neural and hormonal mechanisms in aggression Flashcards
Reactivity of what system predicts aggressive behaviour?
limbic cystem
what is the limbic system?
subcortical structures in the brain including the hypothalamus and amygdala
what is the most important structure in the limbic system?
amygdala
why is the amygdala the most important structure in limbic system?
plays a key role in how humans and non-human animals assess and respond to environmental threats and challenges
the reactivity of the _______ in humans has proven to be an important predictor of aggressive behaviour
amygdala
who conducted a study that shows a strong association between aggression and amygdala activity?
Gospic et al
how did Gospic et al show a strong association between aggression and amygdala activity?
- Gospic carried out brain scans (fMRI) on participants in a lab-based game designed to provoke aggression- the Ultimatum game
- scans revealed that aggressive reactions were associated with a fast and heightened response by amygdala
- a benzodiazepine drug which reduces arousal of the autonomic nervous system taken before the game halved the number of aggressive reactions and decreased amygdala activity
- showing a strong association between aggression and amygdala activity
apart from limbic system, what is the other neural mechanism in aggression?
low levels of serotonin results in reduced self-control and increased aggression
normal levels of serotonin in the orbitofrontal cortex have ________ effects
inhibitory (they are linked with reduced firing of neurones which is associated with greater behavioural self-control; decreases serotonin may disturb this mechanism, reducing self-control, increasing impulsive behaviours)
who conducted research into the comparison of levels of serotonin metabolite (breakdown by-product) called 5-HIAA in the cerebrospinal fluid of violent impulsive and violent non-impulsive offenders?
Virkkunen et al
what did Virkkunen et al find?
levels of serotonin metabolite significantly lower in impulsive offenders, who also suffered more sleep irregularities; this is relevant because serotonin regulates sleepy patterns. Disturbance of this pattern strongly implies disruption of serotonin functioning, supporting its role in reactive aggression
what is the hormonal mechanism involved in aggression?
testosterone
testosterone is a hormone responsible for
the development of masculine features and also helps to regulate social behaviour via its influence on areas of the brain involved in aggression
evidence for an association between testosterone and aggression in humans comes from studies of prison populations e.g. violent offenders such as
Dolan et al
what did Dolan et al find?
a positive correlation between testosterone levels and aggressive behaviours in a sample of 60 male offenders in UK maximum security prisons; these men mostly suffered from personality disorders e.g. psychopathy and had histories of impulsively violent behaviour