp sensation below level of lesion
(retain proprioception/touch sensation)
posterior cord syndrome
presents with strength but no sense of where limbs are in space below level of damage (proprioception)
CT scan and use
computed tomography - combines multiple X-rays to produce cross-sectional and 3D view
use to identify gross anatomical changes
brain imaging appropriate for soft tissues
MRI (magnetic resonance imaging)
more detail than CT scan
diffusion tensor imaging and use
type of MRI, measures rate of water diffusion between cells
provides info about connectivity and continuity of neural pathways
open TBI are primarily (focal/diffuse)
focal (such as contusions, lesions, hematomas)
rotational/angular forces that cause traumatic inertial brain injuries are primarily (focal/diffuse)
diffuse (such as hemorrhage)
Hebbian learning
basically, neurons that fire together wire together (neuroplasticity)
T/F: as our behavior and experience changes, there are resulting changes to our brain topography
TRUE
the size and complexity of a ____ determine the volume of synapses
dendrite arbor (dendritic spines have ability to change in response to experience)
neurogenesis occurs in which specific regions of the developed brain?
hippocampus - subventricular zone and dentate gyrus
excitotoxicity
failure of neurons to maintain resting potential due to sodium-potassium pump failure and subsequent accumulation of sodium and calcium
(secondary injury to brain injury)