Neuro 4 PG Flashcards

1
Q

how are action potentials produced and how are they conducted along the axon?

A

through the action of voltage-activated ion channels

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2
Q

what are voltage-activated ion channels

A

ion channels that open or close in response to changes in the level of the membrane potential

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3
Q

why is membrane potential of of a neuron at rest is relatively constant despite the high pressure acting to drive Na+ ions into the cell?

A

This is because the resting membrane is relatively impermeable to Na+ ions and because those few that do pass in are pumped out

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4
Q

what marks the end of the rising phase in action potential?

A

the sodium channel closing

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5
Q

what is the beginning of depolarization in action potential?

A

the continued leaving of K+ ions.

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6
Q

what ions does action potential involve?

A

only those right next to the membrane

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7
Q

what is the absolute refectory period?

A

a brief period of about 1 to 2 milliseconds after the initiation of an action potential during which it is ­impossible to elicit a second one.

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8
Q

what is the relative refractory period?

A

the period during which it is possible to fire the neuron again but only by applying higher-than-­normal levels of stimulation. The end of the relative refractory period is the point at which the amount of stimulation ­necessary to fire a neuron returns to baseline.

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9
Q

what are the two important ways that axons differ from conduction of EPSPs and IPSPs

A

-conduction of action potentials along an axon is nondecremental (action potentials do not grow weaker as they travel through axonal membranes)
-action potentials are conducted more slowly than postsynaptic potentials

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10
Q

the conduction os EPSPs and IPSPs is

A

passive

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11
Q

axonal conduction of action potential is

A

largely active

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12
Q

antidromic conductions

A

if electrical stimulation of sufficient intensity is applied to the terminal end of an axon, an action potential will be generated and will travel along the axon back to the cell body

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13
Q

orthodromic conduction

A

axonal conduction in the natural direction

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14
Q

where can myelinated axons pass through the axonal membrane

A

at the nodes of Ranvier

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15
Q

what is saltatory conduction

A

the transmission of action potentials in myelinated axons

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16
Q

where do axodendritic synapses terminate

A

dendritic spines

17
Q

what are axiomatic synapses

A

synapses of axon terminal buttons on somas

18
Q

what can axoaxonic synapses do

A

mediate presynaptic facilitation and inhibition

19
Q

directed synapses

A

synapse at which the site of a neurotransmitter release and the sire of neurotransmitter reception are in close proximity

20
Q

non directed synapse

A

synapse at which the site of release is at some distance from the site of reception
-also referred to as string-of-bead synapses

21
Q

what are large neurotransmitters

A

neuropeptides

22
Q

neuropeptides

A

short amino acid chains composed of between 3 and 36 amino acids; short proteins

23
Q

coexistence

A

many neurons contain two neurotransmitters

24
Q

exocytosis

A

process of neurotransmitter release

25
Q

reuptake

A

The drawing back into the terminal button of neurotransmitter molecules after their release into the synapse; the most common mechanism for deactivating a released neurotransmitter.