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Bioscience II Brandon > Nervous system D/o-PPt -Josh > Flashcards

Nervous system D/o-PPt -Josh Flashcards

1
Q

Parkinson’s Disease:

PD is known as a neuro______ diseaae

A

NeuroDEGENERATIVE

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2
Q

Parkinson’s Disease:

what is the #1 risk factor?

A

Increasing Age

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3
Q

Parkinson’s Disease:

is a deficiency of dopaminergic innervation of the Basal Ganglia, from the _____ ______

A

Substantia Nigra

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4
Q

Parkinson’s Disease:

Degeneration of the ___________ pathway leads to depletion of the neurotransmitter dopamine

A

Nigrastriatal

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5
Q

Parkinson’s Disease:

S/S

A
  • Skeletal Muscle tremor
  • Rigidity
  • Akinesia
  • Bradykinesia
  • Postural Instability
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6
Q

Parkinson’s Disease:

what are the 2 types of regidity?

A
  1. Plastic rigidity- constant through ROM; lead pipe PROM
  2. Cogwheel rigidity- breif palpable jerks
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7
Q

Parkinson’s Disease:

what is Akinesia

A
  • An absence or lack of control of voluntary muscle groups
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8
Q

Parkinson’s Disease:

what is bradykinesia

A

Slowness of voluntary movement

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9
Q

Parkinson’s Disease: Anesthesia

do these pt’s continue Levodopa preop

A

yepper

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10
Q

Parkinson’s Disease: Anesthesia

what are 3 pharmacological treatment options

A
  • Levodopa
  • Synthetic Dopamine Agonist
  • Anticholinergic
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11
Q

Parkinson’s Disease: Anesthesia

what are 3 drugs to avoid giving to these pt’s?

A

Droperidol

Haloperidol

Alfentanil

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12
Q

what is a chronic and progressive autoimmune d/o involving the demyelination of axons?

A

MS

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13
Q

Multpile Sclerosis:

MS is specific to what part of the nervous system

A

CNS

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14
Q

Multpile Sclerosis:

the irreversible damage is called by what 5 thinks

A
  • Inflammation
  • Oligodendrocyte injury
  • Demyelination
  • Axonal Degeneration
  • Formation of Plaques
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15
Q

Multpile Sclerosis:

Symptoms/ how does it appear for example constant ot remissions

A
  • exacerbations
  • Relapses
  • Remissions
  • eventually Symptoms persist during remissions, leading to severe disability
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16
Q

Multpile Sclerosis:

whare does demylination occur (3), and what is the manifestation?

A
  • Optic Nerve- Visual failure
  • Cerebellum Involvement- Gait disturbances
  • Spinal Cord Lesions- Skeletal muscle weakness/ urinary incontinenc/ Ataxia
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17
Q

Multpile Sclerosis: Anesthesia

Surgical stress can exacerbate the symptoms- and a temp change of __C can exacerbate symptoms

A

1

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18
Q

Multpile Sclerosis: Anesthesia

what MR do you want to avoid? why?

A

DMB (SCh)- d/t hyperkalemia

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19
Q

Huntington’s Disease:

is a heredity degenerative d/o that is ________ dominant

A

Autosomal Dominant

20
Q

Huntington’s Disease:

effects what 2 parts of the brain?

A
  • basal Ganglia
  • Cerebral Cortex
21
Q

Huntington’s Disease:

it is also know as what name?

A

Chorea

22
Q

Huntington’s Disease:

the basal ganglia is depleted of what NT

A

GABA

23
Q

Huntington’s Disease:

S/S

A

Abnormal movement

Dementia

restlessness

irritabilty

24
Q

Huntington’s Disease: Anesthesia

the is an increased sensitivy to which MR ND or Dep?

A

Both

25
Q

Huntington’s Disease: Anesthesia

what 2 meds are great for pre-treatment

A
  • Droperidol
  • Halperidol
26
Q

What is the functional Abnormality associated w/ at least 1 never root?

A
  • radiculopathy
27
Q

Radiculopathy:

may be caused by what 3 things?

A
  1. compression
  2. Inflammation
  3. Acute trauma
28
Q

Huntington’s Disease: Anesthesia

Muscles innervated by involved nerve root may display what S/S

A
  • Atrophy
  • Weakness
  • decreased DTRs
  • sensry alterations
29
Q

what are the 3 types of neuropathies

A

Generalized

focal or multifocal

Generalized symmetric

30
Q

what type of Nueropathy affect the cell body of only ONE peripheral nerve?

A

Generalized

31
Q

Generalized Nueropathy:

what are the 2 types

A
  1. Motor
  2. Sensory
32
Q

Generalized Nueropathy:

ALS is an example of what type of Generalized Nueropathy:

A

Motor

33
Q

Generalized Nueropathy:

Leprosy and Industrial poisoning is an example of what type of Generalized Nueropathy:

A

Sensory

34
Q

What type of Neuropathy affect sensory or motor in one or more nerves?

A

Focal or Multifocal Neuropathies

35
Q

Focal or Multifocal Neuopathies:

what is an example of this?

A

Carpal tunnel syndrome

36
Q

what type of Neuropathy is SYMMETRIC involement of sensory, motor, or autonomic fibers?

A

Generalized Symmetric Polyneuopathies:

37
Q

Generalized Symmetric Polyneuopathies:

what are the 3 types

A
  1. Distal Axonal Polyneuopathies
  2. Demyelinated Polyneuopathies
  3. Axonal Degeneration
38
Q

Generalized Symmetric Polyneuopathies:

which one of the 3 is the most common?

A

Distal Axonal Polyneuopathies:

39
Q

Generalized Symmetric Polyneuopathies:

what is an example of Distal Axonal Polyneuopathies:

(hint think distal AKA legs)

A

DM

ETOH abuse

40
Q

Generalized Symmetric Polyneuopathies:

which one is the least common

A

Demylinating

41
Q

Generalized Symmetric Polyneuopathies:

what is an exaample of the demyelinating

A

Guillian- barre

42
Q

Generalized Symmetric Polyneuopathies:

how is axonal degeneration done

A

disatl dgeneration of axon fist followed by degeneration of myelin

43
Q

Myelopathy:

2 types

A
  1. HIV Myelopathy:
  2. Vascular Myelopathy:
44
Q

Myelopathy:

which one is DIFFUSE degeneration of the spinal cord

A

HIV Myelopathy:

45
Q

Myelopathy:

then I guess… which one is Lateral and posterior spinal colums of the lumbar spinal cord! And progressive spastic paraparesis w/ ataxia

A

vascular Myelopathy:

46
Q

Thats it

A

your done

Bioscience II Brandon (11 decks)

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