Neural Transmission Flashcards
Types of slices
Horizontal (flat across), Sagittal (backwards) and Coronal (from right to left)
Directions
Dorsal = op, Ventral = bottom, Superior = above, Inferior = below, Lateral = further from midline, Medial = towards the midline, Anterior = towards front, Posterior = towards back.
Brain structure
Gyrus = Protuberance on surface, Sulcus = fold or groove separating gyri, Fissure = long, deep sulcus.
Location
Proximal = close to, Distal = far from, Ipsilateral = same hemisphere, Contralateral = opposite hemisphere.
CNS + PNS
CNS = Brain + spinal cord.
PNS = Somatic nervous system (voluntary muscles and senses) + Autonomic nervous system (involuntary muscles - sympathetic: “fight or flight”, parasympathetic: “rest and digest”)
Neurons + Gila
Neurons = receive and transmit information, Gila = serve many varied functions (e.g., insulation, support)
All neurons consist of a cell body.
A collection of cell bodies in PNS = ganglion, in CNS = nucleus.
Nucleus
DNA + protein synthesis including neurotransmitters
Soma
Cell body + nucleus.
Dendrites
Receives signals from other neurons.
Dendrites are bumpy, they have spines which grow and shrink as a result of repeated activations (e.g., through learning).
Axon hillock
Very top of the axon.
Common ‘trigger site’ for action potentials.
Although sometimes action potentials may be triggered at the next segment of the axon.
Axons
Carries action potentials.
Transmits signals to other neurons.
Axon terminals
End of axon.
Ends in the terminal buttons.
Terminal buttons
Release neurotransmitters into the synapse.
Myelin sheath
Made of glial cells.
Insulates the axon.
Increases speed of action potential propogation.
Nodes of ranvier
Gaps in the myelin sheath.
Site of action potential regeneration in myelinated axons.
Afferent/Efferent?
Relative term referring to where the axon is going from or to.
The axon is efferent from the pre-synaptic neuron and afferent to the post-synaptic neurons.
Synapse
The gap between two (or more) neurons where messages are chemically transmitted.
The nervous system can be seen as a chain of neurons linked together at synapses.
Types of Glial cells
Astrocytes (star-shaped) - involved in response to injury of the CNS; regulate blood flow to some neurons.
Oligodendrocytes - form myelin in CNS (Schwann cells form myelin in PNS)
Microglia - involved in immune response in the CNS.
Brain anatomy divisions
Hindbrain (rhombencephalon), Midbrain (mesencephalon) + Forebrain (prosencephalon)
Hindbrain
Medulla, pons + cerebellum.
Enlarged extension of the spinal cord into the skull.
Controls vital reflexes - breathing, heartrate, vomiting, salivating, coughing, sneezing - through the cranial nerves.
Cranial nerves control sensations from the head, muscle movements of the head and most parasympathetic output to the organs.
Receptors and muscles of the head are connected to the brain via 12 pairs of cranial nerves.
Each cranial nerve originates in a nucleus (cluster of neurons) that integrates sensory information, regulates the motor output, or both.
The nuclei for cranial nerves V to XII are located in the medulla and pons: those for cranial nerves I to IV are in the midbrain and forebrain.
The pons lies anterior to the medulla.
In the pons, axons from each half of the brain cross to the opposite side of the spinal cord, so that the left hemisphere controls the muscles of the right side of the body and vice versa.
The cerebellum is a large hindbrain structure with many deep folds.
It is mainly known for its role in movement and coordination, but also has cognitive functions.
Midbrain
Tectum, superior colliculus + inferior colliculus.
Superior colliculus is important for vision.
Inferior colliculus is important for hearing.
Several nuclei and tracts occur in the midbrain - including the substantia nigra.
Forebrain
Most prominent part of mammalian brain, consisting of two cerebral hemispheres (left and right). - hemispheres receive sensory input, and control muscles on the opposite side of the body.
Consists of: limbic system, diencephalon, basal ganglia and cerebral cortex.