Neuro diagnostics Flashcards
1
Q
radiographs
A
- fasted pre- and post-prandial bile acids
- ACTH stim test
- Dexamethasone suppression test
- urine protein:creatinine ratio
- paired insulin and glucose levels
2
Q
infectious testing: peripheral blood or serum
A
- Cryptococcus neoformans (cats)
- endemic opportunistic fungus
- respiratory entry, but neurotropic organism
- Latex Capsular Agglutination Test (LCAT)-very sensitive and specific
- Leptomeningitis-eosinophils on CSF
3
Q
infectious testing: CSF
A
- toxoplasma gondii
- neospora canis
- cryptococcus neoformans
- distemper virus
4
Q
infectious testing: regional diseases
A
Coccidioides, Blastomycoses, Hepatozoon…
5
Q
infectious testing: PCR panels
A
respiratory (cats), neurological (dogs)…
6
Q
radiographs
A
- survey analysis
- other systemic disease
- anatomy
- boney lesions
- will NOT see neural structures
- will NOT see discs (unless mineralized)
7
Q
ultrasound
A
- sound waves do NOT penetrate bone
- persistent fontanelle-a window
8
Q
myelography
A
- survey spinal rads
- intrathecal injection
- repeat radiographic series
- complications
- arrest
- seizures (higher if >20 kgs or cisternal)
- worsening neuro status (chemical meningitis)
- non-ionic, iodinated, low osmolality
9
Q
computed tomography
A
- more sensitive than conventional rads
- contrast arises from different degrees of attenuation of x-rays (tissue density)
- rapid, inexpensive, can be performed under sedation
10
Q
magnetic resonance imaging
A
- signal comes from protons which behave differently depending on environment
- very esnsitive for soft tissue resolution
- slow
- requires general anesthesia
- can’t use with pacemaker or region of interest has prior implants
- gadolinium-based contrast, paramagnetic
11
Q
when to MRI
A
- most brain diseases
- intramedullary spinal diseases, tumors
- non-chondrodystrophoid or Type II IVDD
12
Q
when to CT
A
- fractures, boney disease
- mineralized, Type I IVDD
- poor for caudal fossa and lumbosacral area
13
Q
CSF
A
- bathes brain and spinal cord
- produced by choroid plexus
- carbonic anhydrase
- drained by arachnoid villi into venous sinuses
- ultrafiltrate of plasma (almost water)
14
Q
CSF tap
A
- considerations
- competency
- requires general anesthesia
- rapid degradation of cells
- very sensitive, not specific
- greater meningeal or ependymal involvement, the more abnormal CSF
15
Q
CSF tap contraindications
A
- increased intracranial pressure
- lack of comfort/competency with procedure