Neuro 10.3 Strokes Flashcards

1
Q

What is the definition of a stroke?

A

The damaging or killing of brain cells starved of oxygen as a result of the blood supply to that part of the brain being cut off

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2
Q

What is a TIA?

A

A stroke that recovers within 24 hours from the onset of symptoms

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3
Q

Name possible locations for origins of clots

A
  • carotid arteries
  • vertebral/basilar arteries
  • heart: valvular disease/AF
  • the aorta
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4
Q

What is encompassed by the anterior circulation and posterior circulation?

A
  • Fed by internal carotid
  • Encompasses the ACA and MCA
  • Fed from vertebral arteries
  • Encompasses: PCA, cerebellar arteries, arteries supplying the brainstem
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5
Q

In anterior circulation:

  • What artery has been affected?
  • What area of brain does it supply?
  • What does this part of brain do?
A
  • Anterior cerebral artery
  • supplies: medial aspects of frontal and parietal lobe and anterior part of corpus callosum
  • supplies motor and sensory function to lower limb and genitals
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6
Q

How will a patient present in anterior cerebral artery stroke?

A
  • Motor loss: contralateral, lower limb affected more than upper limb, initially get flaccid paralysis followed later by spasticity (UMN signs)
  • Sensory loss: contralateral, loss of all sensory modalities in the lower limb (spinothalamic and dorsal column affected equally)
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7
Q

What are two important areas to know about when talking about Ant cerebral artery strokes?

A
  • Paracentral lobules: area of medial cortex that controls voluntary portion of mircturition, damage leads to loss of voluntary control
  • Corpus callosum: damage to ACA can lead to split brain syndrome/alien hand syndrome
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8
Q

Middle cerebral artery strokes

-what area does the brain supply?

A
  • Superior temporal lobe, lateral aspects of frontal and parietal lobe
  • basal ganglia, internal capsule, macular cortex
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9
Q

Middle cerebral artery strokes

  • what does this part of the brain do?
  • what occurs in main trunk occlusions?
A
  • MCA supplies all of the homonculus not supplied by ACA (not legs or genitals)
  • MTOs cause considerable cerebral oedema - may lead to coma/death
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10
Q

Middle cerebral artery strokes

-How will the patient present?

A
  • Motor loss: contralateral, upper limb and face affected more than lower limb. Initially get flaccid paralysis followed later by spasticity (UMN signs)
  • Sensory loss: contralateral, loss of all sensory modalities in the upper limb and face.
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11
Q

Middle cerebral artery strokes

-Why is the location of occlusion important?

A
  • Proximal occlusion: will affected lateral motor cortex and internal capsule (carries descending motor fibres from the enterito of the motor cortex), t/f face, arm and leg may be affected (lenticulostriate arteries are affected)
  • More distal occlusion (after lenticulostriate arteries): spares the internal capsule but still damages the lateral motor cortex t/f only arm and face are affected
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12
Q

Middle cerebral artery strokes

-What are the visual effects?

A
  • Proximal occlusion of MCA: contralateral homonymous hemianopia (temporal and parietal radiations are lost)
  • Distal occlusion of MCA: contralateral homonymous superior or inferior quadrantonopia (very rare)
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13
Q

Middle cerebral artery strokes

-how is speech affected?

A
  • Speech centres normally reside in LHS of brain, but symptoms depend on which branch of MCA is affected and which is the dominant hemisphere
  • If dominant hemisphere is affected
    • Proximal occlusion: global aphasia caused by main trunk occlusion
    • Distal occlusion: Brocca’s (expressive) alphasia (leads to motor loss) and/or Wernicke’s (receptor) aphasia (pt speaks rubbish)
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14
Q

Middle cerebral artery strokes

-Speech: what happens if the non-dominant (right is most likely) side is affected?

A
  • Get hemispatial neglect
  • tacticle extinction: touch both sides together - get extinction of LHS stimulus
  • visual extinction
  • Anosognosia
  • *Are without Disease knowledge and deny they have any form of disability
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15
Q

Posterior cerebral artery

-What area of the brain does it supply?

A

-inferior temporal lobe and occipital lobe

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16
Q

Posterior cerebral artery

-What does this area of the brain do? How will the patient present?

A
  • Contains the visual cortex

- In stroke, the patent will present with contralateral homonymous hemianopia with macular sparing

17
Q

Anterior Cerebellar artery stroke

  • What does this part of the brain do?
  • How will the patient present?
A
  • Coordinates all movements

- Disdiadochokinesia, Ataxia, Nystagms, Intention tremor, slurred speech and hypotonia

18
Q

What do the cerebellar arteries also supply? What is the difference between a proximal and distal occlusion of the cerebellar arteries?

A
  • The brainstem
  • A proximal occlusion may cause brainstem and cerebellar signs (eg pontine infarction is proximal)
  • A distal occlusion may cause cerebellar signs alone
19
Q

What sort of deficits will you have if you damage brain supply to the brainstem?

A
  • Will damage ascending/descending tracts affecting the contralateral side of the body
  • The cranial nerve nuclei are located in brainstem so damage to them will cause ipsilateral signs
20
Q

Basilar artery strokes

-What area is affected?

A

-Same area as posterior cerebral artery - inferior temporal lobes and posterior cerebral artery.

21
Q

Basilar artery strokes

-What will a distal occlusion cause?

A
  • Bilateral occipital lobe infarction: pt becomes blind
  • bilateral thalamic infarction: pt is anaesthetised
  • Bilateral midbrain infarction: affects cranial nerves
  • Any stroke involving the basilar artery will cause bilateral symptoms because we only have 1 basilar artery
22
Q

Basilar artery strokes

-What will a proximal occlusion cause?

A
  • Locked in syndrome: get pontine artery occlusion, corti-cospinal pathway in ventral pons leads to quadrapledia
  • Lose cortico-bulbar pathway (pyramidal tract
  • Retain consciousness and ascending sensory info
23
Q

Lacunar strokes - lenticulostriate artery

  • What is this a branch of?
  • What part of the brain does it supply?
  • What does this part of body do?
A
  • MCA
  • Internal capsule (carries down motor fibres to supply body muscles) and basal ganglia
  • The posterior limb carries descending motor fibres
24
Q

Lenticulostriate artery strokes

-How will the patient present?

A
  • Isolated (to 1 side), contralateral paralysis
  • Initially will be flaccid, followed by spasticity
  • Involves face, upper limb and lower limb
25
Q

Left thalamoperforator artery stroke

  • What is this a branch of?
  • What part of the brain does it supply?
  • What does this part of body do?
A
  • small branch of PCA
  • Supplies part of the thalamus
  • The thalamus relays sensory information to the post-central gyrus (somatosensory cortex)
26
Q

Left thalamoperforator artery stroke

-How will the patient present?

A

-Isolated (to 1 side), contralateral sensory loss (all modalities) in the face, upper limb and lower limb

27
Q

What imaging modality is best for strokes and timings?

A
  • CT is best for acute phase - helps find the bleed

- MRI is better for post-acute phase (takes too long for acute phase)

28
Q

What are things that could mimic a stroke?

A
  • Hypoglycaemia
  • epilepsy
  • migraine (hemiplegic)
  • intracranial tumours/infections