Neuroanatomy Flashcards
Microglia
- immune cells of CNS
- impt for phagocytosis and inflammation
Schwann cells
provide myelination for PNS
Oligodendrocytes
provide myelination for CNS
Astrocytes
- types: fibrous (white matter), protoplasmic (gray matter), radial
- angiogenesis, synaptogenesis, maintenance of BBB
- metabolite exchange, ion maintenance
- has perivascular and perineural feet
Satellite cells
- function as astrocytes in ANS
- neural crest origin
Polydendrocytes
stem cells of brain
Ependymal cells
- line the central canal
- columnar to cuboidal epithelium
- free exchange of fluid
- basal side contacts astrocytes
Node of Ranvier
- where 2 Schwann cells meet
- where APs are regenerated in order to propagate
Initial Segment
- initial part of the axon before myelinated part
- where AP is INITIATED
Are synapses myelinated?
no
Internode
- between nodes of Ranvier
- lined by Schwann cells
Components of Schwann cells
- nucleus in outer cytoplasmic belt
- terminal cytoplasmic spiral
- transverse and longitudinal Scmidt Lanterman incisures
Myelination in CNS vs PNS
- CNS has oligos that form many internodes
- PNS has Schwann cells that only form 1 internode each
- oligos have longer processes
Components of BBB
endothelium and astrocytes
Major segments of brain
telencephalon diencephalon mesencephalon metencephalon rhombencephalon
Components of brainstem
midbrain
pons
medulla
cerebellum
Where does the spinal cord end?
T12-L1
Direction of transmission of spinal cord dorsal and ventral roots
dorsal root - afferent
ventral root - efferent
Important motor pathway to the periphery
corticospinal (pyramidal) tract
Pain and temperature from the periphery
spinothalamic tract
Position sense pathway
Dorsal (posterior) column - has pseudounipolar neurons
Where is the autonomic nervous system regulated?
Hypothalamus and thalamus
Sympathetic spinal segments
T1-L2
Parasympathetic spinal segments and location
S2-S4 and Brainstem CN III, VII, IX, X
What passes through optic canal?
Optic Nerve (CNII)
What passes through the superior orbital fissure?
CN III
CN IV
CN VI
CN V1
What hole in the skull does the spinal cord connect to the brainstem?
Posterior fossa