Nervous System Drug Classes - Interactions

Question 1

What do most antidepressants interact with?

Answer 1

Interacts with Other Serotonergic: Causes “serotonin syndrome” - (can cause mental status changes, tremor, restlessness, fever, flushing, diarrhea, sweating, and blood pressure)

Question 2

What is the interaction of antidepressants and St. John Wort?

Answer 2

St. John Wort is a “natural antidepressant” causing “serotonin syndrome”.

Question 3

What does class SSRIs/Misc interact with?

Answer 3

Antidepressants

Interacts with Amiodarona: Should NOT be taken with QT meds (time interval within specific part of a heartbeat) as it can lead serious irregular heart rhythms or even sudden death

Question 4

What does class SSRIs/Misc interact with?

Answer 4

Antidepressants

Interacts with Aged Cheese & other tyramine-containing foods: Can cause hypertension (HBP)

Question 5

What class is Carbamazepine in and what does it interact with?

Answer 5

Brand Name: Tegretol
Mood Stabilizers and Antipsychotics
Drug Class: Mood Stabilizers
Interacts with Hormonal Contraceptives: Breaks down oral contraceptive levels quickly, reducing efficacy (could result in an unintended pregnancy)

Question 6

What class is Lithium in and what does it interact with?

Answer 6

Brand Name: Lithobid
Mood Stabilizers and Antipsychotics
Drug Class: Mood Stabilizers
Interacts with Amiodarone: interacts with QT meds (time interval within specific part of a heartbeat) as it can lead serious irregular heart rhythms or even sudden death

Question 7

What does class Atypical Antipsychotics interact with?

Answer 7

Mood Stabilizers and Antipsychotics

Interacts with Amiodarone: Interacts with QT meds (time interval within specific part of a heartbeat) as it can lead serious irregular heart rhythms or even sudden death

Question 8

What does class Benzodiazepines interact with?

Answer 8

Anxiolytics and Sedative Hypnotics

Interacts with Opioids: Increases risk of dizziness and drowsiness. Dangerously slowed breathing

Question 9

What does class Sedative-Hypnotics interact with?

Answer 9

Anxiolytics and Sedative Hypnotics

Interacts with Muscle-Relaxants: Increases risk of dizziness and drowsiness. Dangerously slowed breathing

Question 10

What interacts with both Anxiolytics/Sedative-hypnotic classes?

Answer 10

Anxiolytics and Sedative Hypnotics
Brand Name: Lithobid
Drug Class: Mood Stabilizers
Interacts with Alcohol: Increases risk of dizziness and drowsiness. Dangerously slowed breathing

Question 11

What class is Atomoxetine in and what does it interact with?

Answer 11

ADHD
Brand Name: Strattera
Drug Class: Non-Stimulants
Interacts with Other Serotonergic Meds: “Serotonin syndrome”

Question 12

What class is Clonidine in and what does it interact with?

Answer 12

ADHD
Brand Name: Kapvay
Drug Class: Non-Stimulants
Interacts with Other Blood Pressure Meds: “Serotonin syndrome”

Question 13

What does class Stimulants interact with?

Answer 13

ADHD

Interacts with Other stimulant meds: Can increase side effects (nervousness, irritability, nausea, insomnia, arrythmias, tremors)

Question 14

What class is Dilantin in and what does it interact with?

Answer 14

Anticonvulsants
Brand Name: Kapvay
Drug Class: Hydantoins
Interacts with Antifungals: Decreases effectiveness of antifungal

Question 15

What class is Carbamazepine in and what does it interact with?

Answer 15

Anticonvulsants
Brand Name: Tegretol
Drug Class: Misc Anticonvulsants
Interacts with Hormonal Contraceptives: Break down hormonal contraceptives (unintended pregnancy eminent)

Question 16

What class is Levodopa/Carbidopa in and what does it interact with?

Answer 16

Parkinson’s and Alzheimer’s Disease Meds
Brand Name: Tegretol
Drug Class: Dopamine Agents
Interacts with MAOIs: Can lead to a hypertensive crisis and can be fatal

Question 17

What does class MAOIs (Monoamine Oxidase Inhibitors) interact with?

Answer 17

Parkinson’s and Alzheimer’s Disease Meds

Interacts with Beer and other tyramine containing foods (like aged cheese): Can cause hypertension

Question 18

What class is Ropinirole in and what does it interact with?

Answer 18

Parkinson’s and Alzheimer’s Disease Meds
Brand Name: Requip
Drug Class: Dopamine Agents
Interacts with Benzodiazepines: Cause excessive sedation

Question 19

What does class Triptans interact with?

Answer 19

Migraine Medications

Interacts with SSRIs: “Serotonin Syndrome”

Question 20

What class is Ketamine in and what does it interact with?

Answer 20

Anesthetics
Brand Name: Ketalar
Drug Class: Anesthetics
Interacts with Other Sedating Meds: Increases risk of dizziness and drowsiness, dangerously slowed breathing