Neuro Flashcards
_____ pain:
Prickling, stabbing
Carried by myelinated fibers
good localization
Fast pain
Refers to localized dilation in a blood vessel wall that can rupture and lead to hemorrhage
Aneurysm
Provides a relay station for informatin to and from the cerebral cortex
Thalamus
Name the 3 connective tissue membranes that cover and protect the CNS
- Dura Mater
- double layer membrane surrounding the brain
- Arachnoid Mater
- threadlike extensions span subarachnoid space (filled with CSF)
- Pia Mater
- clings tightly to the surface of braine and spinal cord
Cholinergic receptors include _____ and _____
- Nicotinic
-
Muscarinic
- blocked by atropine
Afferent: _____
Efferent: _____
Somatic _____
Autonomic: _____
Afferent: Sensory
Efferent: Motor
Somatic: Voluntary
Autonomic: Involuntary
Unmyelinated fibers
slow pain (visceral pain), hot and cold, itch
Intergrate and link information with higher motor neurons, where response can be initiated
Association Area
Infection and inflammation of brain tissue or spinal cord
Encephalitis
There are four ventricles containing _____
Which ventricle is associated with lumbar punctures
There are four ventricles containing CSF
The fourth ventricle connecting the subarachnoid space and central canal of the spinal cord, this is what you obtain during a LP (done at L3/L4)
Sudden focal neurological deficit from a vascular disorder
Nontraumatic disruption of the blood supply to an area of the brain
Define Ischemic, Hemorrhagic, TIA
Stroke
- Ischemic: results from obstructed blood flow
- can lead to ischemia, potentially irreversible necrosis, cerebral infarction
- results from thrombosis formation or embolism in cerebral vessel
- Hemorrhagic: results from intracranial hemorrhage
- occurs deep in the parenchyma or near surface of braine
- HTN as an underlying cause
- TIA: due to ischemia
- short-lived and resolve completely
- The master gland of body
- Regulates the pituitary gland
- Regulates water balance, hunger-satiety cycle, overall metabolism, body temperature
- Controls Autonomic Nervous System
Hypothalamus
Governs skeletal muscle activity and controls balance and equilibrium
Cerebellum
_____ fibers : Ascend the dorsal columns
Myelinated fibers ascend the dorsal columns
Activation of an autoimmune response, usually by infection with bacteria (CMV)
Attack and destruction of eripheral nerves involves damage to myelin and can result in paralysis as well as sensory and autonomic disturbances
Most patients fully recover within a year
Guillain-Barre syndrome
The process by which a neuron conveys information to another cell such as another neuron, a muscle cell, or a gland
Synaptic Transmission
Ascends contralateral (Crosses at spinal cord at point of entry)
Carry slow pain and temperature information
Anteriolateral systems
The functional cells of the nervous sytem that contain the cell body, dendrites, and axons
Neurons
What is considered a secondary brain injury
Occurs as the body responds to a primary injury
Can include:
-
ischemia
- reduces availability of glucose and removal of waste
-
hypoxia
- decreased oxygen
-
increased ICP
- fluid accumulation d/t inflmmatory process
-
edema
- accumulation of fluids
A form of spinal cord injury involving a partial (hemi) transection of the anterior and posterior spinal cord that can result in compromise to PNS function and responses
Brown-Sequard Syndrome
- Lossof voluntary motor function from the corticospinal tract
- Proprioception loss from ipsilateral side of body
- contralateral loss of pain and temperature sensations from lateral spinothalamic tracts for all levels below lesion
- Results in intracranial hemorrhage
- Osccurs deep in the parenchyma or near surface of the braine
- often has hypertension as an underlying cause
Hemorrhagic stroke
Fast and slow pain (arthritis or a sprained ankle)
Deep Somatic Pain
_____:
Slow pain (internal)
(chest pain due to an MI)
Visceral
Myotatic or stretch reflexes control the position of the body in space
Proprioception
Neurotransmitter; cholinergic transmission
Acetylcholine
The disruption of blood flow to the brain causes _____ and neurological dysfunction and include ____ or _____
Cerebrovascular Disease (CVD): Disruption of blood flow to the brain causes cerebrovascular brain injury and neurological dysfunction and include TIA’s or strokes
Causes: hypertension and hyperlipidemia
Efferent (motor) PNS
- _____ system
- skeletal muscle
- _____ system
- Smooth
- Cardiac muscle
- Glands
- Somatic
- Autonomic
What is the function of the brainstem?
Regulates basic and essential functions of the body
- Forms the reticular formation or reticular activating system (RAS)
- Consciousness, sleep wake cycle, respiratory and cardiovascular control centers
Forms of TBI that may be reversible or self-resolving depending upon the severity of the injury
Concussions and Contusions
- Concussion
- caused by sudden movement of brain as during a sports injury, MVC, fall
- Diffuse injury
- Cerebral contusion
- Bruising of brain tissue
What are the four major regions of the brain
- Cerebral hemispheres
- Diencephalon
- Brain stem
- Cerebellum
- Results from obstructed blood flow (thrombus/embolus)
- Can lead to ischemia, potentially irreversible necrosis, cerebral infarction
- May also be caused by systemic hypoperfusion (shock)
Ischemic Stroke
What is considered a primary brain injury
Refers to the structural damage at the moment of trauma to neurons, glial cells, and blood vessels
Fast myelinated fibers
touch, proprioception, pressure
Infection of the meninges
Meningitis
Can be caused by bacterial infection or virus
After reaching the _____ the information is transmitted to association areas in the cerebral cortex
Somatosensory Cortex
An afferent neuron and all of the receptors that send information along it
Sensory Unit
Inflammatory autoimmune disease that destroys myelin surrounding axons of CNS neurons
Multiple Sclerosis
The area of skin supplied by a single spinal nerve transmitting to a dorsal root ganglion and spinal cord segment, where we do testing
Dermatome
The brainstem includes the _____ and _____
Pons and Medulla
A condition characterized by loss of motor neurons
Amyotrphic Lateral Sclerosis (ALS)
The supporting cells in the PNS that produce myelin to facility rapid conduction of an action potential
Schwann cells
A state of awareness and orientation to surroundings, and the ability to respond to stimuli
Consciousness
The ionic changes that allow conduction of information along the length of the axon
Action potentials
Slow myelinated fibers
touch, temperature, fast pain
Ascends ipsilateral (crosses in medulla)
Carry proprioception, vibration, deep pressure, touch
Dorsal columns
Degenerative disease of the CNS characterized by movement disorder
Cause: death of dopamine-producing cells of the basal ganglia
S/S: tremor, bradykinesia, rigidity, postural instability, dementia, depression
Parkinson’s Disease
The CNS is protected by what four structures?
Bone
Meninges
Cerebrospinal fluid
Blood-Brain barrier
Neurons:
_____ receive stimuli
_____ contain myelin (“white matter”)
- Dendrites receive stimuli
- stimuli pass down axons
- Schwann cells contain myelin (“white matter”)
- help increase speed of impulse transmission
Adrenergic receptors include _____ and _____
- Alpha-adrenergic (vasoconstriction)
-
Beta-adrenergic (vasodilation)
- blocked by propanolol
The spinal cord relays _____ sensory information to the brain and _____ somatic information from the brain
Afferent; Efferent
_____ pain:
Buring, aching
Carried by unmyelinated fibers
Poor localization
Slow Pain
TBI may result in _____ into the cranial vault from epidural, subdural, or intracerebral sources
Hemorrhage
Enter the spinal cord or brain and synapses on an interneuron
Afferent Neurons
An area (on the body surface) that sends information along a single afferent neuron
Receptive Field
The diencephalon contain the _____ and _____
thalamus and hypothalamus
- Head injury and subsequent damage to brain, possibly cranial nerves as well
- give rise to spinal cord injuries
- A major cause of death and disability
- Major causes include falls, MVCs, violence
- May be closed or open
Traumatic Brain Injury
Cerebral Hemispheres and their functions
- Frontal- movement, phonation
- Parietal- sensory
- Temporal- auditory
- long term memory
- Occipital- visual
- Limbic- emotions
- in cerebrum
Neurotransmitter; Adrenergic transmission
Norepinephrine