Neuro Flashcards

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1
Q

What is Prevalence

A

The proportion of people with a clinical condition at a particular point, or within a specific period in time

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2
Q

Define Incidence

A

Proportion of people who develop a clinical condition within a specific period of time.

these people are initially free of the condition.

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3
Q

Define a tests sensitivity

A

the probability that a test will return a positive result among people who have the disease.

Low sensitivity = fail to detect disease when present.

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4
Q

Define test specificity

A

the probability that a test will be negative amend individuals free of the disease.

High specificity = does not detect disease when disease is not present

low specificity = detects disease when disease not present.

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5
Q

Formula for sensitivity

A

a/ (a + c)

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6
Q

formula specificity

A

d/ (b+d)

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7
Q

Positive predictive value definition & formula

A

How confident you can be that the disease is present.

= a/(a+b)

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8
Q

Negative predictive value formula + definition

A

how confident you can be that you do not have the disease

= d/(c+d)

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9
Q

Define Hemiplegia (or paresis)

A

Paralysis or weakness of muscles of the arm, leg and sometimes face on one side of the body

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10
Q

Causes of hemiplegia (or paresis)

A

Internal capsule, cerebral hemisphere, spinal cord hemisection;

rarely a high cervical spinal cord lesion

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11
Q

define Monoplegia (or paresis)

A

paralysis or weakness of all of the muscles in one limb, arm or leg

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12
Q

causes of monoplegia (or paresis)

A

spinal cord lesion
lesion in cerebral hemisphere
peripheral neuropothy

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13
Q

Define paraplegia and its causes (or paresis)

A

paralysis of muscles in both legs.

Caused by spinal cord lesion and peripheral neuropathy

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14
Q

Define triplegia (or paresis) & Causes

A

Hemiplegia or paresis & paralysis or weakness of one limb on the opposite side of the body.

Caused by:
High cervical spinal cord lesion or multiple lesions

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15
Q

Define tetraplegia (or paresis), quadriplegia and causes

A

Paralysis or weakness of all four extremities.

Causes:
lesion in high cervical spinal cord, brain stem, or cerebral hemispheres
acute polyneuropathy or radiculopathy
myopathy

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16
Q

Characteristics Duchenne’s Muscular Dystrophy

A
  • X-Linked recessive
  • progressive, fatal, characterised by weakness
  • little or no dystrophin produced in body = degradation muscle fibres
  • pseudo-hypertrophy: muscle cells deteriorate and regenerate until this cycle is no longer possible and they are then replaced with fat and connective tissue
17
Q

Characteristics Becker Muscular Dystrophy

A

X-Linked Recessive

Similar to Duchenes but not as severe and children live longer

18
Q

Characteristics Myotonic Muscular Dystrophy

A

Autosomal dominant

19
Q

Characteristics limb-girdle Muscular Dystrophy

A

Autosomal recessive

20
Q

Characteristics Myasthenia Gravis

A

Affects Neuromuscular transmission - autoimmune- loss of ACh receptors - possibly caused by viruses & thyroid gland abnormalities

Characteristic feature = cannot keep yes open (ptosis) & oropharyngeal abnormalities

21
Q

What is the peripheral nervous system?

A

the structures outside the pail membrane brainstem and spinal cord