Neuro 4 PG Flashcards
how are action potentials produced and how are they conducted along the axon?
through the action of voltage-activated ion channels
what are voltage-activated ion channels
ion channels that open or close in response to changes in the level of the membrane potential
why is membrane potential of of a neuron at rest is relatively constant despite the high pressure acting to drive Na+ ions into the cell?
This is because the resting membrane is relatively impermeable to Na+ ions and because those few that do pass in are pumped out
what marks the end of the rising phase in action potential?
the sodium channel closing
what is the beginning of depolarization in action potential?
the continued leaving of K+ ions.
what ions does action potential involve?
only those right next to the membrane
what is the absolute refectory period?
a brief period of about 1 to 2 milliseconds after the initiation of an action potential during which it is impossible to elicit a second one.
what is the relative refractory period?
the period during which it is possible to fire the neuron again but only by applying higher-than-normal levels of stimulation. The end of the relative refractory period is the point at which the amount of stimulation necessary to fire a neuron returns to baseline.
what are the two important ways that axons differ from conduction of EPSPs and IPSPs
-conduction of action potentials along an axon is nondecremental (action potentials do not grow weaker as they travel through axonal membranes)
-action potentials are conducted more slowly than postsynaptic potentials
the conduction os EPSPs and IPSPs is
passive
axonal conduction of action potential is
largely active
antidromic conductions
if electrical stimulation of sufficient intensity is applied to the terminal end of an axon, an action potential will be generated and will travel along the axon back to the cell body
orthodromic conduction
axonal conduction in the natural direction
where can myelinated axons pass through the axonal membrane
at the nodes of Ranvier
what is saltatory conduction
the transmission of action potentials in myelinated axons