Neuro Med Sheet

Question 1

Meningitis:

if H. flu or N. meningitis

Answer 1

Ceftriaxone (Rocephin)

2g IV q 12-24 hrs x 7 days

Question 2

Ceftriaxone

AE/CI

Answer 2

AE: diarrhea, neutropenia, thrombocytopenia, platelet dysfunction

CI: neonates with high bilirubin, hepatic/renal impairment, seizure disorders

Question 3

Meningitis (if S. pneumo with mic >=2 ceph. resistant) add this to Ceftriaxone

Answer 3

Vancomycin (Vancocin)

15 mg/kg IV q8h x 10-14 days

Question 4

Vancomycin AE

Answer 4

AE: nephrotoxicity, ototoxicity, red man syndrome, hypokalemia, neutropenia, thrombocytopenia

Question 5

Meningitis Prophylaxis (2)

Answer 5

Rifampin (Rifadin) 600 mg PO qd x 4 days - if H. flu
600 mg PO q12 hrs x 4 – if. N. mening.

Ceftriaxone (Rocephin) – 250 mg IM x 1

Question 6

Rifampin AE

Answer 6

AE: agranulocytosis, hepatic toxicity, renal failure, nephrotoxicity

Question 7

Seizure (benzo)

Answer 7

Lorazepam (Ativan) – 0.1 mg/kg IV; may repeat after 5-10 min

Question 8

Lorazepam

AE/CI

Answer 8

AE: sedation, ataxia, confusion

CI: respiratory insufficiency, narrow angle glaucoma

Question 9

Seizure (Topiramate)

Answer 9

Topiramate (Topamax) – 200-400 mg qd

Question 10

Topiramate

AE/CI

Answer 10

AE: decreased appetite & cognition, speech diff., HA, diplopia, WT. LOSS

CI: PREGNANCY

Question 11

Migraine Prophylaxis (Topiramate)

Answer 11

50-200 mg/day (in two div. doses

Question 12

Seizure (VPA)

Answer 12

Valproic Acid (Depakote) – 1000-3000 mg

Question 13

Valproic Acid

AE/CI

Answer 13

AE: tremor, wt. GAIN, hepatic failure, thrombocytopenia, N/V, hair loss, ataxia

CI: PREGNANCY, liver disease, bleeding disorder

Question 14

Migraine Prophylaxis (VPA)

Answer 14

Valproic Acid (Depakote) 500-1500 mg qd (in two div. doses)

Question 15

Parkinson’s Disease

Answer 15

Carbidopa/Levadopa (Sinimet) – 300-1,000 mg PO qd

Question 16

Carbidopa/Levadopa AE

Answer 16

AE: agitation, confusion, insomnia, psychosis, HA, dizziness

Question 17

Multiple Sclerosis

Answer 17

Interferon B-1A (Rebif) – 44 mcg SQ 3x/wk

Question 18

Interferon B-1A (AE)

Answer 18

AE: depression, HA, flu-like sx, injection site rxn

Question 19

Migraine (SC, PO, and Nasal dosages)

Answer 19

Sumatriptan (Imitrex) –
SC: 6 mg – MR after 1 hr (max 12 mg/d)
PO: 25 mg x 1 – MR after 2 hrs (max 100 mg/d)
Nasal: 5, 10, 20 x 1 – MR after 2 hr (max 40 mg/d)

Question 20

Sumatriptan (AE)

Answer 20

AE: dizziness, sensation of warmth, chest fullness, nausea

Question 21

Migraine Prophylaxis (TCA)

Answer 21

Amitriptyline (Elavil) – 30-150 mg PO qhs

Question 22

Amitriptyline

AE/CI

Answer 22

AE: drowsiness, wt. GAIN, serotonin syndrome w/ Triptans, anti-SLUD
CI: urinary retention, heart block