Neuroanatomy and neurophysiology - Done Flashcards

1
Q

Astrocytes:

A

maintenance of homeostasis, formation of scar tissue (gliosis), each synapse is surrounded by an astrocyte
- neurotansmitters cannot escape from a synaptic cleft.

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2
Q

Oligodendtrocytes / Schwann cells:

A

forms a myelin sheaths in the CNS / in the peripheral nervous system.

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3
Q

Microglial cells:

A

phagocytes which are activated by the inflammatory and degenerative processes affecting nervous system.

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4
Q

Ependymal cells:

A

form an ependyma = a lining of the ventricles and central canal.

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5
Q

Which type of fiber does not have a myelin sheath?

A

C type

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6
Q

Which type of fiber is the thickest?

A

alpha

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7
Q

What is in the forebrain?

A

Diencephalon

  • Thalamus
  • Hypothalamus
  • Subthalamus
  • Epithalamus

Telencephalon
* Cerebrum

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8
Q

What is in the midbrain?

A
  • Tectum

- Cerebral peduncule

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9
Q

What is in the hindbrain?

A
  • Medulla
  • Pons
  • Cerebellum
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10
Q

Upper neuron =

A

motor neuron deriving from the cerebral cortex and going down to the spinal cord / to the motor nuclei of cranial nerves

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11
Q

Lower neuron =

A

motor neuron located in the anterior nerve root/ in the motor nuclei of cranial nerves

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12
Q

Somatosensory receptors:

A
  • interoception
  • exteroception
  • proprioception
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13
Q

Exteroception:

A
  • chemoreceptors
  • teloreceptors
  • cutaneous receptors
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14
Q

Proprioception:

A
  • vibration

- sense of position of muscle to joints

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15
Q

Exteroception - chemoreceptors:

A
  • taste

- smell

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16
Q

Exteroception - teloreceptors:

A
  • vision

- hearing

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17
Q

Exteroception - cutaneous receptors:

A
  • nociceptors (pain)
  • mechanoreceptors (touch, pressure)
  • thermoreceptors (temperature)
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18
Q

Cranial nerve III innervates what muscle(s) of the eyes?

A
  • superior oblique m.
  • inferior oblique m.
  • medial rectus m.
  • superior rectus m.
  • levator palpebrae m.

LESION: Affected eye is down and out, ptosis, mydriasis.

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19
Q

Cranial nerve IV innervates what muscle(s) of the eyes?

A
  • Trochlear m.

LESION: Affected eye is up and to the nose

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20
Q

Cranial nerve VI innervates what muscle(s) of the eyes?

A
  • Lateral rectus m.

LESION: Affected eye is horizontally and to the nose

21
Q

Constriction of the pupil:

A
  • parasympathetic component

- Edinger-Westphal nucleus

22
Q

Dilation of the pupil:

A
  • sympathetic component

- thoracic sympathetic trunk

23
Q

Amygdala:

A
  • Emotions - aggression, fear, pleasure, a reward
  • Regulation of motivation
  • Sexual arousal
  • Primitive emotional memory

Cooperates with endocrine and autonomic systems!

24
Q

Hippocampus:

A
  • Short-term and long-term memory
  • Learning
  • Also takes part in affective response
25
Parahippocampal gyrus:
- Visuospatial memory - Episodic memory - Mediates the connection between contextual processing and emotion, facilitating emotion understanding and expectations of our environment
26
Thalamus:
a relay station to the cerebral cortex
27
Hypothalamus:
regulation of hunger, thirst, response to pain, levels of pleasure, sexual satisfaction, anger and aggressive behavior.
28
Cingulate gyrus:
cooperates with autonomic system
29
Fornix:
a linkage between hyppocampus and mammillary bodies
30
Mammilary bodies:
formation of the memory
31
Entorhinal cortex and piriform cortex:
receive smell input in the olfactory system
32
Nucleus accumbens:
pleasure, reward, addiction
33
Functions of basal ganglia and extrapyramidal tract:
- Initiation and facilitation of voluntary movements - Suppresion of unwanted or involuntary movements - Posture and muscle tone - Integration of sensory and motor impulses, proprioceptive feedback
34
Circle of Willis:
- anterior communicating artery - anterior cerebral artery - internal carotid artery - middle cerebral artery - posterior communicating artery - cerebral artery
35
What is the blood brain barrier (BBB) made from?
- Made from epithelial cells (tight junctions) and astrocytes. - Damaged by inflammatory process.
36
Regions without blood-brain barrier:
- Median eminence of hypothalamus - Posterior lobe of pituitary gland - Pineal gland - Area postrema
37
What is the blood brain barrier not permeable for?
Not permeable for bacteria, hydrophilic and lipophilic molecules (drugs!)
38
What is the blood brain barrier permeable for?
Permeable to gases, glucose, amino acids, hydro soluble and lipo-soluble molecules.
39
Coverings of the brain and spinal cord:
- dura mater - arachnoid - pia mater
40
Dura mater:
thick and resistant, made form two layers
41
Arachnoid:
thin, transparent, like a spider web
42
Pia mater:
thin, delicate, coats closely brain and spinal cord
43
Spaces of the skull and spine:
- epidural space: meningeal arteries - Subdural space: emissary veins - Subarachnoid space: circle of Willis
44
What secretes CSF?
Actively secreted by choroid plexuses (mainly in lateral ventricles) to subarachnoid space, 500 ml/day, 130 -150ml in the brain
45
Where is the CSF resorbed?
It is resorbed to the bloodstream by arachnoid granulations located mainly in the superior sagittal sinus
46
Characteristic of normal CSF:
- Clear and colourless - Up to 4 cells, mainly lymphocytes - Glucose 50-60% of blood glucose - Little protein
47
Spinal cord:
- 7 cervical vertebrae, 8 cervical nerves!! - Sympathetic part: (C8)Th1-L2 - Parasympathetic part: S1-S4 - Medullar cone-L1/L2 - Cauda equina
48
Spinal cord reflexes:
- afferent impulses: from receptors at the body surface or internal organs - efferent impulses: e.g. to skeletal muscles