Neuro Flashcards
Ddx light-near dissociation
- Dorsal midbrain syndrome 2. Adies pupil 3. Argylle robertson sx
What are the 4 findings in dorsal midbrain syndrome?
- Impaired upgaze 2. Bilat lid retraction (colliers sign) 3. Headache 4. Dizziness
Ddx cn3 palsy
1.Myasthenia (can cause any cranial neurop but never involves pupil) 2. Ischemia 3. Trauma to frontal bone 4. Ms 5. Tumor
Whats a cecocentral scotoma on vf mean?
Optic nerve disorder eg compressive toxic optic neuritis
Arcuate scotoma mean
Nfl defect along horiz raphe = glaucoma
Whats a cecocentral scotoma?
Blind spot connect to central fixation
What does homonomous defect mean?
Is it on the same side of the vertical
What does it mean if the vf defect is vertical?
Its at the chiasm or behind The more congruous the defect the further back it is
Bitemporal hemianopsia what should you ask about?
Galactorrhea Menstrual irregulation Weight fluctuation Get mri with gad
Whats the ddx of a central scotoma on vf?
Csr Amd Toxic on Lebers hereditary on Infiltrative
Pie in the sky defect Where localize to? What to order?
Temporal lobe (meyer loop) Order mri w and wo gad to look for tumor or stroke
Bulateral homonmous inferior quadrantopsia Where localize to? What test to do?
Parietal lobe Check okn drum bc it tests smooth pusuit and if you lose parietal lobe you lose smooth pursuit
What does homonomous mean?
Vf in Both eyes Occurs on same side of the vertical
Where does arcuate or altitudnal defects localize to?
Optic nerve
What does congruity mean?
How similar the two sides are. The more posterior you get in the brain the more congruous the defects are
Atropine poisoning symptoms
Anti cholonergic so acts like a sympathetic drug Big pupils Decr Salivation Hot as a hare Dry as a bone Mad as a hatter
Mg
Mg no ach Give tensilon = ach If adverse rxn Give atropine (anti ach)
Whats the rx for atropine toxicity?
Tensilon (physostigmine)
What does organophosphate poisoning look like?
Organophosphate are anti ach Just like atropine Can also look like mg (no ach) So give tensilon
Ddx mg
Organophosphate poisoning Attopine poisoning Lambert eaton(no release of ach into the synapse) Miller fisher (varient of guillien barre that starts w eyes) Guillian barre Cpeo (mitochondrial do) Oculopharengeal muscular dystrophy Venoms Botulism poisoning- toxin prevent release from presynaptic terminal (likr lambert eaton)
Rx of mg
Mestinon 60 or 180 Prednisone Thymectomy
How do you work upmg?
Tensilon test (10mg) Have atropine ready Check anti ach ab Check anti musk ab Cxr to look for thymoma Ro other autoimmune do
What cancer is lambert eaton ass w?
Small cell lung cancer
left homonomous inferior quadrantopia, R parietal defect
ALTITUNAL DEFECT
could be optic neuritis or NAION
CENTRAL SCOTOMA OU
ddx:
csr
toxic optic neuropathy
amd
lebers hereditary optic neuropathy
infiltrative
R meyers loop in temporal lobe
get mri w and wo gad
bitemporal defect is chiasmal lesion until proven otherwise
VF defects in both eyes densist part respects the horizontal midline- could be occipital lobe or could be paracentral scotoma
inferior altitudnal defect (altitudnal defects do NOT cross the horizontal
Right superior homonomous hemianopsia involving superior quadrant
unilateral right central scotoma- either a problem with the macula or ON
unilateral right VF defect with central sparing could be functional tunnel vision, if this were bilateral would think RP. can check for fxl vision loss w tangent screen
clover leaf pattern
bilateral paracentral scotoma OR Right homonomous incongruous hemianopia from L parietal or occipital lesion
junctional scotoma, think about mass in chiasm
defects ou either bitemporal hemianopia or a jxnal scotoma
Left parietal lobe lesion
left homonomous congruous defects could be occipital lesion b/c so congruous
Right temporal lobe lesion
left homonomous incongruous hemianopsia, must be retrochiasmal right tract lesion
check an apd left eye and for a lesion in the right tract
enlarged BS OU or possibly bitemporal hemianopsia, check to see if nerves are swollen, if so it could be enlarged blind spot
non homonomous, not bi-temporal, could represent superior altitudnal defect- sequential optic neuropathy
what is this?
pituitary adenoma
whats this?
midbrain tumor