Neuro Flashcards

1
Q

Shuffling gait

A

Parkinson’s

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2
Q

Broad-based gait

A

Cerebellar ataxia

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3
Q

Falling backwards

A

Midline cerebellar ataxia (damage to middle of cerebellum or vermis)

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4
Q

Stamping gait

A

Sensory ataxia

“High stepping” gait, relying on vision

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5
Q

Distal vs proximal limb weakness gait signs

A

Distal: slap foot on ground
Proximal: waddling

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6
Q

When do you get waddling gait?

A

Polymyositis, muscular dystrophies

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7
Q

What is gait apraxia?

A

Frontal lobe disease (diffuse cerebrovascular disease, normal pressure hydrocephalus), walking skills become disorganized, despite normal motor and sensory function when examined

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8
Q

How does the gait look in gait apraxia? How does this differ form Parkinsons?

A

Small shuffling, hesitant to start

Arm swing and posture are normal

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9
Q

3 inhibitors neurotransmitters

A

GABA, histamine, glycine

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10
Q

Damage where gives you Broco’s aphasia?

A

Left frontal cortex

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11
Q

Parietal lesions features

A

Contralateral sensory loss/neglect

Agraphaesthesia

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12
Q

Failure to recognize faces

A

Parietal

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13
Q

Complex partial seziures and memory disturbances lesion

A

Temporal lobe

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14
Q

Global aphasia describes what? When do you get?

A

Combination of Broca’s and Wernicke’s

After a severe left hemisphere infarct

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15
Q

Dysarthria describes

A

Disordered articulation - slurred speech

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16
Q

Episodic memory

A

Long-term memory for events

17
Q

Semantic memory

A

Knowledge of words

18
Q

Implicit memory

A

Not conscious - how to ride a bike

19
Q

Working memory

A

Short-term memory

20
Q

Long term memory is divided into

A

Implicit (not conscious) and explicit (conscious)

21
Q

Explicit memory is divided into

A

Episodic (for events) and semantic (for facts, words, knowledge)

22
Q

Procedural memory falls under _______ memory

23
Q

Fast voluntary eye movements originate where?

A

Frontal lobes, then they descend and cross in the pons to end in the centre for lateral gaze (paramedic pontine reticular formation)

24
Q

Each paramedic pontine reticular formation also receives input from

A

Ipsilateral occipital cortex

Vestibular nuclei

25
Damage to what leads to INO
MLF
26
What happens in INO?
In right INO, there is a lesion of the right MLF, on attempted left lateral gaze, the right eye fails to adduct
27
Failure of upgrade is caused by
Dorsal midbrain lesions
28
Acute lesion of one pyramidal tract causes
``` Flaccid paralysis Increased tone (UMN) signs follows ```
29
Hemiparesis definition
Weakness of the limbs on one side - usually caused by a lesion in the brain and occasionally in the cord
30
Hemiparesis symptoms depending on levels within the corticospinal tract
Motor cortex: weakness and/or loss of skilled movement confined to one contralateral limb or part of a limb - defect in cognitive function and focal epilepsy may occur Internal capsule: sudden, dense, contralateral hemiplegia Pons: Adjacent features (VIth and VIIth cranial nerve) are involved Spinal cord: Ipsilateral UMN lesion
31
Spastic paraparesis indicates
Bilateral damage to corticospinal pathways - weakness and spasticity (flaccidity in initial phase)
32
Extrapyramidal system is a general term for
Basal ganglia motor systems: corpus striatum, subthalmig nucleus, substantia nigra
33
2 features of extrapyramidal disorders
1. Bradykinesia (reduction in speed of movement) | 2. Involuntary hyperkinetic movements (tremor, chorea, dystonia, tics, myoclonus)
34
Part of extrapyramidal system affected in Parkinson's vs Huntington's
Substantia Nigra, Putamen, Cortex | Corpus striatum
35
Hemiballism results from a lesion in the
Subthalmig nucleus
36
Cerebellum modulates
Coordination and learned movement patterns (rather than speed)
37
UMN is used interchangeably with
Pyramidal