Neuroanatomy Flashcards
What is the central nervous system (CNS) composed of? What does the CNS contain?
Brain, spinal cord
Motor, sensory and relay neurons
What is the peripheral nervous system (PNS) composed of? (What types?)
cranial nerves (12), spinal nerves, peripheral nerves Motor and sensory neurons
What is the autonomic nervous system?
Is present in both the CNS and PNS
Is divided into sympathetic and parasympathetic
Innervates the viscera and smooth muscle
What 2 ways can the nervous system be classified to according to a) function b) location?
a) Somatic and autonomic N.S.
b) central and peripheral N.S. - CNS, PNS
What is somatic nervous system?
Is present in CNS and PNS
Is under our control to a degree
Innervates skeletal muscle
Detects changes in external environment and controls movement
Name 9 functions of the parasympathetic nerves in the autonomic N.S (ANS).
Constrict pupils Stimulates salvia Slows heartbeat Constricts airways Stimulates activity of stomach Inhibits release of glucose, stimulates gallbladder Stimulates activity of intestines Contracts bladder Promotes erection of genitals
Name 10 functions of the sympathetic nerves in the autonomic N.S (ANS).
Dilate pupils Inhibits salvia Increases heartbeat Relaxes airways Inhibits activity of stomach Stimulates release of glucose, inhibits gallbladder Inhibits activity of intestines Secretes epinephrine and norepinephrine Relaxes bladder Promotes ejaculation and vaginal contraction
What type of matter is on the superficial/outer layer of the brain?
Grey matter
What type of matter is more deep in the brain?
White matter
What is the internal capsule?
A longitudinal fissure that splits the brain in 2. There is one internal capsule in each hemisphere. It acts like a funnel.
What is the corona radiata?
Funnels neurons from the cortex
What is the corpus callosum?
Connects the right and left hemispheres of the brain via white matter (myelinated nerve fibres). This allows communication between the 2 hemispheres
What is the cerebrum?
The cerebrum is the higher brain centre. Its the largest part of the brain. Is made up of 2 hemispheres with 4 lobes in each Is contains the diencephalon and the basal ganglia
What is the brainstem?
Its responsible for vital functions (respiration, heart rate, sleep-wake cycles). It contains midbrain, pons, medulla oblongata
What are the main structures of the brain?
Name the 4 lobes of the cerebrum
Cerebrum, Cerebellum, Brainstem
Frontal, parietal, temporal, occipital
What is the difference between sulci and gyri of the brain?
Sulci: the indentations between each gyri. (troughs) e.g. central sulcus
Gyri: are the elevated part of the brain - form the ridges (peaks)
What is the function of the frontal lobe?
Speech production, intelligence, emotion, personality, movement planning
What is the function of the parietal lobe?
Interpreting sensation -identifies the body region being stimulated (this is called spatial discrimation)
Contains the primary somatosensory cortex and the somatosensory association cortex
What is the function of the occipital lobe?
Vision
Contains the primary visual cortex and the visual association cortex
What is the function of the temporal lobe?
Hearing
Contains the primary auditory cortex
Contains Wernicke’s area which is responsible for understanding and remembering what is heard
What are fissures in the brain?
They are deeper sulcus and separate larger regions of the brain e.g. horizontal /transverse fissure, longitudinal fissure separates left and right sides of the brain
What is the function of the primary motor cortex?
Controls movement
Is responsible for precise/skilled voluntary skeletal muscle movement
What is the function of the pre-motor cortex?
Motor planning
What is the function of Broca’s area?
Involved in speech production
What is the difference between damage to Wernecke’s area and Broca’s area?
Broca’s area - they know what to say but they cannot say it. May have disorder syntax (speech), get stuck on a word
Wernecke’s area: the sentences do no make sense as the patient is oblivious to this
Where is the motor homunculus located?
Pre-central gyrus of the motor cortex
Where is the sensory homunculus located?
Post-central gyrus in the somatosensory cortex
What is the motor homunculus?
The amount of grey matter given to each body part in the homunculus is governed by the functional requirement of that body part e.g. hands are larger due to their need for fine movements
What is the sensory homunculus?
The amount of grey matter given to each body part in the homunculus is governed by the sensory requirement of that body part e.g. hands are larger due to their need for a larger amount of sensory input
What is the function of the pre-frontal cortex?
Takes 25 years to mature
Involved in higher decision-making
What structures are contained within the limbic system?
Amygdala, hippocampus, cingulate gyrus/cortex, lots of debate
What is the function of the limbic system?
Processes + regulates emotions, recognises danger
Highly connected to the endocrine and autonomic nervous system
What is the function of the hippocampus?
Consolidates long-term memories
What is the function of the amygdala?
Processes smell, emotions and fear. Re-plays memories
What is the function of the cingulate gyrus/cortex?
Regulates emotions. Directs behaviour to avoid painful situations
What is the function of the basal ganglia?
Receives sensory and motor information from the cortex and the brainstem
Controls movement, posture and muscle tone
What brain structures make up the diencephalon and what are the functions of each?
Thalamus - receives information from all over the brain and spinal cord and brings it to the cerebral cortex
Hypothalamus (regulates 4F’s -feeding, fighting, fleeing, fornication)
Epithalamus (secretes melatonin)
What is the function of the cerebellum and where is it located?
Located between brainstem and cerebrum
Is dedicated to fine motor movement, balance, smooth and co-ordinated movements, motor learning
What part of the brainstem is continuous with the spinal cord?
Medulla
What connects the 3 areas of the brainstem?
The reticular formation
What is the function of the pons?
Breathing, dreaming, links cerebellum to brainstem
What is the function of the medulla oblongata?
Cardiovascular centres (blood pressure)
What is the function of the midbrain?
Contain centres for eye movement, blood pressure, processes visual and auditory information, the generation of reflexes
From what sugar does the brain take its nutrients?
Glucose
How does the brain get oxygen and why?
The brain cannot make oxygen or store it. It gets oxygen from the blood brain barrier.
What 3 arteries diverge from the Circle of Willi?
Anterior cerebral artery (ACA)
Middle cerebral artery (MCA)
Posterior cerebral artery (PCA)
What areas of the brain does the MCA supply?
Lateral aspects of the brain
Where does the PCA go to?
Occiput
What artery branches out from the PCA?
Basilar artery
What are the levels of protection for the brain?
skull, meninges, cerebral spinal fluid (CSF), blood brain barrier (BBB)
What is the function of CSF?
provides nutrition, removes waste from the brain. Protection, provides buoyancy to the brain
What are the functions of the skull in protecting the brain?
Protects the brain (mechanically) from the jagged ridges inside the skull.
What can happen after brain damage?
Swelling of the brain causing an increase in intracranial pressure (ICP). This decreases blood flow causing hypoxic damage due to compressed arteries.
What are the meninges?
Wrap around the brain and spinal cord
What are the meninges composed of?
Dura mater, pia mater, arachnoid mater
Describe the dura mater
is composed of 2 layers of dense fibrous tissues called the periosteal layer and the meningeal layer (which forms in-foldings to separate areas of the brain)
Describe the pia mater
sits on top of the grey matter of the brain
Describe the arachnoid mater/subarachnoid space
Contains arachnoid villi which are one-way valves where CSF can drain into venous circulation
The subarachnoid space is located between the pia and arachnoid mater. CSF flows in this space
Describe where CSF is made in the brain
In the ventricles, specifically the choroid plexus which is made up of glial and epidymal cells
Where can CSF be found in the body?
Brain, spinal cord
How many ventricles are in the brain?
4 i.e.: 2 lateral ventricles, 3rd and 4th ventricles
What is hydrocephelous?
A blockage of the arachnoid villi causing swelling of the skull to allow the brain to swell. Only occurs in children as their skull bones have not full fused together
What is normal intracranial pressure (ICP)?
7-15 mmHg (adult)
3-7 mmHg (child)
What is high ICP?
20-30 mmHg (mild increase)
>40 mmHg (lift-threatening)
What can raised ICP cause?
Decreased blood flow and hypoxic damage
What can cause raised ICP in adults?
Haemorrhagic stroke, infection, blocked shunt
What is the blood brain barrier (BBB) made up of?
Glial cells, astrocytes, epindymemal cells, oligodendrocytes
What is the function of the blood brain barrier?
Forms a protective barrier between the blood and the brain. Tight junctions along the BBB allow oxygen, carbon dioxide and glucose into the brain. It keeps out viruses, fungi, bateria