Neuro

Question 1

How long after presentation of SAH should an LP done looking for xanthochromia?

Answer 1

At least 12h

Question 2

Schizo patient develops tremor, abnormal facial, tongue, body movements ?cause

Answer 2

Common SEs of Chlorpromazine (phenothiazine antipsychotic)

Question 3

Hand tingling

Wasting of interossei and abductor digiti minimi (lies medial)

Answer 3

Ulnar nerve lesion

Question 4

Wide based gait
Unable to walk heel-toe

What type of gait and important causes?

Answer 4

Ataxis gait

Causes:
Cerebellar lesions
Hypothyroidism
Inherited eg. Friedrich’s

Question 5

Writer’s cramp features and treatment

Answer 5

Focal dystonia causing involuntary contraction and repetitive movements
Writing for shorter and shorter periods
30-50yo

Rx: beta blockers, botulinum toxin

Question 6

Progressive lower motor neurone disease (no sensory features)

Aged 4?
Aged ~6mo

Which chromosome is abnormal

Answer 6

4yo: Kugelberg Welander SMA
<6mo: Werdnigg-Hoffman SMA

c5

Question 7

Which cerebral haemorrhage is associated with taring of middle meningeal artery/vein?

Answer 7

Extradural

Question 8

Signs of Brown-Sequard

Answer 8

hemisection:

Contralateral pain/temperature loss
Ipsilateral vibration and proprioceptive loss and weakness

Question 9

Males or females higher risk for delirium?

Answer 9

Male

Question 10

Most common cause of stroke in children?

Definitive Ix?

Answer 10

Vaso-occlusive crisis in SCA

Hb electrophoresis

Question 11

Treatment of relapse in MS?

Answer 11

0.5-1g methylpred IV/PO for 3-5 days

NB. Does not reduce frequency of relapse or progression of disease

Question 12

Disease modifying therapy in MS

Answer 12

Natalizumab
Interferon

NB. reduce relapse rate

Question 13

Riluzole MoA, indication, benefits?

Answer 13

Glutamate ANTAGonist
Treatment of ALS MND
Delays progression to tracheostomy + ventilation by ~3mo

Question 14

Reflexes in MG

Answer 14

normal

Question 15

Role of thymectomy in MG

Answer 15

Beneficial to ALL patients, even if no evidence of thymoma

Question 16

Rx of MG

Answer 16

PYRIDOSTIGMINE
Steroids
Azathioprine
Thymectomy (beneficial for all MG)
Plasma exchange

Question 17

Gower’s sign

Answer 17

Using hands/arms to walk up body up to standing

Sign of DMD

Question 18

DMD Ix

Answer 18

CK
Genetic testing
Muscle Bx

Question 19

Essential Ix for dementia

Answer 19

Neuroimaging essential prior to diagnosing dementia

Question 20

First line Rx for <12yo migraine

Answer 20

NSAID

Triptan not licensed for <12yo

Question 21

What is cataplexy?

Answer 21

Sudden onset loss of tone following strong emotion