Neural Mechanisms Controlling Eating Behaviour Flashcards
Ventromedial Hypothalamus (VMH)
The satiety centre - inhibits feeding
Anand and Brobeck 1951
Found that a lesion to the lateral hypothalamus causes aphagia in rats, concluded it was the feeding centre.
Lateral Hypothalamus (LH)
The feeding centre - stimulates feeding
Ghrelin
A hormone that is secreted from the stomach.
Released when the stomach is empty.
Sends signals to stimulate feelings of hunger.
Where is ghrelin secreted from?
The stomach
Which hormone signals you are hungry?
Ghrelin
Cummings et al. 2004 procedure
6 participants
Ate lunch
Ghrelin levels measured through blood samples taken every 5 minutes
Assessed their levels of hunger every 30 minutes
What did Cummings et al. 2004 find?
Blood ghrelin levels fell immediately after eating, then slowly began to rise and peaked when participants requested their evening meal.
Ghrelin levels also closely correlated with the degree of hunger reported by 5 out of the 6 participants.
Cummings et al. 2004 evaluation
Extraneous variables such as time and context cues eliminated
Small sample size
Androcentric
Correlation not causation
Physical and psychological harm - but informed consent given.
Which study investigated the changes in blood ghrelin levels over time between meals?
Cummings et al. 2004
Where is CCK released from?
The duodenum
What does CCK do?
CCK sends satiety signals to the hypothalamus in the presence of food to inhibit feeding.
Glucostat theory
Suggests glucose levels are a key signal of satiety and hunger.
However, it has been found that the levels aren’t significant enough, and although diabetics have high levels of glucose, they still have normal appetites.
What is the main short-term factor which inhibits the intake of food?
CCK being released from the duodenum when food is present
What is leptin?
A hormone that is released from adipocytes to indicate body weight.
When there is more body fat, more leptin is released and the hypothalamus reduces feeding.