Neural Conduction and Synaptic Transmission Flashcards

1
Q

what do acetylchlone receptors bind to?

A

nicotine and muscarinic

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2
Q

Is nicotine ionotropic of metabotropic?

A

ionotropic

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3
Q

is muscarinic metabotropic or ionotropic?

A

metabotropic

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4
Q

what is the main ingredient of belladonna

A

Atropine

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5
Q

what is atropine?

A

a receptor blocker that exerts its antagonist effects by binding to muscarinic receptors preventing the effect of acetylcholine

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6
Q

What is curare?

A

a receptor blocker at cholinergic synapses acting at nicotine receptors

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7
Q

What is Botox?

A

a neurotoxin released by bacteriu often found in spoiled food

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8
Q

what antagonist effect does botox have?

A

it is a nicotine antagonist

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9
Q

why is botox deadly?

A

it blocks the release of acetylcholine at neuromuscular junctions

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10
Q

Recurrent collateral inhibition is mediated by

A

Renshaw cells

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11
Q

What does constituent cognitive process refer to?

A

each complex cognitive process results from the combined activity of simple cognitive processes

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12
Q

Principle of Antithesis

A

opposite messages are signalled by opposite movements and postures

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13
Q

Inhibitory Postsynaptic Potential are?

A

postsynaptic hyperpolarisations

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14
Q

What do IPSPs do?

A

decrease the likelihood of a neuron firing

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15
Q

What do EPSPs do?

A

increase the likelihood of a neuron firing

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16
Q

what are Excitatory postsynaptic potentials

A

postsynaptic depolarization’s

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17
Q

what is the axon hillock?

A

conical structure at the junction between the cell body and the axon

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18
Q

What are axodendritic synapses?

A

synapses of axon terminal buttons on dendrites

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19
Q

What is salutatory conduction?

A

transmission of action potentials in myelination axons

20
Q

What are interneurons?

A

composed of cell bodies or of axons

21
Q

what are bipolar neurons?

A

two processes extending from its cell body

22
Q

what are unipolar neurons?

A

one process extending from it

23
Q

what are multipolar neurons?

A

more than two processes extending from its body

24
Q

What are axosomatic synapses?

A

synapses of axon terminal buttons on somas

25
Q

What is a axoaxonic synapse?

A

mediate presynaptic facilitation and inhibition

26
Q

What is dendrodendritic synapses?

A

capable of transmission in either direction

27
Q

what is directed synapse in comparison to non-directed synapse?

A

site of neurotransmitter reception is in close proximity in comparison to far away

28
Q

what is exocytosis?

A

the process of neurotransmitter release

29
Q

what is a ligand?

A

a molecule that bind to another

30
Q

what does endogenous mean?

A

naturally occurring in the body

31
Q

what is a tripartite synapse?

A

synaptic transmission that depends on communication among three cells via gap junctions

32
Q

what is a metabotropic receptor?

A

a receptor associated with signal proteins and g-proteins

33
Q

what is an ionotropic receptor?

A

a receptor associated with ligand-activated ion channels

34
Q

what are voltage activated ion channels?

A

ion channels that open/close in response to changes in levels of membrane potential

35
Q

pressure to enter the cell comes from?

A

electrostatic pressure or random motion

36
Q

what happens when molecules bind to postsynaptic?

A

depolarize of hyperpolarise

37
Q

molecules binding to postsynaptic receptors have..

A

graded responses

38
Q

Where are neurotransmitter released from?

A

terminal buttons

39
Q

what kind of release are IPSPs and EPSPs?

A

detrimental

40
Q

What it the absolute refractory period?

A

where it is impossible to elicit a second action potential

41
Q

what is a relative refractory period?

A

a second action potential is possible but requires a higher level of depolarization

42
Q

what are large neurotransmitters?

A

neuropeptides

43
Q

Glutamate, asparatate, glycine and GABA are examples of?

A

amino acid neurotransmitters

44
Q

monoamines in comparison to amino acids are?

A

larger and slower

45
Q

What are examples of catecholamine monoamines?

A

dopamine, norepinephrine

46
Q

where are catecholamines synthesised?

A

the tyrosine

47
Q

What type of monoamine is serotonin?

A

Idolamine