neumuscular Flashcards
Multiple sclerosis
Slow progressive disease related to demyelination affecting brain and spinal cord causing multiple and varied neurological disorders
Pathology of MS
Immune system attacks myelination of the nerve fibers, causing damage and exposing nerve fibers- this slows or blocks signals trying to be transmitted
Although the body tries to repair the myelination scars develop and these nerves seem to die off sooner than normal
How long do remissions last for MS
Months–> years
exacerbation can be debilitating
S/S of MS
Vary between person
Paresthesia- extremities, trunk, unilateral
Motor function- start in 1 extremity and move up
Weakness, loss of motion, clumsiness, spasticity
Visual disturbances- diplopia, scotomas
Bladder issues- incontinence, retention, urgency
erectile dysfunction
mood liability- depression weeeping
MANIA- Late phase
Dx of MS
Usually by exclusions of other disorders MRI- Plaques CT- contrast may show lesions CSF- IgG, lymphocytes, protein will be increased EEG- delayed visual response
Common treatment for MS?
Immunosuppressants
Which medication is used to decrease relapses
Interferon Ib (Betaseron)
Which DMT is used to tx MS
Ocrelizmab
Which medications are used as muscle relaxants for MS
Baclofen
diazapam- valium
Muscle spasticity?
Botox
Urinary incontinence for MS
oxybuytonin
Urinary retention
Bethanechol (Urecholine)
Symptomatic therapy for MS?
Exercise, physical, OT/PT psycho therapy
What should be avoided for Pt w MS
Heating pads, testing water for baths/showers, avoid heat exacerbations
Safety teaching for mobility for MS
Walking to increase control of gait, assistive devices prn
Continue mobility to increase strength
Exercise as tolerated w periods of rest
