Neuro Physiology and Anatomy Flashcards
Hyperopia (farsighted)
Eye cannot focus on nearby objects because light focuses behind the retina (due to shortness of the eye or an inability of the lens to become convex)
Tx: convex lens
Myopia (nearsighted)
Eye cannot focus on distant objects because light focuses in front of the retina (due to length of the eye or an inability of the lens to flatten out)
Tx: biconcave lens
Astigmatism
Abnormal curvature of cornea, resulting in different refractive power at different axes
Tx: cylindric lens
Presbyopia
Decrease in focusing ability during accommodation due to sclerosis and decreased elasticity; often age-related. The “near point” (closest point on which one can focus by accommodation of the lens) moves farther from the eye
Tx: convex lens
CN III damage
Affects eye movement (SR, IR, MR, IO), pupillary constriction (sphincter pupillae), accommodation (ciliary muscle), eyelid opening (levator palpebrae)
Causes “down and out” eye, pupillary dilation, loss of accommodation, and ptosis
CN IV damage
Affects SO; eye looks upward with adduction
Head tilt toward the side of the lesion / the unaffected eye
CN VI damage
Affects LR; eye looks medially
Lesion in somatosensory cortex
Contralateral sensory deficit; may be associated with UPN-type weakness, visual field deficits, and aphasia
Lesion in VPL
Contralateral sensory deficit; larger deficits may involve the internal capsule (hemiparesis)
Lesion in the lateral pons or lateral medulla
Affects the anterolateral pathways and spinal trigeminal nucleus
Contralateral loss of pain and T sensation in the body, and Ipsilateral loss of pain and T sensation in the face
Lesion in the medial medulla
Affects the medial lemniscus
Contralateral loss of vibration and joint position sense
Lateral hypothalamus
Produces orexin (hypocretin), which stimulates hunger and wakefulness. Inhibited by leptin.
Destruction causes anorexia or failure to thrive in infants, and narcolepsy (due to decreased orexin/hypocretin production).
Ventromedial hypothalamus
Controls satiety. Stimulated by leptin. Destruction (e.g. craniopharyngioma) causes hyperphagia and aggressive, savage behavior.
Anterior hypothalamus
Lowers T via PSNS. Stimulated by increased heat.
Location of osmoreceptors (controls ADH release)
“A/C” of the hypothalamus
Posterior hypothalamus
Increases T via sympathetics. Stimulated by decreased heat.
Suprachiasmatic nucleus of the hypothalamus
Responsible for circadian rhythm
Supraoptic nucleus of hypothalamus
Produces ADH
Paraventricular nucleus of hypothalamus
Produces oxytocin
Ventroposteriolateral (VPL) nucleus of the thalamus
Pressure, touch, vibration and proprioception (from the dorsal columns/medial lemniscus); pain and T (from the spinothalamic)
Projects to primary somatosensory cortex
Ventroposteriomedial (VPM) nucleus of the thalamus
Face sensation and taste from the trigeminal and gustatory pathway (via the solitary nucleus)
Projects to primary somatosensory cortex
“Make-up goes on the face”
Lateral geniculate nucleus (LGN) of the thalamus
Vision via CN II
Projects to calcarine sulcus (primary visual cortex)
“L = Light”
Medial geniculate nucleus (MGN) of the thalamus
Hearing via superior olive and inferior colliculus of tectum
Projects to auditory cortex of temporal lobe
“M=Music”
Ventrolateral (VL) nucleus of the thalamus
Motor via basal ganglia and cerebellum
Projects to motor cortex