Neural Crest Cells

Question 1

The timing of the expression of these two is critical in discriminating between neural plate, epidermis, placode, and neural crest cell tissue.

Answer 1

BMP and Wnt

Question 2

If BMP and Wnt expression are both continuous…

Answer 2

Ectoderm –> Epidermal

Question 3

If Wnts induce BMPs and Wnt is kept OFF…

Answer 3

Anterior Placodes

Question 4

If Wnts induce BMPs and Wnt is kept ON…

Answer 4

Neural Crest Cells

Question 5

BMP Antagonists

Answer 5

Noggin and FGF

Question 6

If BMP antagonists block BMP…

Answer 6

Ectoderm –> Neural Plate Cells

Question 7

Neural Plate Border Specifiers

Answer 7

Pax3
Pax7
Distalless

Question 8

Neural Plate induces _____.

Answer 8

Transcription Factors/Neural Plate Border Specifiers

Question 9

Neural Plate Border Specifiers induce _____.

Answer 9

Neural Crest Specifiers

Question 10

Neural Crest Specifiers that induce neuroepithelial cells to undergo epithelial-mesenchymal transition and delaminate from neuroepithelium

Answer 10

Sox9 and Snail

Question 11

Required for the survival of trunk neural crest cells after delamination

Answer 11

Sox9

Question 12

Inhibition of _____ inhibits NCC specification.

Answer 12

Foxd3

Question 13

Sox10 is for delamination and differentiation of NCCs, and it binds to…

Answer 13

MITF
Small G Proteins
Cell Surface Receptors