Nervous System Drug Classes - Interactions Flashcards
What do most antidepressants interact with?
Interacts with Other Serotonergic: Causes “serotonin syndrome” - (can cause mental status changes, tremor, restlessness, fever, flushing, diarrhea, sweating, and blood pressure)
What is the interaction of antidepressants and St. John Wort?
St. John Wort is a “natural antidepressant” causing “serotonin syndrome”.
What does class SSRIs/Misc interact with?
Antidepressants
Interacts with Amiodarona: Should NOT be taken with QT meds (time interval within specific part of a heartbeat) as it can lead serious irregular heart rhythms or even sudden death
What does class SSRIs/Misc interact with?
Antidepressants
Interacts with Aged Cheese & other tyramine-containing foods: Can cause hypertension (HBP)
What class is Carbamazepine in and what does it interact with?
Brand Name: Tegretol
Mood Stabilizers and Antipsychotics
Drug Class: Mood Stabilizers
Interacts with Hormonal Contraceptives: Breaks down oral contraceptive levels quickly, reducing efficacy (could result in an unintended pregnancy)
What class is Lithium in and what does it interact with?
Brand Name: Lithobid
Mood Stabilizers and Antipsychotics
Drug Class: Mood Stabilizers
Interacts with Amiodarone: interacts with QT meds (time interval within specific part of a heartbeat) as it can lead serious irregular heart rhythms or even sudden death
What does class Atypical Antipsychotics interact with?
Mood Stabilizers and Antipsychotics
Interacts with Amiodarone: Interacts with QT meds (time interval within specific part of a heartbeat) as it can lead serious irregular heart rhythms or even sudden death
What does class Benzodiazepines interact with?
Anxiolytics and Sedative Hypnotics
Interacts with Opioids: Increases risk of dizziness and drowsiness. Dangerously slowed breathing
What does class Sedative-Hypnotics interact with?
Anxiolytics and Sedative Hypnotics
Interacts with Muscle-Relaxants: Increases risk of dizziness and drowsiness. Dangerously slowed breathing
What interacts with both Anxiolytics/Sedative-hypnotic classes?
Anxiolytics and Sedative Hypnotics
Brand Name: Lithobid
Drug Class: Mood Stabilizers
Interacts with Alcohol: Increases risk of dizziness and drowsiness. Dangerously slowed breathing
What class is Atomoxetine in and what does it interact with?
ADHD
Brand Name: Strattera
Drug Class: Non-Stimulants
Interacts with Other Serotonergic Meds: “Serotonin syndrome”
What class is Clonidine in and what does it interact with?
ADHD
Brand Name: Kapvay
Drug Class: Non-Stimulants
Interacts with Other Blood Pressure Meds: “Serotonin syndrome”
What does class Stimulants interact with?
ADHD
Interacts with Other stimulant meds: Can increase side effects (nervousness, irritability, nausea, insomnia, arrythmias, tremors)
What class is Dilantin in and what does it interact with?
Anticonvulsants
Brand Name: Kapvay
Drug Class: Hydantoins
Interacts with Antifungals: Decreases effectiveness of antifungal
What class is Carbamazepine in and what does it interact with?
Anticonvulsants
Brand Name: Tegretol
Drug Class: Misc Anticonvulsants
Interacts with Hormonal Contraceptives: Break down hormonal contraceptives (unintended pregnancy eminent)
What class is Levodopa/Carbidopa in and what does it interact with?
Parkinson’s and Alzheimer’s Disease Meds
Brand Name: Tegretol
Drug Class: Dopamine Agents
Interacts with MAOIs: Can lead to a hypertensive crisis and can be fatal
What does class MAOIs (Monoamine Oxidase Inhibitors) interact with?
Parkinson’s and Alzheimer’s Disease Meds
Interacts with Beer and other tyramine containing foods (like aged cheese): Can cause hypertension
What class is Ropinirole in and what does it interact with?
Parkinson’s and Alzheimer’s Disease Meds
Brand Name: Requip
Drug Class: Dopamine Agents
Interacts with Benzodiazepines: Cause excessive sedation
What does class Triptans interact with?
Migraine Medications
Interacts with SSRIs: “Serotonin Syndrome”
What class is Ketamine in and what does it interact with?
Anesthetics
Brand Name: Ketalar
Drug Class: Anesthetics
Interacts with Other Sedating Meds: Increases risk of dizziness and drowsiness, dangerously slowed breathing
