Nervous Tissue Flashcards

1
Q

most numerous of the neuroglial cells

A

Astrocytes

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2
Q

have a euchromatic nucleus that is considerably smaller than that of the neurons. Their principal role is to clear neurotransmitters from within the synaptic cleft, and to that end, their attenuated processes surround every synaptic junction in the CNS.

A

Astrocytes

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3
Q

Their processes contribute to the blood-brain barrier and surround all penetrating blood vessels and all the free surfaces of the brain and spinal cord.

A

Astrocytes

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4
Q

The extensive network of astrocytes and their processes is integrated by ___ _____, and they signal each other using _____.

A

gap junctions; calcium

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5
Q

enlarge and form the scar that follows damage to areas of nervous tissue.

A

Astrocytes

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6
Q

The three main types of glial cells; location?

A

Astrocytes, oligodendrocytes, microglia

CNS

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7
Q

small cells with a heterochromatic nucleus that form and maintain central myelin for axons in the central nervous system

A

Oligodendrocytes

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8
Q

small cells with a heterochromatic nucleus. They perform functions similar to those of the macrophage. They are mobile within the brain and can multiply when the brain is damaged

A

Microglia

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9
Q

What are the origins of all three neuroglia

A

Oligodendrocytes and astrocytes - ectodermal tissue

microglial - hematopoietic stem cells; mesodermal tissue

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10
Q

Which of the neuroglia has the smaller more heterochromatic nuclei?

A

Oligodendrocyte and microglia

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11
Q

Which of the neuroglia has the larger more euchromatic nuclei?

A

Astrocytes

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12
Q

Expand to form the glial limitans

A

astrocytes

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13
Q

List the supporting cells of the PNS

A

Schwann cells

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14
Q

What are the origins of Schwann cells?

A

They originate in the neural crest of the developing embryo and migrate throughout the body in parallel with the developing peripheral nervous system.

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15
Q

What is the relationship between neurons and Schwann cells?

A

Every surface of a neuron in the periphery is in contact with a Schwann cell.

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16
Q

The cell bodies of the ganglion cells are encapsulated by a layer of Schwann cells, known classically as ___________ in that location.

A

Satellite cells

17
Q

envelop bundles of unmyelinated axons, providing physical support and protection

A

Schwann cells

18
Q

Following damage to axons, __________ phagocytose the debris of degenerating fibers and establish guidance paths for axon regeneration

A

Schwann cells

19
Q

the endoneurium consists of _____ and _______ of the nerve fiber

A

reticular fibers and the external lamina

20
Q

Describe the perineurium

A

is a fiber-reinforced layer of fibroblast-like cells that surrounds fascicles of axons

21
Q

Describe the epineurium; what is it made up of?

A

outer covering that binds the multiple nerve fascicles into a larger peripheral nerve.

The epineurium is a dense irregular connective tissue with many collagen fibers arranged in parallel to the fascicle.

22
Q

The presence of a perineurium is one way to differentiate between _____________, ____________________, and peripheral nerve in a light microscope tissue section.

A

smooth muscle, dense regular connective tissue

23
Q

In some neurons, the cytoplasm may contain _____ _____. These are also
called ‘age pigment’ because they increase in number and prominence with age;

A

lipofuscin granules

24
Q

What are the three types of neurons and how do they differ?

A

Multipolar neurons are characterized by mutiple dendrites
emerging from the cell body and a single axon, bipolar neurons have two dendritic processes
(one serves as an input process, the other as an output process), and unipolar (also
known as pseudounipolar) neurons have one process.