Neuro (ENT, Derm, Opthal) Flashcards
Otitis Ext Sx
Painful, Itchy, Inflamm,
Discharging Ear
(esp in swimmers/adults)
Otitis Ext Mx
Micro-suction pus/debris,
(If Bact: Top Gentamicin)
(If Fungal: Top Anti-fungal)
Acute Otitis Med Sx + Ex
Dull Pain (w/ ear pulling),
Discharge (once pain stops),
Fever,
(Preceeding Viral Inf)
Otoscope:
Bulging, non-mobile tympanic membrane with yellow/red discolouration
Acute Otitis Med Mx, Admission criteria + Surg
Analgesia, Delay Abx
(If confirmed/Otorrhoea or < 2yo w/ Bilat Inf: Amox)
Admit if:
< 3mo w/ fever > 38,
< 6mo w/ fever > 39
(If recurrent/ET dysfunction: Grommet Surg),
(If TM Perf: Myringoplasty)
Glue Ear Patho + Sx
(Otitis Media w/ Effusion):
Dysfunctional ET following OM causes build-up of Fluid w/in Middle Ear
(CN) Hearing loss,
Ear Pain w/ fullness,
Discharge,
Recurrent ENT Inf
Glue Ear Ix + Mx
Otoscopy (Normal Ex does not Excl)
Mx:
Act Observation for 6-12wks
Assess hearing w/ Pure Tone Audiometry x2 before Refer
Surg (Grommets, Hearing Aid)
Otosclerosis Features
Early, progressive (CN) hearing loss w/
(+) FHx,
Tinnitus
Otosclerosis Mx
Hearing aids,
Stapedectomy
TM Perforation Sx + Mx
Pain
Conductive hearing loss
Mx:
Watch and wait (w/ water caution)
(If > 6 months: Myringoplasty)
BPPV Patho + Sx
Otoliths within semicircular canals
Transient (secs/mins), Positional (occurs with head movements) Vertigo
(no tinnitus/hearing loss)
BPPV Diagnosis + Mx
Diagnosis:
Dix-Hallpike Test
Mx:
Epley and Brandt-Daroff Manouvres
Menieres D Patho + Sx
Excess Fluid w/in Inner Ear
Sx: Episodic vertigo (mins - hours) w/ N+V Tinnitus, Aural fullness Fluctuating SN hearing loss (progress -> permanent) (Gen Imbalance)
Menieres D Mx:
Diet
Med - 3
Surg - 5
Diet (Reduce salt, chocolate, alcohol, caffeine)
Med:
Thiazide diuretics,
Betahistine
Prochlorperazine (vestibular sedative)
Surgery: Grommets Dexamethasone middle ear injection Endolymphatic sac decompression Gentamicin injection (causes vestibular destruction) Surg Labryninthectomy
Vestibular Neuritis Patho + Sx
Inflamm of Vestibular Nerve
Sx:
Severe Vertigo (days) w/ N+V
Horizontal nystagmus
(If Hearing affected, Tinnitus: Labyrinthitis)
Vestibular neuritis Mx
Vestibular Sedatives (Prochlorperazine)
Sudden-onset hearing loss Ix
Tuning fork (Weber + Rinnes)
Pure Tone Audiogram
Tympanogram
MRI (excl. Acoustic neuroma)
Acute Rhinosinusitis Org + Length/Timing
Viral (RhinoV, InfluenzaV): Sx resolve w/in 5 days
Bact (S.Pneum, H.Influenzae): Sx persist > 5 days
Acute Rhinosinusitis Mx
Analgesia, Nasal decongestants
If > 10 days:
- Top/Nasal Steroid
- Delayed PO Abx (wait 1wk for Sx to resolve: Phenoxymethylpenicillin 5 days)
Chronic Rhinosinusitis Def + Ix
Def: > 12wks
Skin prick (Allergy) test
(If Unilat: Biopsy)
(If Atypical features/Surg planned: CT sinuses)
Chronic Rhinosinusitis Mx:
Conservative
Med
Surg
Conservative: Allergy avoidance, Nasal douching (IN saline sol)
Med: Antihistamines Top nasal steroids, PO steroids (1wk) PO Abx ImmunoTx (for Severe Allergies)
Surg:
Nasal Polypectomy
Funct Endoscopic Sinus Surg
Allergic Rhinosinusitis Classification:
Duration
Severity
Duration:
Intermittent: Sx < 4 days a week, < 4 wks
Persistant: Sx > 4 days a week, > 4 wks
Severity:
Mild: No Impairment of Daily Activities
M2S: Troublesome Sx
H+N Lumps Red Flags - 5
Hard, Fixed, Irreg Lumps Associated Otalgia, Dysphagia, Stridor or Hoarse voice Epistaxis, Unilat nasal congestion Cranial N palsies B Sx
H+N Lumps Ix
USS +/- FNA
CT/MRI
(If Lymphoma suspected: Core biopsy, Open LN biopsy)
BCC Features
Skin coloured (Clear/Pink), rolled borders Surface Telangiectasia (+/- ulcer in centre) Slowly evolves (non-healing scab) (Found on H+N)
BCC Mx
Surgical excision
Radiotherapy (when surgery not appropriate)
Micrographic surgery (progressive excision until specimen free) – for High risk, recurrent tumours
SCC Features
In situ: Erythematous + Scaly,
Invasive: Exophytic Ulcer (w/ Ill-defined border)
Grows quickly + Easily Friable
SCC Mx
Surgical excision,
Micrographic surgery
Radiotherapy (large, nonresectable tumours)
Chemotherapy (metastatic disease)
Melanoma Features
Asymmetrical Irregular border Deeply pigmented (Brown) > 6mm Evolving (+ Metastasises)
Melanoma Mx
Surgical excision
Immunotherapy/chemotherapy (metastatic disease)
Eczema Sx
Itchy, erythematous, dry, scaly patches
w/ Lichenification
Infants (Face and Limb extensors), Adults (Limb Flexures)
Eczema Ix
Allergy (patch) testing
Serum IgE
Eczema Mx
Avoid triggers (pets, soaps, infections)
Emollients
Acute flareups: Top Steroids
Severe Pruritus: Antihistamines (Piriton)
Psoriasis Sx
Itchy/Painful, Erythematous, Scaly, Well-defined patches/plaques (Adults: Ext)
Koebner Phenomen (new skin lesions at sites of skin injury) Auspitz sign (Excoriation => Bleeding)
(Nail changes: pitting, onchyolysis)
Psoriasis Mx
Emollients (Reduce scales)
Vitamin D analogues
Topical steroids (8wks max)
Acne Mx
Mild: Top Abx/Retinoid + BPO
Mod: Oral antibiotics (Tetracyclines)
Severe: Oral retinoids (Isotretinoin)
(PCOS: antiandrogens – COCP/Spironolactone)
(Epiduo: Top Adapalene + BPO, Duac: Top Clindamycin + BPO)
Steroid SE:
Local - 5
Systemic - 6
Local: Skin thinning, striae, telangiectasia, acne, allergic contact dermatitis
Systemic: Cushing’s, immunosuppression, hypertension, diabetes, osteoporosis, cataracts
Retinoids SE
Dry lips/skin/eyes
Myalgia, arthralgia
Hypercholesteraemia, hypertriglyceridaemia
Teratogenic (require contraception before prescribing)
Suicidal Ideation
Pupil Reflexes:
Afferent
Efferent
Afferent:
CN-II -> Pre-tectal Nucleus
Pre-tectal N -> EWN (Bilat)
Efferent:
EWN -> CN-III ->
Ciliary Ganglion - >
Sphincter Pupillae (+ Ciliary muscles)
Pupil Defects:
Complete
Partial
Complete Optic N:
Light shone in eye -> No direct/consensual response
Light shone in other eye -> Consensual response
Partial Optic N: (RAPD)
Slowed direct response, normal consensual response
Swinging light test: Constriction (Light shone contralaterally), Dilation (Light shone ipsilaterally)
Blepharitis Patho, Sx + Mx
Inf eyelids (Inflamm w/ yellow crust)
Mx:
Lid hygiene, Abx
Chalazion vs Stye
Chalazion: (Blocked Meibomian glands):
Painless, Above lash line
Stye: (Inf Meibomian glands):
Painful, Edge of lash line
Ant Uveitis Sx
(Iris + ciliary body): Red, painful eye (w/ irreg pupil), Reduced VA, Floaters, Photophobia
Ant Uveitis Mx
Mx:
Steroid drops (Reduce Inflamm),
Cyclopentolate (Anti-musc) drops
(Prevent adhesions + reduce pain: Cycloplegia/Ciliary paralysis)
Inf Keratitis Sx
(Cornea): Red, painful eye w/ hypopyon (Pus w/in Ant chamber), Reduced VA (Corneal oedema), Photophobia, (HSV keratitis: Dendrite pattern w/ Fluoroscein)
Inf Keratitis Mx
Mx:
Remove contacts, Steroid drops
IV Abx/Antivirals/Antifungals,
(Avoid steroid drops w/ HSV keratitis)
Scleritis Sx, Associations + Mx
Red, tender, painful eye
(Pain => Headache => Waking at night)
(Associated w/ RA, GCA/Vasculitis, Ank Spondylo, SLE, IBD)
Mx:
Urgent referral
Subconjunctival Haem Sx
Unilateral, localised, discrete bleed
No inflammation, pain, discharge
Normal vision
(Pt may be on anticoags/antiplatelets)
Subconjunctival Haem Mx
Reassure
Check BP, clotting/INR
Hyphema Def + Sx
Bleed within anterior chamber (following trauma) =>
Red eye (w/ Meniscus)
Severely reduced vision
Stained cornea (with increased IOP)
Hyphema Mx
Urgent referral
Bedrest and eyepatch
Amarosis Fugax Sx, Ix + Mx
Temp monocular vision loss (returns to normal w/in hrs) +/- Focal Neuro Def
Carotid Doppler
Normal Fundoscopy
Mx:
Aspirin 300mg + Referral
CRVO Sx + Ex
Sudden painless vision loss w/ RAPD
Blood + Thunder:
Dil torturous V, Cotton-wool spots, Swollen Optic disc, Retinal Oedema + Haem
CRAO Sx + Ex
Sudden painless vision loss w/ RAPD
Cherry-Red
Pale retina w/ red spot on fovea
Optic Neuritis Patho + Sx + Ex
(CN-II Inflamm):
Sudden vision loss w/ RAPD (+/- Blur/Haze/Central Scotoma, Desaturated colours) Orbital pain (esp w/ eye movements)
O/E:
Swollen optic disc
(If normal: Retrobulbar neuritis)
Optic Neuritis Mx
IV steroids + Urgent referral
Ischaemic Optic Neuropathy Sx + Ex
Temp painless vision loss w/ RAPD,
(GCA Sx + B Sx)
O/E:
Swollen, pale optic disc
Ischaemic Optic Neuropathy Ix + Mx
Fundoscopy
CRP/ESR
Temporal artery biopsy (GCA)
IV Methylpred 1g
ARMD Patho:
Dry
Wet
Dry AMD:
Gradual Accumulation of waste products/fatty deposits (Drusen) bilaterally
Wet AMD:
Sudden Choroidal neovascularisation (w/ macular oedema and haemorrhage)
(+/- Retinal detachment)
ARMD Features
Painless (central) vision loss (Normal peripheral and colour vision) Dry: Progressive (years), Bilateral, (+/- progress to Wet AMD)
Wet:
Rapid,
Unilateral,
(Visual distortion: Scotomas, Metamorphopsia)
Retinal Detachment Patho + Sx
Separation of Sensitive Retina layer from RPE
Painless loss of vision
Recent history of floaters/flashes/shadows
Fundoscopic changes in HT
Mild - 2
Mod - 4
Severe - 1
Mild:
Gen/focal arteriolar narrowing
AV nicking
Moderate: Retinal haemorrhage Micro-aneurysms Cotton wool spots Hard exudates
Severe:
Optic disc swelling
Fundoscopic changes in DM Background - 2 Pre-proliferative - 2 Proliferative - 1 (Diabetic Maculopathy)
Background:
Microaneurysms,
Retinal haemorrhages
Preproliferative:
Cotton wool spots,
Exudates
Proliferative:
Retinal neovascularisation
(Diabetic maculopathy: Macular oedema)
Diabetic Retinopathy Mx
Pan-retinal photocoagulation (PRP): Reduce VEGF
Aqueous Humour Prod Control
A2-Adren-R:
Decrease production of Aqueous Humour
B2-Adren-R:
Increase production of Aqueous Humour
Drugs affecting IOP
Alpha-Agonists, Beta-Blockers
(Decrease Production of Aqueous Humour)
Carbonic Anhydrase Inhibitors (Acetazolamide)
(Decrease Production of Aqueous Humour)
Prostaglandins (Latanoprost)
(Increase Outflow of Aqueous Humour)
Parasympathomimetic (Pilocarpine)
(Increase Outflow of Aqueous Humour)
Glaucoma Features :
Open-angle, Chronic Closed
Acute Closed
Open-angle/Chronic Closed:
Initially asymptomatic
Bilat, progress visual field loss
(Periph -> centre)
Acute Closed:
Unilat, painful, Inflamm eye (w/ Irreg, semi-dilated + unresponsive pupil)
Blurry vision, Haloes,
(Frontal headache, N+V, Photophobia)
Glaucoma Ix
Tonometry (Raised IOP)
Fundoscopy (Cupping, Optic disc pallor/Haem)
Gonioscopy (Reduced Iridocorneal angle)
Open angle glaucoma Mx
Top Prostaglandins (Latanoprost)
Surg (Improve drainage):
Laser trabeculoplasty
Surg Trabeculectomy
Chronic Closed angle glaucoma Mx
Laser (Periph) Iridotomy
Surg Trabeculectomy
(Top Lantanoprost/PG’s: Maintenance)
Acute Closed angle Mx:
Supp
Med
Surg
Supportive:
Urgent referral, Analgesia and anti-emetic
Med: Parasympathomimetic (Pilocarpine) A2-Adren-R Agonist (Apraclonidine) Beta-blocker (Timolol) Carbonic anhydrase inhibitor (Acetazolamide) Diuretic (IV Mannitol – esp if N+V)
Surg:
Ant chamber Paracentesis
Laser (Periph) Iridotomy
Retinoblastoma Sx
Lack of red reflex (Abnormal white reflection), Change in colour of Iris Red, inflamed (painless) Eye Squint/Poor vision, Diff controlling EOM
Retinoblastoma Ix + Mx
Fundoscopy, USS
Mx:
Urgent referral,
Small: Laser Photocoag/ThermaTx, CryoTx
Large: Radio/ChemoTx + Removal of Eye
Def: Myopia Hyperopia Astigmatism Anisometropia
Myopia: (Short-sightedness):
Long eye, Wide Lens (Cataracts)
=> (-) Biconcave Lens (Divergence)
Hyperopia: (Long-sightedness):
Short eye, Lack of Lens (Aphakia)
=> (+) Biconvex Lens (Convergence)
Astigmatism (Assymetrical Eyeball):
Mx: Cyclindrical Lens
Anisometropia (Different refractive powers btw 2 eyes)
Allergic Conjunctivitis Sx
Itchy, painful, red eyes (Bilat) w/ watery discharge
Swollen conjunctiva
History of Atopy (pruritus, eczema, asthma)
Allergic Conjunctivitis Mx
Remove allergen
Topical antihistamines, cool compresses
(If no change in 3 days: refer)
Bact Conjunctivitis Sx
Bilateral, red, painful eye with purulent discharge
Systemically well
Bact Conjunctivitis Mx
Topical antibiotics (5 days) w/ Regular eye hygiene (If vision affected or worsens: refer)
Viral Conjunctivitis Sx
(Recent Eye/URTI infection)
Burning sensation and watery discharge (Increased lacrimation)
Swollen conjunctiva
Preauricular lymphadenopathy
Viral Conjunctivitis Mx
(Self resolving – weeks)
Cool compresses, Lubrication fluid, Top ABx drops (Secondary Bact Inf)
(If reduced VA, photophobia, > 3wks: refer)
Sarcoidosis Features
Purple rash/lesions on face
(Tender) Bilat Lymphadenopathy
Acne Rosaecea Feature indicating Severe + Mx
(If Plaques: Severe)
M2M: Top Metronidazole
Severe/Resistant: PO Tetracyclines